NB-LRR Immune Receptors
NB-LRR Immune Receptors in Plant Virus Defense
NB-LRR Immune Receptors in Plant Virus Defense
from Patrick Cournoyer and Savithramma P. Dinesh-Kumar writing in Recent Advances in Plant Virology
Resistance genes protect plants from infection by viruses and many other classes of pathogens. The dominant, anti-viral R genes that have been cloned thus far encode NB-LRR immune receptors that detect a single viral protein and trigger defense. Many different types of viral proteins are known to elicit defense by corresponding NB-LRRs. Defense often results in a type of localized programmed cell death at the site of attempted pathogen infection known as the hypersensitive response (HR-PCD), but some NB-LRRs confer resistance to viruses without HR-PCD. The activation of NB-LRRs triggers manifold signaling events including reactive oxygen species (ROS) production, nitric oxide (NO) production, calcium (Ca2+) influx, activation of mitogen activated protein kinases (MAPKs), and production of the plant hormones salicylic acid (SA), jasmonic acid (JA), and ethylene. After a successful NB-LRR-mediated defense event, the plant exhibits heightened resistance to future pathogen challenge in a state called systemic acquired resistance.
Further reading: Recent Advances in Plant Virology | Virology Publications
from Patrick Cournoyer and Savithramma P. Dinesh-Kumar writing in Recent Advances in Plant Virology
Resistance genes protect plants from infection by viruses and many other classes of pathogens. The dominant, anti-viral R genes that have been cloned thus far encode NB-LRR immune receptors that detect a single viral protein and trigger defense. Many different types of viral proteins are known to elicit defense by corresponding NB-LRRs. Defense often results in a type of localized programmed cell death at the site of attempted pathogen infection known as the hypersensitive response (HR-PCD), but some NB-LRRs confer resistance to viruses without HR-PCD. The activation of NB-LRRs triggers manifold signaling events including reactive oxygen species (ROS) production, nitric oxide (NO) production, calcium (Ca2+) influx, activation of mitogen activated protein kinases (MAPKs), and production of the plant hormones salicylic acid (SA), jasmonic acid (JA), and ethylene. After a successful NB-LRR-mediated defense event, the plant exhibits heightened resistance to future pathogen challenge in a state called systemic acquired resistance.
Further reading: Recent Advances in Plant Virology | Virology Publications