The sequencing of the Entamoeba histolytica genome, as well as the development of genome-wide techniques to allow study of gene expression, has led to many advances in our understanding of the biology of this parasite. Recent work used genomic technologies (DNA microarrays and proteomics) to study important aspects of amebic biology, including pathogenesis, host interaction, phagocytosis, stage conversion, responses to stressful stimuli, and mechanisms of gene regulation. These studies identify pathways involved in regulating major functions in this important human pathogen.

from Anaerobic Parasitic Protozoa: Genomics and Molecular Biology

Further reading:

• Anaerobic Parasitic Protozoa
• Acanthamoeba: Biology and Pathogenesis
• Leishmania: After The Genome

Labels: Amebic biology, DNA microarrays, Proteomics