Published: 2010 ISBN: 978-1-904455-55-4
Price: GB £159 or US $310
Written by the top retroviral specialists, this book reviews the genomics, molecular biology, and pathogenesis of these important viruses, comprehensively covering all the recent advances. Topics include: host and retroelement interactions, endogenous retroviruses, retroviral proteins and genomes, viral entry and uncoating, reverse transcription and integration, transcription, splicing and RNA transport, pathogenesis of oncoviral infections, pathogenesis of immunodeficiency virus infections, retroviral restriction factors molecular vaccines and correlates of protection, gammaretroviral and lentiviral vectors, non-primate mammalian and fish retroviruses, simian exogenous retroviruses, and HTLV and HIV. read more ...
Published: 2010 ISBN: 978-1-904455-56-1
Price: GB £159 or US $310
In this book, expert RNAi specialists from around the world have teamed up to produce a timely and thought-provoking review of the area. The two central themes are the latest findings on RNAi-virus interactions and the current progress in the development of RNAi-based antiviral therapeutics. A number of chapters explain general concepts concerned with the role of RNAi in natural antiviral defense mechanisms, other chapters discuss how to improve the efficacy and safety of RNAi-based antiviral drugs, while others describe how this technology is being developed as a new therapeutic tool for fighting specific viruses, including HIV, HCV and respiratory viruses. Authors also outline potential new avenues for research thus providing a stimulus for further research. read more ...
Published: 2010 ISBN: 978-1-904455-52-3
Price: GB £159 or US $310
The current state-of-the-art of environmental microbiology with an emphasis on molecular biology and genomics. A range of technologies and their applications in environmental microbiology. The book focuses on the microbial diversity and phylogeny of microorganisms in the environment and describes the molecular toolbox currently available for the study of the composition and diversity of microbial communities and their functions. Also covers the application of these approaches in various environments including soil, marine water, plants, humans and wastewater treatment. read more ...
Published: 2010 ISBN: 978-1-904455-54-7
Price: GB £159 or US $310
The diverse and multiple aspects of metagenomics and the multiplicity of its potential applications. The new theoretical insights, the more recent applications, and the dynamically developing methods of data acquisition and analysis. Essential reading for all researchers wishing to broaden their knowledge of metagenomics and highly recommended for those new to the field. read more ...
Published: 2010 ISBN: 978-1-904455-53-0
Price: GB £159 or US $310
In this book leading Aspergillus researchers review and summarise the most important aspects of Aspergillus molecular biology and genomics. The book opens with a fascinating overview of the genus Aspergillus. This is followed by in-depth reviews of the Aspergillus molecular systematics, comparative genomics, bioinformatics and systems biology of Aspergillus, transcriptional regulation, genetics and genomics of sexual development of A. nidulans, genomics and secondary metabolism, ecology, development and gene regulation in A. flavus, functional systems biology, and novel industrial applications of A. oryzae genomics. Essential reading for everyone with an interest in Aspergillus and related fungi. read more ...
Published: 2009 ISBN: 978-1-904455-41-7
Price: GB £150 or US $310
A major new reference for all medical researchers, dairy technologists, microbiologists and biotechnologists in the academic and industrial sectors. Written by an international team of scientists the volume focuses on recent research on the molecular biology and genomics of Lactobacillus. Topics covered include phylogenetics, taxonomy, comparative genomics, functional genomics, the intestinal microflora, surface proteins, stress responses, interaction with the immune system, probiotics, anti-cancer potential, and much more. Essential reading for all scientists involved with lactic acid bacteria or probiotic research and a recommended book for all microbiology laboratories. read more ...
Published: 2009 ISBN: 978-1-904455-36-3
Price: GB £150 or US $310
Describes in detail the use of microorganisms for the production of the most important biopolymers and polymer precursors. The authors describe, in depth, the biosynthetic pathways, physical properties and industrial production processes and discuss in detail the genetic and metabolic engineering of microorganisms for biopolymer production. Also highlighted are the applications and potential applications of the biopolymers and microbial biotechnology read more ...
