DNA Vaccines
Vaccine Strategies
Category: Immunology | Vaccines
Overview of Vaccine Strategies
from Ruth Arnon writing in Vaccine Design: Innovative Approaches and Novel Strategies
There are different strategies applied for vaccination against microbial diseases. These include vaccines against bacterial, viral and parasitic infections which led to tremendous improvement in public health. Both live attenuated or killed whole organisms and their sub-units can be used, as well as more novel approaches, such as DNA vaccines, recombinant vaccines and epitope-based, or peptide vaccines. There are advantages and disadvantages of each approach, eluding to various considerations, such as efficacy, safety and cost of production. The application of passive vaccination, including the use of pooled IgG (IVIG) is also possible. As indicated, these combined strategies led to a long list of vaccines that are presently approved and licensed in the USA, Europe and many other countries. Also important are the pediatric combination vaccines DPT and MMR that are used worldwide, and led to drastic reduction of the incidence of infectious diseases.
Further reading: Vaccine Design: Innovative Approaches and Novel Strategies
from Ruth Arnon writing in Vaccine Design: Innovative Approaches and Novel Strategies
There are different strategies applied for vaccination against microbial diseases. These include vaccines against bacterial, viral and parasitic infections which led to tremendous improvement in public health. Both live attenuated or killed whole organisms and their sub-units can be used, as well as more novel approaches, such as DNA vaccines, recombinant vaccines and epitope-based, or peptide vaccines. There are advantages and disadvantages of each approach, eluding to various considerations, such as efficacy, safety and cost of production. The application of passive vaccination, including the use of pooled IgG (IVIG) is also possible. As indicated, these combined strategies led to a long list of vaccines that are presently approved and licensed in the USA, Europe and many other countries. Also important are the pediatric combination vaccines DPT and MMR that are used worldwide, and led to drastic reduction of the incidence of infectious diseases.
Further reading: Vaccine Design: Innovative Approaches and Novel Strategies