Alita A. Miller and Paul F. Miller (Antibacterials Research Unit, Pfizer Worldwide, Groton, USA) present a new book on
Emerging Trends in Antibacterial Discovery: Answering the Call to Arms In this book, respected international experts summarize the most important concepts and pioneering strategies currently being used to develop novel antibacterials. The book opens with chapters on cellular processes that could be used as novel antibacterial targets. Examples include cell division, efflux pumps, metabolite-sensing riboswitches and bacterial secretion systems. These are followed by excellent chapters on the identification of new, naturally occurring antibacterial agents, including phage and biosynthetically engineered compounds. Understanding the host-microbe interaction and microbial communities and how they can be exploited to develop new antibacterial strategies is discussed in subsequent chapters. Other topics included are: antibacterial vaccines adjuvants, host defence peptides, antibodies, within-host models, and diagnostics. A major reference volume on antibacterial research and how it impacts on public health worldwide, the book is essential reading for everyone working in antibacterial research and is a recommended volume for all microbiology libraries
read more ...  | Edited by: Alita A. Miller and Paul F. Miller ISBN: 978-1-904455-89-9 Publisher: Caister Academic Press Publication Date: August 2011 Cover: hardback
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Tags: antibiotic | antibacterial drugs | antibacterial vaccines | vaccine adjuvants | host defence peptides | antibacterial antibodies | within-host models | human microbiota | antimicrobial agent | antibiotic resistant bacteria | multidrug resistant | multidrug efflux pumps | broad-spectrum antibiotic | biofilm | quorum-sensing | Anti-TB drug | Mycobacterium tuberculosis | host-defense-peptide | phage therapy