Published: 2009 ISBN: 978-1-904455-38-7
Price: GB £150 or US $310
In this book internationally recognised Clostridium experts critically review the most important aspects of clostridial research, providing the first coherent picture of the organism's molecular and cellular biology in this post-genomic era. The first major focus of the book is the genetics and molecular biology of the major clostridial toxins including: botulinum and tetanus neurotoxins, C. difficile large exotoxins, C. perfringens enterotoxin, pore-forming and binary bacterial toxins. Other topics include: molecular epidemiology of C. botulinum and C. difficile, metabolic networks in C. acetobutylicum, development of genetic knock-out systems for clostridia, surface structures, anti tumor potential of clostridia, and antibiotic resistance determinants in C. difficile. read more ...
Published: 2009 ISBN: 978-1-904455-40-0
Price: GB £150 or US $310
A critical review of the current and most recent advances in the genomics and molecular biology of mycobacteria. Focuses on the topical and most relevant aspects. Includes strain variation and evolution, hypervirulent strains, electron transport and respiration, lipid biosynthesis, DNA repair, oxygen signaling, sulphur metabolism, protein secretion, the protein kinase family. read more ...
Published: 2009 ISBN: 978-1-904455-37-0
Price: GB £150 or US $310
In this book, internationally acclaimed experts review the most important developments providing an invaluable, up-to-date summary of the molecular biology and genomics of plant pathogenic bacteria. The book opens with two chapters on bacterial evolution, diversity and taxonomy, topics that have been transformed by molecular biology and genomics analyses. The third chapter delves into the crucially understudied area of pathogen adaptation to the plant apoplast environment. The following seven chapters focus on specific plant pathogens: Agrobacterium, Leifsonia, Pectobacterium, Pseudomonas, Ralstonia, Xanthomonas, and Xylella. The next four chapters review specific, intensively studied areas of research in the plant pathogen field: microbe associated molecular patterns (MAMPs) and innate immunity; use of bacterial virulence factors to suppress plant defence; cyclic di-GMP signalling and the regulation of virulence; and plasmids and the spread of virulence. The final chapter covers the critical area of bioinformatics. read more ...
Published: 2008 ISBN: 978-1-904455-23-3
Price: GB £150 or US $300
The molecular mechanisms and biological processes in which epigenetic modifications play a primordial role are described in detail. read more ...
Published: 2008 ISBN: 978-1-904455-17-2
Price: GB £150 or US $300
Expert international authors critically review all of the most important topics in this exciting field. Although other books covering this are currently available, this book is unique in that it is the first to review the area from a molecular biology and genomics perspective. Topics covered include: aerobic and anaerobic biodegradation of aromatic compounds, molecular detection methods e.g. microautoradiography, mRNA analyses, etc., genome-based predictive modelling, elucidation of regulatory networks, bioavailability, chemotaxis and transport issues, functional genomic analyses, natural attenuation, community fingerprinting and metagenomics, biotreatment, and biocatalysts engineering. Essential reading for microbial degradation and bioremediation scientists and of general interest for microbiologists working in field of environmental microbiology. read more ...
Published: 2008 ISBN: 978-1-904455-33-2
Price: GB £150 or US $310
In this book leading V. cholerae experts, the chapters review the most important cutting-edge genetic facets of V. cholerae including its genomic organization, population genetics, molecular epidemiology, and synchronized regulation of gene expression. Other topics include the molecular basis for enhanced transmissibility of cholera during epidemics, survival of the pathogen in the environment, and above all the evolution of the species to attain increased fitness both as a pathogen and an environmental organism. Essential reading for everyone with an interest in Vibrio and recommended reading for other scientists working in microbial pathogenesis, microbial genomics and antimicrobial research. read more ...
