The genome of
Trichomonas vaginalis, the first from a parabasalid to be sequenced, was published in 2007, the culmination of a project marked by several surprises and not a little distress. The ~160 Mb genome was found to be significantly larger than first described, presenting new challenges to the standard genome sequencing pipeline.
from Anaerobic Parasitic Protozoa: Genomics and Molecular BiologyFurther reading:Labels: Parabasalid, Parabasalid genome, Trichomonas vaginalis
In a forthcoming book on
anaerobic protozoa, internationally acclaimed researchers critically review the most important aspects of research on anaerobic parasitic protozoa, providing the first coherent picture of their genomics and molecular biology since the publication of the genomes.
Chapters are written from a molecular and genomic perspective and contain speculative models upon which future research efforts can be based. Topics include: the genomes of
Entamoeba histolytica,
Trichomonas vaginalis,
Giardia and other diplomonads; the cytoskeletons of
Entamoeba histolytica,
Giardia lamblia and
Trichomonas vaginalis; genomic analyses and manipulation of gene expression in
Entamoeba histolytica; nuclear and chromosomal structure and replication in
Giardia; and the mitochondrion-like organelles of a fourth anaerobe,
Blastocystis.
from Anaerobic Parasitic Protozoa: Genomics and Molecular BiologyFurther reading:Labels: Blastocystis, Diplomonads, Entamoeba histolytica, Giardia, Giardia lamblia, Mitochondrion-like organelles, Trichomonas vaginalis