The Bacterial Life in the Cytosol

The Bacterial Life in the Cytosol

from Serge Mostowy and Pascale Cossart writing in Bacterial Pathogenesis: Molecular and Cellular Mechanisms:

To live inside host cells and replicate, pathogenic bacteria can either establish a niche in a vacuolar compartment or escape to the cytosol. In this chapter, we review our understanding of pathogenic mechanisms to escape and live in the cytosol, and highlight recent studies of bacterial survival strategies to counteract intracytosolic host defences.

Further reading: Bacterial Pathogenesis: Molecular and Cellular Mechanisms