New and Forthcoming books Other books 2010 2009 2008 2007 2006 New Books newsletter
Retroviruses: Molecular Biology, Genomics and Pathogenesis ISBN: 978-1-904455-55-4 Price: £159
Edited by: Reinhard Kurth and Norbert Bannert
Written by the top retroviral specialists, this book reviews the genomics, molecular biology, and pathogenesis of these important viruses, comprehensively covering all the recent advances. Topics include: host and retroelement interactions, endogenous retroviruses, retroviral proteins and genomes, viral entry and uncoating, reverse transcription and integration, transcription, splicing and RNA transport, pathogenesis of oncoviral infections, pathogenesis of immunodeficiency virus infections, retroviral restriction factors molecular vaccines and correlates of protection, gammaretroviral and lentiviral vectors, non-primate mammalian and fish retroviruses, simian exogenous retroviruses, and HTLV and HIV. Essential reading for every retrovirologist and a recommended text for all virology and molecular biology laboratories.
Coming soon ... ! Full information at Retroviruses: Molecular Biology, Genomics and Pathogenesis.
Metagenomics: Theory, Methods and Applications ISBN: 978-1-904455-54-7 Price: £159
Edited by: Diana Marco
The diverse and multiple aspects of metagenomics and the multiplicity of its potential applications. Renowned authors from around the world have contributed chapters covering the new theoretical insights, the more recent applications, and the dynamically developing methods of data acquisition and analysis. Topics include: Conceptual frameworks, tools and methods, complementary approaches, horizontal gene transfer, complex microbial communities, public data resources, plant-microbe interactions, bioremediation, industrial bioproducts, archaeal metagenomics, bioprospecting novel genes, the human microbiome, and philosophical themes in metagenomics.
Coming soon ... ! Full information at Metagenomics: Theory, Methods and Applications.
Aspergillus: Molecular Biology and Genomics ISBN: 978-1-904455-53-0 Price: £159
Edited by: Masayuki Machida and Katsuya Gomi
Leading Aspergillus researchers review and summarise the most important aspects of Aspergillus molecular biology and genomics. Topics include an overview of the genus Aspergillus, in-depth reviews of the Aspergillus molecular systematics, comparative genomics, bioinformatics and systems biology of Aspergillus, transcriptional regulation, genetics and genomics of sexual development of A. nidulans, genomics and secondary metabolism, ecology, development and gene regulation in A. flavus, functional systems biology, and novel industrial applications of A. oryzae genomics.
Coming soon ... ! Full information at Aspergillus: Molecular Biology and Genomics.
Environmental Molecular Microbiology ISBN: 978-1-904455-52-3 Price: £159
Edited by: Wen-Tso Liu and Janet K. Jansson
The current state-of-the-art of environmental microbiology with an emphasis on molecular biology and genomics. A range of technologies and their applications in environmental microbiology. The book focuses on the microbial diversity and phylogeny of microorganisms in the environment and describes the molecular toolbox currently available for the study of the composition and diversity of microbial communities and their functions. Also covers the application of these approaches in various environments including soil, marine water, plants, humans and wastewater treatment.
Coming soon ... ! Full information at Environmental Molecular Microbiology.
Neisseria: Molecular Mechanisms of Pathogenesis ISBN: 978-1-904455-51-6 Price: £150
Edited by: Caroline Genco and Lee Wetzler
A comprehensive update on the current understanding of the molecular mechanisms of pathogenesis in Neisseria. Leading authorities have contributed chapters on topics such as gene expression, genomics, biofilms, denitrification, adhesion strategies, mechanisms of cellular invasion, inate immunity, complement, apoptosis, acquired immunity, vaccine development, epidemiology and antibiotic resistance.
Coming soon ... ! Full information at Neisseria: Molecular Mechanisms of Pathogenesis.
