Jane M. Carlton, Susan L. Perkins and Kirk W. Deitsch present a new book on
Malaria Parasites: Comparative Genomics, Evolution and Molecular Biology Since the publication of the first two
Plasmodium genome sequences in 2002, numerous other parasite genomes have been sequenced. These include the genomes of several more Plasmodium species as well as those of other apicomplexans, including species of
Toxoplasma, Cryptosporidium, Babesia, and
Eimeria. This wealth of genome sequence data has provided researchers with a powerful new tool, comparative genomics, which has revolutionised research in this area. In this book, expert authors from around the world comprehensively review the current advances in
Plasmodium comparative genomics, highlighting the fascinating new insights into parasite evolution and molecular biology that have ensued. Topics include:
Plasmodium taxonomy and phylogeny; the apicomplexan genomic landscape; the "art" of sequencing
Plasmodium genomes; diversity of
Plasmodium falciparum and
Plasmodium vivax genomes;
Plasmodium functional genomics;
Plasmodium experimental genetic crosses;
P. falciparum epigenetic modification and transcriptional regulation;
Plasmodium invasion of host red blood cells; protein export and trafficking by malaria parasites;
Plasmodium-mosquito vector interactions; and a practical guide to many of the revolutionary new techniques and molecular tools for
Plasmodium research. The book is essential reading for every researcher working with malaria parasites and related organisms, from the PhD student to the experienced scientist, and is a recommended text for all parasitologists
read more ... | Edited by: Jane M. Carlton, Susan L. Perkins and Kirk W. Deitsch ISBN: 978-1-908230-07-2 Publisher: Caister Academic Press Publication Date: February 2013 Cover: hardback
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