Published: 2008 ISBN: 978-1-904455-21-9
Price: GB £150 or US $300
This timely book brings together all of the key recent research on this disparate group of viruses, providing for the first time a single resource reviewing dsRNA viral structure and molecular biology. Written by well respected and experienced virologists, topics include: the structures of orthoreoviruses, rotavirus, phytoreoviruses, and bluetongue virus, entry into the bacterial cell, crystal structure of reovirus polymerase λ3, assembly of the reovirus genome, genomic RNA packaging and replication in the Cystoviridae, and much more. Essential reading for all dsRNA virologists and all other virologists with an interest in molecular and structural biology. read more ...
Published: 2008 ISBN: 978-1-904455-26-4
Price: GB £150 or US $300
The current state of many of the most critical features of Legionella. Authors have contributed papers describing and discussing the latest research findings with an emphasis on molecular aspects. Recommended for all microbiology and clinical research laboratories. read more ...
Published: 2008 ISBN: 978-1-904455-24-0
Price: GB £150 or US $300
The molecular biology of micro-organisms involved in the two major dental diseases: caries and periodontal disease. Research has focused on factors which might modulate the interaction between the resident oral bacteria and the host. read more ...
Published: 2008 ISBN: 978-1-904455-29-5
Price: GB £150 or US $300
This volume, the first to focus on the stapyhlococcal genetics provides a state-of-the art overview of the field. Topics include the sequencing projects, including spin-off microarray and systems biology tools, epidemiology, evolution, manipulation of the genome, diagnostics, gene expression due to global regulators and environmental triggers, cell-wall synthesis, coagulase-negative species, and animal pathogens. It is designed for two major audiences. Firstly, to introduce the subject to new researchers, including those unfamiliar with genetics. Secondly, for established researchers, for whom it will serve as an invaluable reference and summary of a large field, as well as presenting the latest advances and future trends written by those who are developing them. read more ...
Published: 2008 ISBN: 978-1-904455-34-9
Price: GB £150 or US $310
Pasteurella book. In this timely book, leading international Pasteurellaceae scientists critically review the most important current research providing an up-to-date review of the molecular biology, genomics and virulence of these fascinating organisms. Topics covered include taxonomy and biodiversity, phylogeny, comparative genomics, competence, DNA uptake and transformation, proteomics and protein secretion, RTX toxins, lipopolysaccharides, biofilms, quorum sensing, antimicrobial resistance, diagnosis, and OMP and iron uptake. Each chapter is independent and can be read in isolation and as a whole the book provides an important resource summarising our current knowledge of Pasteurellaceae genomics and molecular biology. Essential reading for everyone working on Pasteurellaceae and related organisms. read more ...
Published: 2008 ISBN: 978-1-904455-25-7
Price: GB £150 or US $300
Experts in RNA research explore and discuss the methods whereby RNA can regulate gene expression with examples in yeast, Drosophila, mammals, and viral infection, and highlight the application of this knowledge in therapeutics and research. read more ...
Published: 2008 ISBN: 978-1-904455-20-2
Price: GB £150 or US $300
Expert international authors have contributed chapters on diverse topics including taxonomy, lipopolysaccharides, catabolism of aromatic compounds, transformation systems, transcriptional regulation, applications in biotechnology, the molecular basis for virulence and pathogenicity, molecular epidemiology, and antibiotic resistance. This book is highly recommended for anyone involved in Acinetobacter research. read more ...
Published: 2008 ISBN: 978-1-904455-27-1
Price: GB £150 or US $300
Archaea: New Models for Prokaryotic Biology | Book Archaea: New Models for Prokaryotic Biology book, the authors present an expanding pattern of new information relevant to both the general and the technical reader. The book focuses on molecular biology and genomics and topics include the biology of metals, redox chemistry, respiration, sugar catabolism, nucleic acid modification, DNA replication, repair and recombination, transcriptomics, signal transduction and peptide antibiotics. Throughout read more ...
