![]() | Edited by: Suzanne Kennedy and Nick Oswald Published: 2011 ISBN: 978-1-904455-72-1 Price: GB £159 or US $310 Strategies for preparing effective controls and standards for PCR, when they should be employed and how to interpret the information they provide. The significance of optimization for efficiency, precision and sensitivity of PCR methodology and essential guidance on how to troubleshoot inefficient reactions. Design and optimization techniques, the use of appropriate controls, the significance of standard curves and the principles and strategies required for effective troubleshooting. The importance of sample preparation and quality, primer design, controlling inhibitors, avoiding amplicon and environmental contamination, optimizing reagent quality and concentration, and modifying the thermal cycling protocol for optimal sensitivity and specificity. read more ... |
![]() | Edited by: Aharon Oren and R. Thane Papke Published: 2010 ISBN: 978-1-904455-67-7 Price: GB £159 or US $310 Current concepts in molecular phylogeny and their application with respect to microorganisms. The different approaches applied to elucidate the molecular phylogeny of prokaryotes; reviews of current phylogenetic methods, techniques and software tools. Topics include a historical overview, computational tools, multilocus sequence analysis, 16S rRNA phylogenetic trees, rooting of the universal tree of life, applications of conserved indels, lateral gene transfer, endosymbiosis and the evolution of plastids. read more ... |
![]() | Edited by: Jianping Xu Published: 2010 ISBN: 978-1-904455-59-2 Price: GB £159 or US $310 Major current advances in microbial population genetics and genomics. Fundamental concepts, genetic tools and comprehensive reviews of recent data from SNP surveys, whole-genome DNA sequences and microarray hybridizations. Covers broad groups of microorganisms including viruses, bacteria, archaea, fungi, protozoa and algae. A major focus is the application of molecular tools in the study of genetic variation. Topics include microbial systematics, comparative microbial genomics, horizontal gene transfer, pathogenic bacteria, nitrogen-fixing bacteria, cyanobacteria, microalgae, fungi, malaria parasites, viral pathogens and metagenomics. read more ... |
![]() | Edited by: Michael Y. Galperin and Eugene V. Koonin Published: 2003 ISBN: 978-0-9542464-4-0 Price: GB £90 or US $180 Computational biology and bioinformatics form a major, integral part of genomics. From sequence fragment assembly, to gene prediction, to prediction of protein functions and structure, to identification of regulatory signals in DNA, to building phylogenetic trees, it would not be an exaggeration to state that genomics is primarily computational. Major new programs, software and internet facilities have evolved recently that facilitate computational analysis and more novel technologies are currently being developed. Written by experts in the field, this volume highlights research on the emerging, perhaps somewhat controversial, topics in genomics and shows the feedback between the new developments and the established methods of computational biology. An essential book for anyone involved in genomic science or bioinformatics. read more ... |
![]() | Edited by: Antoine Danchin Published: 2002 ISBN: 978-0-9542464-3-3 Price: GB £75 or US $150 Eminent scientists have contributed comprehensive reviews on all aspects of the genomics of Rhodococcus, Mycobacteria, Streptomyces and other organisms. The authors provide an insight into the many facets of large-scale functional investigation in a variety of bacteria with the explicit goal to find common rules in the dynamic and structural organisation of these organisms. This volume is the definitive guide to current research in this increasingly important area. read more ... |
![]() | Edited by: David J. Galas Published: 2002 ISBN: 978-0-9542464-2-6 Price: GB £90 or US $180 The chapters in this book reflect the range of technical advances and their applications that are currently transforming biology. Topics covered include the application of computational methods, the robotics of modern automation methodologies, the new chemical and imaging methods that reveal chromosome structure and elucidate gene function, and the emergence of evolutionary and functional information by comparative genomics. Eminent international scientists describe in detail the new technology necessary to study the entire genome in a holistic manner and all the high throughput and large-scale experimental methodologies currently being used in genomic science. In addition the authors describe the progress of the newest technologies that are currently being developed. read more ... |