Actin Cytoskeleton of Entamoeba histolytica

Host tissue invasion by E. histolytica is driven by motility and phagocytosis, which are both regulated primarily by reorganization of the actin cytoskeleton. The structural and signaling components of the actin cytoskeleton from available genomes of three Entamoeba species, E. histolytica, E.dispar and E. invadens, have been annotated manually and compared systematically. These protein families include the actin superfamily, actin nucleators, calponin-related actin-binding proteins (ABPs), gelsolin-related ABPs, myosins, small GTPases and their regulators, as well as phospholipid signaling regulators.

from Anaerobic Parasitic Protozoa: Genomics and Molecular Biology

Further reading:

• Anaerobic Parasitic Protozoa
• Acanthamoeba: Biology and Pathogenesis
• Leishmania: After The Genome

Labels: Actin, Actin nucleators, Actin superfamily, E dispar, E histolytica, E invadens, Entamoeba histolytica, motility, Phagocytosis, Small GTPases