Anaerobic parasitic protozoa cause medically and economically important diseases such as dysentery, sexually transmitted infections, and gastroenteritis that affect millions of people worldwide annually. Recently the genomes of the three key anaerobic protozoa, Trichomonas, Giardia and Entamoeba, have been determined. The availability of these genomic data and the use of post-genomic analyses have provided fascinating new insights into the biology of these important parasites. They will be important for the design of novel anti-protozoan drugs and the development of effective vaccines.

A new book on Anaerobic Parasitic Protozoa critically reviews the most important aspects of research on anaerobic parasitic protozoa, providing the first coherent picture of their genomics and molecular biology since the publication of the genomes. Chapters are written from a molecular and genomic perspective and contain speculative models upon which future research efforts can be based. Topics include: the genomes of Entamoeba histolytica, Trichomonas vaginalis, Giardia and other diplomonads; the cytoskeletons of Entamoeba histolytica, Giardia lamblia and Trichomonas vaginalis; genomic analyses and manipulation of gene expression in Entamoeba histolytica; nuclear and chromosomal structure and replication in Giardia; and the mitochondrion-like organelles of a fourth anaerobe, Blastocystis. Recommended text for all parasitology laboratories.

Further reading: Anaerobic Parasitic Protozoa

Labels: Blastocystis, Entamoeba, Giardia, new book, parasites, parasitic infections, parasitology, parasitology books, Trichomonas

Lentiviruses and Macrophages: Molecular and Cellular Interactions
Edited by: Moira Desport
Published: 2010 ISBN: 978-1-904455-60-8
In this timely book, top lentivirus and macrophage specialists comprehensively review cutting-edge topics in the molecular and cellular biology of the lentivirus-macrophage interaction. Topics include lentivirus tropism and disease, macrophage biology, macrophage in HIV-1 infection and disease progression, post-entry restrictions to lentiviral replication, HIV-2 tropism and disease, SHIV model of disease, the felid immunodeficiency viruses, EIAV, small ruminant lentiviruses, bovine lentiviruses, coinfections and superinfections.

Further reading: Lentiviruses and Macrophages: Molecular and Cellular Interactions

Labels: aids, books, dengue virus, hiv, lentivirus, lentiviruses, new book, virology books, virus books

Borrelia: Molecular Biology, Host Interaction and Pathogenesis
Edited by: D. Scott Samuels and Justin D. Radolf
Published: 2010 ISBN: 978-1-904455-58-5

A comprehensive guide to Borrelia providing an encyclopedic overview of the molecular biology of this important genus and the pathogenesis of diseases Borellia causes. Leading authorities have contributed chapters on topics such as Borrelia genomics, DNA replication, gene regulation, transcriptomics, proteomics, metabolism and physiology, cellular structure, motility and chemotaxis, genetic manipulation, evolutionary genetics, ecology, tick interactions, Lyme disease and relapsing fever pathogenesis, animal models, host response, detection, and vaccines

Further reading: Borrelia: Molecular Biology, Host Interaction and Pathogenesis

Labels: books, borrelia, new book

Microbial Population Genetics
Edited by: Jianping Xu
Published: 2010 ISBN: 978-1-904455-59-2
Major current advances in microbial population genetics and genomics. Fundamental concepts, genetic tools and comprehensive reviews of recent data from SNP surveys, whole-genome DNA sequences and microarray hybridizations. Covers broad groups of microorganisms including viruses, bacteria, archaea, fungi, protozoa and algae. A major focus is the application of molecular tools in the study of genetic variation. Topics include microbial systematics, comparative microbial genomics, horizontal gene transfer, pathogenic bacteria, nitrogen-fixing bacteria, cyanobacteria, microalgae, fungi, malaria parasites, viral pathogens and metagenomics.

Further reading: Microbial Population Genetics

Labels: books, new book, population genetics

Caister Academic Press today announced the forthcoming publication of a new book Influenza: Molecular Virology.

In this timely book, internationally renowned scientists critically review the current research and the most important discoveries in this highly topical field. Subjects covered include the NS1 protein of influenza A virus, the structure of influenza NS1, influenza B hemagglutinin, influenza A nucleoprotein, influenza A hemagglutinin glycoproteins, the M2 channel, virulence genes of the 1918 H1N1 influenza, influenza virus polymerase, gene diagnostic microarrays, and computer-assisted vaccine design.

Further reading: Influenza: Molecular Virology

Labels: American Society for Virology, avian flu, books, flu, flu virus, new book