Frontiers in Dengue Virus Research ISBN: 978-1-904455-50-9 Price: £150
Edited by: Kathryn A. Hanley and Scott C. Weaver
A timely review of the rapidly expanding dengue research literature and a stimulus for future research. Topics include: evolutionary history, epidemiology, translation and processing of the viral polyprotein, viral replication, the role of the viral untranslated regions, pathogenesis, host response to DENV, development of animal models, DENV-mosquito interactions, dynamics of dengue virus transmission, emergence of DENV from its ancestral, sylvatic cycle, vaccines, novel anti-dengue drugs and passive immunotherapy.
Coming soon ... ! Full information at Frontiers in Dengue Virus Research.
ABC Transporters in Microorganisms ISBN: 978-1-904455-49-3 Price: £150
Edited by: Alicia Ponte-Sucre
Describes the latest, up-to-date theory, methodology and applications of ABC transporters in microorganisms. The topics include the structure, physiology and evolution of ABC transporters, as well as their special characteristics in specific microorganisms including bacteria, yeast, trypanosomes and malaria parasites. Includes the role of ABC transporters in the design of strategies to circumvent drug resistance in microorganisms.
Coming soon ... ! Full information at ABC Transporters in Microorganisms: Research, Innovation and Value as Targets against Drug Resistance.
Pili and Flagella: Current Research and Future Trends ISBN: 978-1-904455-48-6 Price: £150
Edited by: Ken Jarrell
This book, the first for many years on this important topic, brings together some of the top scientists in the field and describes the current knowledge and latest research on prokaryotic pili and flagella. The emphasis of the chapters is on the molecular biology, genetics, structure, assembly and function of these structures.
Available now ... ! Full information at Pili and Flagella: Current Research and Future Trends .
Lab-on-a-Chip Technology (Vol. 2): Biomolecular Separation and Analysis ISBN: 978-1-904455-47-9 Price: £150
Edited by: Keith E. Herold and Avraham Rasooly
A comprehensive volume focusing on the applications of LOC technology in the biomedical and life sciences. A skillful selection of topics of exceptional importance to current science ensures that this book will be of major value to a wide range of molecular biologists, clinical scientists, microbiologists, biochemists and anyone interested in LOC technology or developing applications for LOC devices.
Available now ... ! Full information at Lab-on-a-Chip Technology: Biomolecular Separation and Analysis .
Lab-on-a-Chip Technology (Vol. 1): Fabrication and Microfluidics ISBN: 978-1-904455-46-2 Price: £150
Edited by: Keith E. Herold and Avraham Rasooly
This comprehensive volume presents the current technologies in the field and includes theoretical and technical information to enable both the understanding of the technology and the reproduction of experiments. The book aims to help the reader to understand current LOC technologies, to perform similar experiments, to design new LOC systems and to develop new methodologies and applications.
Available now ... ! Full information at Lab-on-a-Chip Technology: Fabrication and Microfluidics.
Bacterial Polysaccharides: Current Innovations and Future Trends ISBN: 978-1-904455-45-5 Price: £150
Edited by: Matthias Ullrich
Experienced and authoritative experts review the most important innovations in research on and biotechnological applications of bacterial polysaccharides. An interdisciplinary view that examines bacterial polysaccharides from molecular biology, genome-, transcriptome- and proteome-wide perspectives, and looks at the ecological aspects and systems biology approaches. Covers the applications of bacterial polysaccharides in medicine, the food industry, and renewable energy production.
Available now ... ! Full information at Bacterial Polysaccharides.
Microbial Toxins: Current Research and Future Trends ISBN: 978-1-904455-44-8 Price: £150
Edited by: Thomas Proft
This timely volume serves as an update on the most important recent advances. Written by internationally respected scientists, topics reviewed include: toxins carried by mobile genetic elements, botulinum neurotoxins, anthrax, subtilase cytotoxin, Pasteurella multocida toxin, RTX toxins of vibrios, vacA toxin, staphylococcal immune evasion toxins and fungal ribotoxins.
Available now ... ! Full information at Microbial Toxins.
