In recent years the development of new molecular biology tools and the elucidation of whole genome sequences have revolutionized research in medical mycology. Such advances have led to the development of faster, more reliable diagnostic techniques for medically important pathogens such as
Candida albicans,
Aspergillus fumigatus and
Cryptococcus neoformans. In addition they have led to a major breakthrough in the approach for the generation of novel anti-fungal agents.
In a recent book on
Medical Mycology a panel of expert international mycologists critically review the most important areas. Topics include: gene expression and regulation, heterozygosity in
Candida, molecular diagnosis, regulation of the host-fungal interaction, the development of anti-fungals, signal transduction, and mechanisms of multi-drug resistance.
Further reading:
Pathogenic Fungi: Insights in Molecular Biology