from Paola Mastrantonio (Istituto Superiore di Sanita, Rome, Italy)
writing in Society for Microbial Ecology and Disease read more ..."This book represents a comprehensive update on the current understanding of the molecular mechanisms of pathogenesis both in
Neisseria meningitidis and
Neisseria gonorrhoeae. The understanding of the gene expression strategies of pathogenic
Neisseria is still limited but the recently published genome sequences of both the above mentioned species will provide invaluable insights into the basis of pathogenesis as well as on the study of new therapeutic interventions and preventive tools. Mechanisms of adhesion, cellular invasion, interference with the apoptotic cellular machinery and of antibiotic resistance are illustrated such as the role of the innate and acquired immunity in
Neisseria infections. A comprehensive chapter is dedicated to the epidemiology of the diseases caused by the two species. Further, the most recent approaches for a future prevention these diseases by a universal neisserial vaccine are commented."
Further reading:Labels: book review, Book Reviews, Neisseria, Neisseria gonorrhoeae, Neisseria meningitidis