

Publisher: Caister Academic Press
Editors: David J. Galas Keck Graduate Institute, Claremont, CA 91711, USA and Stephen J. McCormack AlleCure, Valencia, CA 91355, USA
Publication date: July 2002
ISBN-10: 0-9542464-2-X
ISBN-13: 978-0-9542464-2-6
Price: GB £159 or US $319 (hardback)
Pages: viii + 418
Chapter abstracts . Book reviews . How to Order
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The chapters in this book reflect the range of technical advances and their applications that are currently transforming biology. Topics covered include the application of computational methods, the robotics of modern automation methodologies, the new chemical and imaging methods that reveal chromosome structure and elucidate gene function, and the emergence of evolutionary and functional information by comparative genomics. Eminent international scientists describe in detail the new technology necessary to study the entire genome in a holistic manner and all the high throughput and large-scale experimental methodologies currently being used in genomic science. In addition the authors describe the progress of the newest technologies that are currently being developed. Written by experts in the field, this concise yet informative volume covers all aspects of technology pertaining to genomic studies. An essential book for anyone involved in genomic science.
Readership: bioscientists, molecular biologists, biotechnologists, geneticists, human, animal and plant geneticists, microbiologists, genome scientists. An essential book for anyone involved in genomic science.
Reviews:
"This book provides a very comprehensive review on numerous comtemporary genomics technologies and tools by a team of experts in the field. Very informative for getting a quick comparison of different technologies!" Y.F. Leung from Functional Genomics.
"The chapters in this book reflect the range of technical advances that have, and are presently, transforming the way we perform genomic analyses in the lab ... Topics covered in this book are generally well covered and clearly explained, plus each chapter contains a helpful further reading section. This book ... would be of general interest to anyone working within the genomic technology field." from Microbiology Today (2003) 30: 48.
"On balance, I liked this book. ... if you're looking for twelve diverse and generally well-written reviews bound into one volume, this will do nicely." from Human Genetics (2003) 113: 193.
"... this volume provides useful information about both current and emerging genomic technologies ... this is a good quality production; the presentation of the text is easy to the eye, broken up by a sufficient number of illustrations. A useful introduction to genomic technologies for anyone from graduate students to researchers." from The Biochemist (April 2003) .
"The Functional Genomics Series describes the state-of-the-art of technical means to efficiently analyse sequence information - provided by the nascent disciplines of bioinformatics and computational biology - and the need to fit the genomic pieces into the puzzle of biological function, resulting in an understanding of the functioning of complex systems of genes and macromolecules." from International Microbiology (2003) 6: 75-78.
" ... describes in detail the new technologies available for studying the whole-genomes of organisms ranging from microbes to humans." from International Microbiology (2003) 6: 75-78.
Key Features:
* Detailed Discussions of Cutting Edge Technologies * International Contributors * Useful Index * Up-To-Date * Broad Coverage * Expert Authors
Chapter List:
Chapter 1
An Historical Perspective on Genomic Technologies
David J. Galas and Stephen J. McCormack
Chapter 2
Molecular Cytogenetics and Human Genome Function
Pierre P. Massion and Joe W. Gray
Chapter 3
Genome Comparison Techniques
Lisa Stubbs
Chapter 4
Impact of Transgenic Technologies on Functional Genomics
Cooduvalli S. Shashikant and Frank H. Ruddle
Chapter 5
Present and Future Tags and Labels in High Throughput Genomic Analysis
Jeffrey Van Ness
Chapter 6
MAGIChip: Properties and Applications in Genomic Studies
Alexander Kolchinsky and Andrei Mirzabekov
Chapter 7
Mass Spectrometry of Nucleic Acids
Zhaojing Meng and Patrick A. Limbach
Chapter 8
Detection of Single Nucleotide Polymorphisms
Pui-Yan Kwok
Chapter 9
Live Cell Assays: Tools for Functional Genomics
Gregory W. Henkel
Chapter 10
Automation and Robotics in Genomics Laboratories
Theodore E. Mifflin, Steven D. Hamilton, Gary W. Kramer, and Robin A. Felder
Chapter 11
Computational DNA Sequence Analysis and Annotation
Hyatt, D. and Uberbacher, E.C.
Chapter 12
Beyond Sequence Similarity, or Sequence Analysis in the Age of the Genome
Itai Yanai, Adnan Derti and Charles DeLisi
(EAN: 9780954246426 Subjects: [genomics] [molecular microbiology] [bioinformatics] [molecular biology])