Brucella: Molecular and Cellular Biology
Publisher: Horizon Bioscience
Editor: Ignacio López-Goñi and Ignacio Moriyón Universidad de Navarra, Pamplona, Spain
Publication date: 01 November 2004
ISBN-10: 1-904933-04-1
ISBN-13: 978-1-904933-04-5
Price: GB £106 or US $212 (hardback).
Pages: xiv + 432
Chapter abstracts . How to Order
Publication of the complete genome sequences of several different Brucella species has provided researchers with the opportunity to take a more directed approach to study this organism's physiology, virulence, and genetic diversity. In this book highly acclaimed Brucella scientists comprehensively review all of the most important advances in the Brucella post-genomic era providing for the first time a coherent picture of Brucella molecular and cellular biology. The book opens with chapters that focus on the development of molecular diagnostic tools and these are followed by chapters on genetic evolution and its relationship to pathogenicity. Other topics include Brucella comparative genomics and proteomics, analysis of the structure, biosynthesis and biology of glucans and lipopolysaccharides, pathogenicity, approaches to vaccine development, bacterium-host interactions, immune response, and much more. Essential reading for everyone with an interest in Brucella and brucellosis and recommended reading for the wider body of scientists with an interest in microbial diagnostics, microbial pathogenesis, cellular microbiology and immunology, and vaccine development.
Key Features:
* Detailed Discussions of Cutting Edge Topics
* Expert
International Authors
* Fully Up-To-Date
* Broad Coverage
* Comprehensive Reference Section
Reviews:
"... provides a timely, up-to-date review of the current knowledge of Brucella, linking post-genomic data with accepted dogma and highlighting current and persistent questions pondered by researchers today." from Microbiology Today (2005) August issue.
"This is a very useful volume for anyone interested in developments in brucellosis research." from Clinical Infectious Diseases (2006) 42: 439 February issue.
Chapter List:
Foreword
Chapter 1
DNA Polymorphism and Taxonomy of Brucella Species
Axel Cloeckaert and Nieves Vizcaino
Chapter 2
Molecular Diagnostics of Animal Brucellosis: A Review of PCR-Based Assays and Approaches
Betsy J. Bricker
Chapter 3
Polymerase Chain Reaction: A Powerful New Approach for the Diagnosis of Human Brucellosis
Juan D. Colmenero, María I. Queipo-Ortuño and Pilar Morata
Chapter 4
A Brucella melitensis Genomic Database
Xavier De Bolle, Christophe Lambert, Eric Depiereux and Jean-Jacques Letesson
Chapter 5
Comparative Genomics of Brucella melitensis, B. suis, and B. abortus
Shirley M. Halling, Cynthia Gibas and Stephen Boyle
Chapter 6
Comparative Proteomics of Brucellae Species
Vito G. DelVecchio and Cesar V. Mujer
Chapter 7
Brucella Virulence: A Matter of Control
Jean-Jaques Letesson and Xavier De Bolle
Chapter 8
Brucella Lipopolysaccharide: Structure, Biosynthesis and Genetics
Maite Iriarte, David González, Rose M. Delrue, Daniel Monreal, Raquel Conde, Ignacio López-Goñi, Jean-Jacques Letesson, and Ignacio Moriyón
Chapter 9
Brucella Cyclic b-1,2-Glucans: Structure, Biosynthesis, Biological Activities and Role in Virulence
Nora Iñón de Iannino and Rodolfo A. Ugalde
Chapter 10
The Brucella bvrS/bvrR and Related Two-Component Regulatory Systems of the a-2 Proteobacteria: Common Regulatory Strategies of Animal and Plant Pathogens and Endosymbionts.
Ignacio López-Goñi, Lorea Manterola and Shen Q. Pan
Chapter 11
Erythritol Metabolism and Virulence in Brucella
Juan M. García-Lobo and Félix Sangari García
Chapter 12
Iron Metabolism in Brucella
R. Martin Roop II, Bryan H. Bellaire, Eric Anderson and James T. Paulley
Chapter 13
Brucella Interaction with Membrane Lipids of the Host Cell
Masahisa Watarai
Chapter 14
Invasion, Intracellular Trafficking and Replication of Brucella Organisms in Professional and Non-Professional Phagocytes
Edgardo Moreno and Jean-Pierre Gorvel
Chapter 15
The Intramacrophagic Environment of Brucella spp. and Their Replicative Niche
Véronique Jubier-Maurin, Séverine Loisel, Jean-Pierre Liautard, and Stephan Köhler
Chapter 16
Host Cellular Immune Responses Against Brucella spp. Evaluated Using the Mouse Model
Cynthia L. Baldwin and Radhika Goenka
Chapter 17
Development of New Brucella Vaccines by Molecular Methods
David L. Hoover, Mikeljon P. Nikolich, Mina J. Izadjoo, Richard H. Borschel, and Apurba K. Bhattacharjee
Chapter 18
Alternative Ovine Brucellosis Vaccine: Experiences with Drug Delivery Systems
Carlos Gamazo, Maite Estevan, Maribel Murillo, M. Jesús Grilló, Clara M. Marín, Montserrat Barberán, M. Mar Goñi, José M. Blasco, and Juan M. Irache
(EAN: 9781904933045)
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