Published: 2008 ISBN: 978-1-904455-19-6
Price: GB £150 or US $300
This concise volume reviews the most current and topical aspects of Pseudomonas molecular biology and genomics and is aimed at a readership of research scientists, graduate students and other specialists. Renowned international authors have contributed chapters on diverse topics including taxonomy, genome diversity, oligonucleotide usage, polysaccharides, pathogenesis, virulence, biofilms, antibiotic resistance and iron uptake. In addition an entire chapter is devoted to the genetic tools being developed to take full advantage of the wealth of information generated by the genome sequencing efforts. read more ...
Published: 2008 ISBN: 978-1-904455-28-8
Price: GB £150 or US $300
In this book, internationally recognised Leishmania experts critically review the most important aspects of current Leishmania research, providing the first coherent picture of the organism's molecular and cellular biology since the publication of the genome sequence. Chapters are written from a molecular and genomic perspective and discuss in depth Leishmania-specific aspects of trypanosomatid biology and pathology. Topics include: diagnosis and epidemiology, genome structure and content, regulation of gene expression, the Leishmania proteome, the Leishmania metabolome, Leishmania differentiation, interaction with the sand fly vector, drug discovery, drug resistance, and much more. Essential reading for all researchers working with Leishmania, trypanosomes and protozoa. A recommended book for all biology and medical libraries. read more ...
Published: 2008 ISBN: 978-1-904455-15-8
Price: GB £150 or US $300
This volume brings together the expertise and enthusiasm of an international panel of leading cyanobacterial researchers to provide a state-of-the art overview of the field. Topics covered include: evolution, comparative genomics, gene transfer, molecular ecology and environmental genomics, stress responses, bioactive compounds, circadian clock, structure of the photosynthetic apparatus, membrane systems, carbon acquisition, nitrogen assimilation and C/N balance sensing and much more. Essential for anyone with an interest in cyanobacteria, bacterial photosynthesis, bacterial nitrogen fixation, and symbosis. read more ...
Published: 2008 ISBN: 978-1-904455-31-8
Price: GB £150 or US $310
Helicobacter is leading cause of peptic ulcers, gastritis and gastric cancer worldwide, therefore has been the subject of intensive research. As the number of publications in this field has risen dramatically in recent years, it is extremely difficult for even the most diligent reader to stay abreast of progress. This book distills the most important cutting-edge findings in the field to produce a timely and comprehensive review. With contributions from leading international helicobacter researchers, topics include: lipopolysaccharides, outer membrane proteins, motility and chemotaxis, type IV secretions systems, metal metabolism, molecular mechanisms of host adaptation, genomotyping, and proteonomics. read more ...
Published: 2008 ISBN: 978-1-904455-30-1
Price: GB £150 or US $310
Leading Corynebacteria experts provide a description of the current state-of-the-art molecular biology toolbox available for Corynebacterium research, including global analyses techniques such as comparative genomics, transcriptome, proteome and metabolome analysis as well as the most recent knowledge on Corynebacterium promoter structures and vector systems. Furthermore, topics such as regulatory networks controlling carbon, nitrogen, phosphorus, sulphur and iron metabolism, cell wall structure, proteolysis and environmental stress response are covered. Essential reading for all Corynebacterium scientists and everyone with an interest in global analysis techniques, global regulation and systems biology. read more ...
Published: 2007 ISBN: 978-1-904455-16-5
Price: GB £150 or US $300
In this timely book, internationally renowned experts review literally every aspect of cutting edge coronavirus research providing the first coherent picture of the molecular and cellular biology since the outbreak of SARS in 2003. The book is divided into two sections: Part I focuses on the molecular biology of the virus itself and includes topics such as coronavirus binding and entry, replicase gene function, cis-acting RNA elements, coronavirus discontinuous transcription, reverse genetics, genome packaging and molecular evolution. In Part II of the book, the focus is on molecular and cellular pathogenesis and infection control. read more ...
