Molecular Biology: From Genomics to Probiotics
"the chapters are edited competently and constitute outstanding independent reviews ... very informative and provides a comprehensive overview of the genus Lactobacillus
Biospektrum (2009) 15: 348.
Further reading: LactobacillusMetagenomics: Theory, Methods and ApplicationsEnvironmental Molecular MicrobiologyBacterial PolysaccharidesBacterial Secreted ProteinsBiopolymers
Labels: lactic acid bacteria, lactobacilli, lactobacillus, probiotics
The Role of Fermented Food in the Maintenance of Health
June 8, 2009. The Role of Fermented Food in the Maintenance of Health
Zilina, Slovakia Further information
Fermented foods are not only important sources of preserved nutrients but have also great potential in maintaining health and preventing diseases. Traditional fermented foods can serve as functional foods when eaten for specified health purposes, because of their content of one or more nutrients or non-nutrient substances which can confer health benefits.
Although already used for thousands of years in human nutrition it is today that the health promoting functionality of fermented foods becomes more and more in the focus of scientific and public interest. It is the purpose of the symposium to highlight the role and functionality of dali, kefir, yoghurt, cheese, miso, natto, tempeh, kimchi, sauerkraut, sourdough, bread drink, shubat, doenjang, gundruk, kombucha, ogi and other indigenous fermented foods and non-alcoholic fermented beverages.
Expert scientists and researchers will present there findings and visions about fermented foods as functional foods of the past, presence and future within the following areas: Lactic fermentation and health; Lactobacillus plantarum and human health; Kefir and yoghurt in health promotion; Bacillus-based fermented food and health; Non-dairy fermented foods and health; Vegetable-based fermented food as health influencer; Fermented non-alcoholic beverages; Novel fermented foods with health effect; Mechanisms of action; The future of fermented foods as functional foods.Suggested reading: Lactobacillus Molecular Biology: From Genomics to Probiotics
Labels: fermented food, probiotics
Jens Walter (University of Nebraska) in
"... an interesting blend of fundamental and applied topics relevant to the use of these important organisms in research and industry. Fundamental aspects covered in the book are taxonomy, metabolism, stress response, genomics, and surface proteins of lactobacilli. Also included are chapters on applications of Lactobacillus
strains and their potential as probiotics in the treatment of diseases such as cancer or urinary tract infections.
... contributions from respected international scientists, many of which are leaders in their respective fields, this book constitutes an authoritative resource about both fundamental research and applications of lactobacilli. ... essential and up to date information for anyone interested in the biology of lactobacilli. The book will clearly be of interest to microbiologists, nutritionists, food scientists, and medical practitioners alike, and it is a valuable contribution to the probiotic
Further reading: Lactobacillus
Labels: book review, lactic acid bacteria, lactobacilli, lactobacillus, probiotics
From Probiotics to Therapeutic Drugs
The human intestine harbours an immense collection of microbes which have co-evolved with us. Recent studies indicate that the gut microbes regulate energy harvest from the diet and participate in the peripheral body metabolism. Gut microbial dysbiosis severely affects many body functions, including a complex interplay of gut-brain interactions, now under intense study. Most probiotic strains belong to the genus Lactobacillus
. The promising results of a first generation of probiotic microbes indicate a promising future for coming generations of probiotics. Antibiotic-associated, travellers' and pediatric diarrhea have been most studied, and more recently, inflammatory bowel disease and irritable bowel syndrome. Future probiotics may contain mixes of strains with complementary characteristics, tailormade for different gastrointestinal diseases, vaginosis or as delivery systems for vaccines, immunoglobulins and other protein based therapies.from
Ljungh and Wadstrom in Lactobacillus Molecular Biology: From Genomics to Probiotics
Labels: biotherapeutics, lactic acid bacteria, lactobacillus, probiotics
Probiotic Yeast - Saccharomyces boulardii as a biotherapeutic agent
Several pharmaceutical preparations containing probiotic yeast cells are commercially available and the beneficial properties of strains of some Saccharomyces
spp are well documented. As well as providing nutritive value probiotic yeasts are generally resistant to gastrointestinal passage and are resistant to most antibiotics. A recent review by Zanello et al. entitled Saccharomyces boulardii effects on gastrointestinal diseases
