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Bioinformatics Books

Our high level bioinformatics books bring together expert international authors under the skilled editorship of leading scientists to produce state-of-the-art compendiums of current research. Aimed at the research scientist, graduate student, medical reseacher and other professionals, these books are highly recommended for all bioinformatics laboratories. Every bioinformatics, microbiology and bioscience library should have a copy of each of the following books.
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Proteomics: Targeted Technology, Innovations and Applications
Edited by: Manuel Fuentes and Joshua LaBaer
Published: 2014
Hardback: ISBN 978-1-908230-46-1 £159, $319. Ebook: ISBN 978-1-908230-62-1 £159, $319
In this book a panel of high-profile authors provides an overview of targeted proteomics in biomedical science. The book is focused on current, state-of-the-art technology and applications and is a valuable source of information for everyone working in this field. The first part of the book provides detailed examples of the application of targeted proteomics in biomarker discovery and pathogenesis. The second part is focused on the various tools used in targeted proteomics including bioinformatics approaches while the final section is dedicated to biobanks, a vital aspect of targeted proteomics. This volume is highly recommended for anyone interested in proteomics, disease pathogenesis, clinical protein science and biomarker discovery. read more ...
Bioinformatics and Data Analysis in Microbiology
Edited by: Özlem Taştan Bishop
Published: 2014
Hardback: ISBN 978-1-908230-39-3 £159, $319. Ebook: ISBN 978-1-908230-73-7 £159, $319
This book provides invaluable, up-to-date and detailed information on various aspects of bioinformatics data analysis with applications to microbiology. It describes a number of different useful bioinformatics tools, makes links to some wet-lab techniques, explains different approaches to tackle a problem, talks about current challenges and limitations, gives examples of applications of bioinformatics methods to microbiology, and discusses future trends. The chapters include topics such as genome sequencing techniques, assembly, SNP analysis, annotation, comparative genomics, microbial community profiling, metagenomics, phylogenetic microarrays, barcoding and more. Each chapter is written by scientists who are expert in the field, and is peer-reviewed. Bioinformatics and Data Analysis in Microbiology is an essential book for researchers, lecturers and students involved in microbiology, bioinformatics and genome analysis. read more ...
Next-generation Sequencing: Current Technologies and Applications
Edited by: Jianping Xu
Published: 2014
Hardback: ISBN 978-1-908230-33-1 £120, $240. Ebook: ISBN 978-1-908230-95-9 £120, $240
Written by experts from around the world, this book explores the most recent advances in NGS instrumentation and data analysis. The book begins with a comprehensive description of current NGS platforms, their sequencing chemistries, instrument specifications, and general workflows and procedures. A separate chapter is dedicated to low-quantity, single molecule sequencing technology. Further chapters explore the application of NGS technologies in various fields including polymorphism detection, sRNA research, rare variant detection, large variant detection, exome sequencing, plant development studies, microbial metagenomics, and studies on the human microbiome. Practical and cutting-edge, this volume represents an excellent collection of chapters to aid all scientists who wish to apply these innovative research tools. read more ...
Genome Analysis: Current Procedures and Applications
Edited by: Maria S. Poptsova
Published: 2014
Hardback: ISBN 978-1-908230-29-4 £159, $319. Ebook: ISBN 978-1-908230-68-3 £159, $319
In this book, an impressive array of expert authors highlight and review current advances in genome analysis. This volume provides an invaluable, up-to-date and comprehensive overview of the methods currently employed for next-generation sequencing (NGS) data analysis, highlights their problems and limitations, demonstrates the applications and indicates the developing trends in various fields of genome research. The first part of the book is devoted to the methods and applications that arose from, or were significantly advanced by, NGS technologies: the identification of structural variation from DNA-seq data; whole-transcriptome analysis and discovery of small interfering RNAs (siRNAs) from RNA-seq data; motif finding in promoter regions, enhancer prediction and nucleosome sequence code discovery from ChiP-Seq data; identification of methylation patterns in cancer from MeDIP-seq data; transposon identification in NGS data; metagenomics and metatranscriptomics; NGS of viral communities; and causes and consequences of genome instabilities. The second part is devoted to the field of RNA biology with the last three chapters devoted to computational methods of RNA structure prediction including context-free grammar applications. An essential book for everyone involved in sequence data analysis, next-generation sequencing, high-throughput sequencing, RNA structure prediction, bioinformatics and genome analysis. read more ...
