polysaccharides

polysaccharides

 

Polysaccharide book review

Chang-Chun Ling of University of Calgary, Canada writes in ChemBioChem (2009) 10: 2539-2540:

"a collection of reviews written by experts ... one of the most up-to-date and authoritative books available on topics about bacterial polysaccharides ... overall the book provides a substantial wealth of coverage ... with extensive references provided at the end of each chapter and the use of many experimental data to support scientific conclusions, I think that this book will prove to be a highly valuable resource for researchers and advanced students"

Bacterial Polysaccharides: Current Innovations and Future Trends
Publisher: Caister Academic Press
Editor: Matthias Ullrich
Publication date: 2009
ISBN: 978-1-904455-45-5

Further reading: Bacterial Polysaccharides: Current Innovations and Future Trends

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Just published: Bacterial Polysaccharides

A new book on Bacterial Polysaccharides has been published by Caister Academic Press. The book covers current research and biotechnological applications. Taking an interdisciplinary view the authors examine bacterial polysaccharides from molecular biology, genome-, transcriptome- and proteome-wide perspectives, and include ecological aspects and systems biology approaches.

Bacterial Polysaccharides: Current Innovations and Future Trends
Publisher: Caister Academic Press
Editor: Matthias Ullrich
Publication date: June 2009 (available now)
ISBN: 978-1-904455-45-5

Topics include:
* The Polysaccharide Peptidoglycan and How it is Influenced by (Antibiotic) Stress
* Genetics and Regulation of Bacterial Lipopolysaccharide Synthesis
* Mycobacterial Cell Wall Arabinogalactang
* Genetics and Regulation of Bacterial Polysaccharide Expression in Human Pathogenic Bacteria
* Therapies Directed at Pseudomonas aeruginosa Polysaccharides
* Immune Responses to Microbial Polysaccharides
* Polysaccharides of Gram-negative Periodontopathic Bacteria
* Bacterial Polysaccharides in Dental Plaque
* Composition and Functional Role of Polysaccharides in Biofilm Infections
* Poly-N-acetyl-glucosamine as a Mediator of Bacterial Biofilm Formation
* Surface Polysaccharides as Fitness factors of Rhizospheric Nitrogen-fixing Bacteria
* Levansucrase and Levan Formation in Pseudomonas syringae and Related Organisms
* Structure, Biosynthesis, and Regulation of Capsular Exopolysaccharide of Erwinia
* Osmoregulated Periplasmic Glucans (OPGs), Alginate, and Biofilm Formation in Pseudomonas syringae
* Ecology of Exopolysaccharide Formation by Lactic Acid Bacteria
* Biosynthesis and Chemical Composition of Exopolysaccharides Produced by Lactic Acid Bacteria
* Commercial Exploitation of Homo-exopolysaccharides in Non-dairy Food Systems
* Exploitation of Exopolysaccharides from Lactic Acid Bacteria
* Synthesis of Bacterial Polysaccharides as a Limiting Factor for Biofuel Production

Bacterial Polysaccharides: Current Innovations and Future Trends

CURRENT BOOKS OF INTEREST
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Lab-on-a-Chip Technology: Biomolecular Separation and Analysis
Lab-on-a-Chip Technology: Fabrication and Microfluidics
Bacterial Polysaccharides
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Bacterial Secreted Proteins
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Lipopolysaccharide

Lipopolysaccharide (LPS) is the major component of the outer leaflet of the outer membrane of Gram-negative bacteria. The LPS molecule is composed of two biosynthetic entities: the lipid A - core and the O-polysaccharide (O-antigen). Most biological effects of LPS are due to the lipid A part, however, there is an increasing body of evidence indicating that O-antigen (O-ag) plays an important role in effective colonization of host tissues, resistance to complement-mediated killing and in the resistance to cationic antimicrobial peptides that are key elements of the innate immune system.

Recently, data has started to accumulate on the intricacies in the genetic regulation of the structural components of this molecule and this is highly relevant to the biological function of the molecule.

from Skurnik M and Bengoechea JA in Bacterial Polysaccharides: Current Innovations and Future Trends (2009) Ullrich M (Ed) Published by Caister Academic Press

Further reading: Bacterial Polysaccharides

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Peptidoglycan

The peptidoglycan or murein sacculus is the stress-bearing structure of bacterial cells. It consists of glycan strands cross-linked by peptide bridges. Even though studies on murein have a very long tradition, it is not known how the glycan strands are actually arranged.

The chemical fine structure and the muropeptide composition of different Gram-negative and Gram-positive bacteria have been investigated in detail. Escherichia coli and Staphylococcus aureus are generally considered representatives for both Gram forms. During cell growth the stress-bearing structure has to be elongated and/or divided by the insertion of new and elimination of old material without losing its strength. Therefore multienzyme complexes containing both murein synthases and murein hydrolases have been postulated.

Peptidoglycan biosynthesis is the target for many antibiotics such as β-lactams, D-cycloserine and glycopeptide-antibiotics such as vancomycin. Bacteria have developed a number of different strategies for coping with antibiotic and osmotic stress.

from Ute Bertsche in Bacterial Polysaccharides: Current Innovations and Future Trends

Further reading:
  1. Bacterial Polysaccharides
  2. Microbial Production of Biopolymers and Polymer Precursors
  3. Microbiology Books

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