Spore-forming bacteria
Streptomyces book
Paul Dyson (Institute of Life Sciences, School of Medicine, Swansea, UK) presents a new book on Streptomyces: Molecular Biology and Biotechnology
Streptomycetes are Gram-positive, high GC-content, sporulating bacteria found predominantly in soil. Streptomycetes are characterised by a complex secondary metabolism producing antibiotic compounds and other metabolites with medicinal properties. In recent years genomic studies, genomic mining and biotechnological approaches have been employed in the search for new antibiotics and other drugs.
With contributions from some of the leading scientists in the field, this volume documents recent research and development in streptomycetes genomics, physiology and metabolism. With a focus on biotechnology and genomics, the book provides an excellent source of up-to-date information. Topics include: genome architecture, conjugative genetic elements, differentiation, protein secretion, central carbon metabolic pathways, regulation of nitrogen assimilation, phosphate control of metabolism, gamma-butyrolactones and their role in antibiotic regulation, clavulanic acid and clavams, genome-guided exploration, gene clusters for bioactive natural products, genomics of cytochromes p450.
Streptomycetes are Gram-positive, high GC-content, sporulating bacteria found predominantly in soil. Streptomycetes are characterised by a complex secondary metabolism producing antibiotic compounds and other metabolites with medicinal properties. In recent years genomic studies, genomic mining and biotechnological approaches have been employed in the search for new antibiotics and other drugs.
With contributions from some of the leading scientists in the field, this volume documents recent research and development in streptomycetes genomics, physiology and metabolism. With a focus on biotechnology and genomics, the book provides an excellent source of up-to-date information. Topics include: genome architecture, conjugative genetic elements, differentiation, protein secretion, central carbon metabolic pathways, regulation of nitrogen assimilation, phosphate control of metabolism, gamma-butyrolactones and their role in antibiotic regulation, clavulanic acid and clavams, genome-guided exploration, gene clusters for bioactive natural products, genomics of cytochromes p450.
 | Edited by: Paul Dyson ISBN: 978-1-904455-77-6 Publisher: Caister Academic Press Publication Date: January 2011 Cover: hardback |
Essential reading for research scientists, biotechnologists, graduate students and other professionals involved in streptomycetes research, antibiotic and antimicrobial development, drug discovery, soil microbiology and related fields. A recommended text for all microbiology laboratories.
Bacterial Spores
Category: Bacteria
Endospore-forming bacteria produce some of the most potent toxins known and are important pathogens in hospital-borne infections (Clostridium difficile) food contamination (Bacillus cereus, Clostridium botulinum), wound infestation (Clostridium perfringens, Clostridium tetani) and bioterrorism (Bacillus anthracis).
Bacilli and Clostridia spores form in response to unfavorable environmental conditions and can withstand extremes of heat, radiation, and chemical agents. The spore's durability is even more remarkable considering that dormant spores revert back to actively growing cells almost immediately after nutrients return to the environment. The intrinsic resistance and the ability to remain dormant for long periods make spores the perfect delivery vehicle for infectious diseases.
Further reading: The Ger Receptor Family from Sporulating Bacteria
Bacilli and Clostridia spores form in response to unfavorable environmental conditions and can withstand extremes of heat, radiation, and chemical agents. The spore's durability is even more remarkable considering that dormant spores revert back to actively growing cells almost immediately after nutrients return to the environment. The intrinsic resistance and the ability to remain dormant for long periods make spores the perfect delivery vehicle for infectious diseases.
Further reading: The Ger Receptor Family from Sporulating Bacteria