Systems Microbiology: Current Topics and Applications
Edited by: Brian D. Robertson and Brendan W. Wren
Published: 2012
Hardback: ISBN 978-1-908230-02-7 £159, $319
This volume contains cutting-edge reviews by world-leading experts on the systems biology of microorganisms. As well as covering theoretical approaches and mathematical modelling this book includes case studies on single microbial species of bacteria and archaea, and explores the systems analysis of microbial phenomena such as chemotaxis and phagocytosis. Topics covered include mathematical models for systems biology, systems biology of Escherichia coli metabolism, bacterial chemotaxis, systems biology of infection, host-microbe interactions, phagocytosis, system-level study of metabolism in Mycobacterium tuberculosis, and the systems biology of Sulfolobus. This book is a major resource for anyone interested in systems biology and a recommended text for all microbiology laboratories. read more ...
Epigenetics: A Reference Manual
Edited by: Jeffrey M. Craig and Nicholas C. Wong
Published: 2011
Hardback: ISBN 978-1-904455-88-2 £180, $360
The editors of this book have assembled top-quality scientists from diverse fields of epigenetics to produce a major new volume. Comprehensive and cutting-edge, the 26 chapters in this book constitute a key reference manual for everyone involved in epigenetics, DNA methylation, cancer epigenetics and related fields. Topics include: early life environment, DNA methylation and behavior, histone acetyltransferase biology, transgenerational epigenetic inheritance, mammalian X inactivation, epigenetic memory in plants, polycomb-group regulation, centromeres and telomeres, DNA sequence contribution to nucleosome distribution, macrosatellite epigenetics, histones, cell-fate specification and reprogramming, DNA methylation in cancer, variant histone H2A and cancer development, RNA modification, paramutation in plants, DNMT3L dependent methylation during gametogenesis, non-coding RNA, bisulphite-enabled technologies, rapid analysis of DNA methylation, microarray mapping, DNA methylation profiling, ChIP-sequencing, genome-wide DNA methylation analysis, and epigenetics in maize. In addition there are useful chapters on bioinformatics in epigenomics, online resources and tools for epigeneticists, and educational resources for epigenetics. This up-to-date reference manual is an essential book for those working in the field and for scientists in other disciplines it represents a major information resource on the fascinating and fast-moving field of epigenetics. read more ...
PCR Troubleshooting and Optimization: The Essential Guide
Edited by: Suzanne Kennedy and Nick Oswald
Published: 2011
Hardback: ISBN 978-1-904455-72-1 £159, $319
This book discusses the strategies for preparing effective controls and standards for PCR, when they should be employed and how to interpret the information they provide. It highlights the significance of optimization for efficiency, precision and sensitivity of PCR methodology and provides essential guidance on how to troubleshoot inefficient reactions. Experts in PCR describe design and optimization techniques, discuss the use of appropriate controls, explain the significance of standard curves and explore the principles and strategies required for effective troubleshooting. Authors highlight the importance of sample preparation and quality, primer design, controlling inhibitors, avoiding amplicon and environmental contamination, optimizing reagent quality and concentration, and modifying the thermal cycling protocol for optimal sensitivity and specificity. In addition, specific chapters discuss the history of PCR, the choice of instrumentation, the applications of PCR in metagenomics, high resolution melting analysis, the MIQE guidelines, and PCR at the microliter scale. The strategies, tips and advice contained in this concise volume enable the scientist to optimize and effectively troubleshoot a wide range of techniques including PCR, reverse transcriptase PCR, real-time PCR and quantitative PCR. An essential book for anyone using PCR technology. read more ...