was recently published in the journal Current Issues in Molecular Biology
, a species of yeast, has been described as a biotherapeutic agent since several clinical trials displayed its beneficial effects in the prevention and the treatment of intestinal infections and in the maintenance of inflammatory bowel disease. All these diseases are characterized by acute diarrhoea. Administration of Saccharomyces boulardii
in combination or not with an antibiotherapy has shown to decrease significantly the duration and the frequency of diarrhoea. Experimental studies have elucidated partially the molecular mechanisms triggered to improve the host health. The discovery of its anti-inflammatory and immuno-modulatory activities in correlation with the advances in the understanding of mucosal immunology opens a new field of perspectives in Saccharomyces boulardii
Free full text review at Saccharomyces boulardii effects on gastrointestinal diseases
Further reading on probiotic microorganisms: Lactobacillus Molecular Biology: From Genomics to Probiotics
Labels: probiotics, Saccharomyces, yeast
Lactic Acid Bacteria Conference
The 9th Symposium on Lactic Acid Bacteria (LAB9) will open soon (August 31st) in the Congress Centre “Hotel Zuiderduin”, Zeeweg 52, Egmond aan Zee, the Netherlands. The 9th Symposium programme will involve a limited number of plenary invited lectures covering state-of-the-art developments with attention on Systems Biology, Evolution and Health, as well as a larger number of plenary or parallel short lectures. Besides scientists working on LAB, key note lecturers from outside the LAB field will give stimulatory talks on subjects that are of emerging interest and importance for the LAB. Evening thematic sessions on topics of specific interest will take place.
Poster contributions in all areas of research on Lactic Acid Bacteria, especially also on industrial applications are encouraged. There will be ample time for poster viewing and the posters will be on display during the whole symposium.
Finally, there will be several plenary sessions during which a number of selected posters will be explained briefly.Further information
More microbiology conferences: Microbiology Conference
Further reading: Lactobacillus Molecular Biology: From Genomics to Probiotics
Labels: lactic acid bacteria, lactobacillus, probiotics
Probiotics With Anti-Cancer Activities
from Chandra Iyer and James Versalovic
Beneficial bacteria include Lactobacillus
spp. and other lactic acid bacteria (LAB) commonly known as probiotics. LAB possesses numerous potential therapeutic properties including anti-inflammatory and anti-cancer activities and other features of interest. In recent years, studies with in vitro cell culture and animal models that clearly demonstrated protective effects of LAB for anti-tumor and anti-cancer effects. Dietary administration of LAB alleviated the risks of certain types of cancers and suppressed colonic tumor incidence, volume and multiplicity induced by various carcinogens in different animal models. Oral administration of LAB effectively reduced DNA adduct formation, ameliorated DNA damage and prevented putative preneoplastic lesions such as aberrant crypt foci induced by chemical carcinogens in the gastrointestinal (GI) tract of various animal models. LAB also increased the latency period and survival rates in test animals when challenged with carcinogenic agents. Reports also indicated that LAB cultures administered to animals inhibited liver, colon, bladder and mammary tumors, highlighting potential systemic effects of probiotics with anti-neoplastic activities.
Further reading: Lactobacillus Molecular Biology: From Genomics to Probiotics
Labels: Bifidobacterium, cancer, lactic acid bacteria, lactobacillus, probiotics
Probiotic lactobacillus may alleviate hay fever
Scientists at the Institute of Food Research
, Norwich UK found that probiotic bacteria in a daily drink can modify the immune system's response to grass pollen. Volunteers with a history of seasonal hay fever drank a daily milk drink with or without live Lactobacillus casei
over 5 months. The study was double-blinded and placebo controlled, so neither the volunteers nor the scientists knew who had been assigned the probiotic drinks.
Blood samples were taken before the grass pollen season, then again when it was at its peak (June), and 4 weeks after the end of season. There were no significant differences in levels of IgE in the blood between the two groups at the start of the study, but IgE levels were lower in the probiotic group both at the peak season and afterwards. IgE stimulates the release of histamine which produces the symptoms of hayfever.
Further reading: Lactobacillus Probiotics
Labels: bacteriology, biotechnology, lactic acid bacteria, lactobacillus, probiotics