Brucella

IIgnacio López-Goñi and David O'Callaghan (Universidad de Navarra, Pamplona (Navarra), Spain; Université de Montpellier, Nimes, France, respectively) present a new book on Brucella: Molecular Microbiology and Genomics
Written by highly acclaimed Brucella scientists, this book comprehensively reviews the most important advances in the field. Opening chapters focus on genetic diversity within Brucella, covering both classical and new species. Particular emphasis is given to how comparative genomics has led to advances in molecular diagnostics, taxonomy and phylogeny. Following chapters cover proteomic analysis, transcriptomic analysis, the VirB type IV secretion system, signalling complexes, e.g. the BvrR/BvrS two-component regulatory system and quorum sensing. These chapters highlight the intricate interplay between factors involved in virulence. Another chapter discusses the role of the Brucella cell envelope in bacterial virulence and evasion of host defences. The final two chapters review the current strategies for the development of novel antibacterial agents and improved vaccines. This volume is essential reading for everyone with an interest in Brucella and brucellosis. It is also recommended reading for the wider body of scientists, veterinarians and MDs with an interest in microbial diagnostics, microbial pathogenesis, host-parasite interactions, cellular microbiologists and immunologists and vaccine development scientists read more ...
Brucella
Edited by: IIgnacio López-Goñi and David O'Callaghan
ISBN: 978-1-904455-93-6
Publisher: Caister Academic Press
Publication Date: February 2012
Cover: hardback
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