Published: 2007 ISBN: 978-1-904455-14-1
Price: GB £150 or US $300
Written by eminent international researchers actively involved in the disparate areas of bacteriophage research this book focuses on the current rapid developments in this exciting field. The book opens with an excellent chapter that provides a broad overview of the topics and also highlights the multifaceted nature of bacteriophage research. This is followed by a series of reviews that focus on the current most cutting-edge topics including bioinformatics and genomics, phage in the environment, bacteriophage in medicine, transfer of phage DNA to the host, contribution to host phenotype and much more. read more ...
Published: 2007 ISBN: 978-1-904455-12-7
Price: GB £150 or US $300
An overview of the most recent and most exciting research providing a picture of the major cytological aspects of this model bacterium. Includes replication and segregation of the chromosome, cell division, replication and growth, the cell cycle, transcription, translation, regulation, the actin cyctoskeleton, the cell membrane and cell wall, biofilm formation and sporulation, DNA repair, the regulation of transcription through RNA molecules, and the regulation of protein activity through proteolysis. read more ...
Published: 2007 ISBN: 978-1-904455-13-4
Price: GB £150 or US $300
International experts provide comprehensive and authoritative reviews of current research on Candida. Essential reading for all Candida genome and molecular biology researchers and a recommended text for scientists working on fungal genomics and molecular biology. read more ...
Published: 2006 ISBN: 978-1-904455-07-3
Price: GB £30 or US $60
A unique PCR troubleshooting guide that is an essential companion for anyone who uses the polymerase chain reaction technique. read more ...
Published: 2004 ISBN: 978-0-9542464-6-4
Price: GB £115 or US $230
The completion of the Plasmodium falciparum genome sequence in late 2002 hearlded a new era in malaria research. The search could begin in earnest for new drugs and vaccines to combat malaria, a disease which afflicts up to 500 million people worldwide and is responsible for the deaths of more than one million people each year. More importantly, it should enable a greater understanding of the living parasite and it's interaction with the insect vector and human host. In this book internationally renown experts provide up to date reviews of the most important aspects of post-genomic malaria research. Topics covered include: the P. falciparum genome and model parasites, bioinformatics and genome databases, microsatellite analysis, analysis of chromosome structure, cell cycle to RNA polymerase I and II mediated gene expression, role of the nuclear genome, the parasite surface and cell biology, and much much more. read more ...
Published: 2003 ISBN: 978-0-9542464-4-0
Price: GB £90 or US $180
Computational biology and bioinformatics form a major, integral part of genomics. From sequence fragment assembly, to gene prediction, to prediction of protein functions and structure, to identification of regulatory signals in DNA, to building phylogenetic trees, it would not be an exaggeration to state that genomics is primarily computational. Major new programs, software and internet facilities have evolved recently that facilitate computational analysis and more novel technologies are currently being developed. Written by experts in the field, this volume highlights research on the emerging, perhaps somewhat controversial, topics in genomics and shows the feedback between the new developments and the established methods of computational biology. An essential book for anyone involved in genomic science or bioinformatics. read more ...
Published: 2002 ISBN: 978-0-9542464-3-3
Price: GB £75 or US $150
Eminent scientists have contributed comprehensive reviews on all aspects of the genomics of Rhodococcus, Mycobacteria, Streptomyces and other organisms. The authors provide an insight into the many facets of large-scale functional investigation in a variety of bacteria with the explicit goal to find common rules in the dynamic and structural organisation of these organisms. This volume is the definitive guide to current research in this increasingly important area. read more ...
Published: 2002 ISBN: 978-0-9542464-2-6
Price: GB £90 or US $180
The chapters in this book reflect the range of technical advances and their applications that are currently transforming biology. Topics covered include the application of computational methods, the robotics of modern automation methodologies, the new chemical and imaging methods that reveal chromosome structure and elucidate gene function, and the emergence of evolutionary and functional information by comparative genomics. Eminent international scientists describe in detail the new technology necessary to study the entire genome in a holistic manner and all the high throughput and large-scale experimental methodologies currently being used in genomic science. In addition the authors describe the progress of the newest technologies that are currently being developed. read more ...