Feline calicivirus (FCV) represents an important pathogen of cats that has been studied extensively on the molecular level. FCV was the first calicivirus for which milestones like a reverse genetics system or the identification of a verified virus receptor were reached. Recently, great efforts were made to investigate unusual mechanisms of translation initiation driven by the RNA bound protein VPg or an RNA structure named TURBS.

Further reading: Caliciviruses: Molecular and Cellular Virology

Labels: Calicivirus, FCV