Molecular Phylogeny of Microorganisms
Edited by: Aharon Oren and R. Thane Papke
Published: 2010
Hardback: ISBN 978-1-904455-67-7 £159, $319
In this book, leading scientists from around the world explore current concepts in molecular phylogeny and their application with respect to microorganisms. The authors describe the different approaches applied today to elucidate the molecular phylogeny of prokaryotes (and eukaryotic protists) and review current phylogenetic methods, techniques and software tools. Topics covered include: a historical overview, computational tools, multilocus sequence analysis, 16S rRNA phylogenetic trees, rooting of the universal tree of life, applications of conserved indels, lateral gene transfer, endosymbiosis and the evolution of plastids. This book is an ideal introduction to molecular phylogeny for all microbiologists and is an essential review of current concepts for experts in the field. A recommended text for all microbiology laboratories. read more ...
Microbial Population Genetics
Edited by: Jianping Xu
Published: 2010
Hardback: ISBN 978-1-904455-59-2 £159, $319
Written by leading researchers in the field, this invaluable book details the major current advances in microbial population genetics and genomics. Distinguished international scientists introduce fundamental concepts, describe genetic tools and comprehensively review recent data from SNP surveys, whole-genome DNA sequences and microarray hybridizations. Chapters cover broad groups of microorganisms including viruses, bacteria, archaea, fungi, protozoa and algae. A major focus of the book is the application of molecular tools in the study of genetic variation. Topics covered include microbial systematics, comparative microbial genomics, horizontal gene transfer, pathogenic bacteria, nitrogen-fixing bacteria, cyanobacteria, microalgae, fungi, malaria parasites, viral pathogens and metagenomics. An essential volume for everyone interested in population genetics and highly recommended reading for all microbiologists. read more ...
Frontiers in Computational Genomics
Edited by: Michael Y. Galperin and Eugene V. Koonin
Published: 2003
Hardback: ISBN 978-0-9542464-4-0 £159, $319
Computational biology and bioinformatics form a major, integral part of genomics. From sequence fragment assembly, to gene prediction, to prediction of protein functions and structure, to identification of regulatory signals in DNA, to building phylogenetic trees, it would not be an exaggeration to state that genomics is primarily computational. Major new programs, software and internet facilities have evolved recently that facilitate computational analysis and more novel technologies are currently being developed. Written by experts in the field, this volume highlights research on the emerging, perhaps somewhat controversial, topics in genomics and shows the feedback between the new developments and the established methods of computational biology. An essential book for anyone involved in genomic science or bioinformatics. read more ...
Genomics of GC-Rich Gram-Positive Bacteria
Edited by: Antoine Danchin
Published: 2002
Hardback: ISBN 978-0-9542464-3-3 £159, $319
Eminent scientists have contributed comprehensive reviews on all aspects of the genomics of Rhodococcus, Mycobacteria, Streptomyces and other organisms. The authors provide an insight into the many facets of large-scale functional investigation in a variety of bacteria with the explicit goal to find common rules in the dynamic and structural organisation of these organisms. This volume is the definitive guide to current research in this increasingly important area. read more ...
Genomic Technologies: Present and Future
Edited by: David J. Galas and Stephen J. McCormack
Published: 2002
Hardback: ISBN 978-0-9542464-2-6 £159, $319
The chapters in this book reflect the range of technical advances and their applications that are currently transforming biology. Topics covered include the application of computational methods, the robotics of modern automation methodologies, the new chemical and imaging methods that reveal chromosome structure and elucidate gene function, and the emergence of evolutionary and functional information by comparative genomics. Eminent international scientists describe in detail the new technology necessary to study the entire genome in a holistic manner and all the high throughput and large-scale experimental methodologies currently being used in genomic science. In addition the authors describe the progress of the newest technologies that are currently being developed. Written by experts in the field, this concise yet informative volume covers all aspects of technology pertaining to genomic studies. An essential book for anyone involved in genomic science. Readership: bioscientists, molecular biologists, biotechnologists, geneticists, human, animal and plant geneticists, microbiologists, genome scientists. An essential book for anyone involved in genomic science. read more ...