Acanthamoeba: Biology and Pathogenesis ISBN: 978-1-904455-43-1 Price: £150
Author: Naveed Khan
The first comprehensive review of Acanthamoeba research to be published. Everything that is known about Acanthamoeba is critically reviewed and divided into easy-to-follow sections. This book presents the current state of research on every aspect of this organism, detailing recent advances. This book is the definitive guide to current research on this increasingly important organism.
Available now ... ! Full information at Acanthamoeba.
Bacterial Secreted Proteins: Secretory Mechanisms and Role in Pathogenesis ISBN: 978-1-904455-42-4 Price: £150
Edited by: Karl Wooldridge
A broad and in-depth description of the current knowledge of bacterial protein secretion and its role in pathogenesis. This publication on bacterial secreted proteins, the secretory systems of bacteria and the vital role of secreted proteins in bacterial pathogenesis is aimed at microbiologists, molecular biologists, public health scientists and researchers engaged in the study of pathogenesis, drug design and vaccine development.
Available now ... ! Full information at Bacterial Secreted Proteins.
Lactobacillus: Molecular Biology ISBN: 978-1-904455-41-7 Price: £150
Edited by: Åsa Ljungh and Torkel Wadström
This major new work focuses on recent research on the molecular biology and genomics of Lactobacillus. Written by an international team of scientists the volume is an essential reference for all dairy technologists, microbiologists and biotechnologists in the academic and industrial sectors. Topics covered include phylogenetics, taxonomy, comparative genomics, functional genomics, the intestinal microflora, surface proteins, stress responses, interaction with the immune system, probiotics, anti-cancer potential, and much more. Essential reading for all scientists involved with lactic acid bacteria or probiotic research and a recommended book for all microbiology laboratories.
Available now ... ! Full information at Lactobacillus: Molecular Biology.
Mycobacterium: Genomics and Molecular Biology ISBN: 978-1-904455-40-0 Price: £150
Edited by: Tanya Parish and Amanda Brown
Expert scientists critically review the current and most recent advances in the genomics and molecular biology of mycobacteria. The focus is on the topical and most relevant aspects and the authors aim to give readers an insight into the current understanding of the subject and the future direction of research. Topics covered include strain variation and evolution, hypervirulent strains, electron transport and respiration, lipid biosynthesis, DNA repair, oxygen signaling, sulphur metabolism, protein secretion, the protein kinase family, and much more..
Available now ... ! Full information at Mycobacterium: Genomics and Molecular Biology.
Real-Time PCR: Current Technology and Applications ISBN: 978-1-904455-39-4 Price: £150
Edited by: Julie Logan, Kirstin Edwards and Nick Saunders
This essential manual presents a comprehensive guide to the most up-to-date technologies and applications as well as providing an overview of the theory of this increasingly important technique. Renowned experts in the field describe and discuss the latest PCR platforms, fluorescent chemistries, validation software, data analysis, and internal and external controls. This timely and authoritative volume also discusses a wide range of RT-PCR applications including: clinical diagnostics, biodefense, RNA expression studies, validation of array data, mutation detection, food authenticity and legislation, NASBA, molecular halotyping, and much more..
Available now ... ! Full information at Real-Time PCR: Current Technology and Applications.
Clostridia: Molecular Biology in the Post-genomic Era ISBN: 978-1-904455-38-7 Price: £150
Edited by: Holger Brüggemann and Gerhard Gottschalk
Internationally recognised Clostridium experts critically review the most important aspects of clostridial research, providing the first coherent picture of the organism's molecular and cellular biology in this post-genomic era. The first major focus of the book is the genetics and molecular biology of the major clostridial toxins including: botulinum and tetanus neurotoxins, C. difficile large exotoxins, C. perfringens enterotoxin, pore-forming and binary bacterial toxins. Other topics include: molecular epidemiology of C. botulinum and C. difficile, metabolic networks in C. acetobutylicum, development of genetic knock-out systems for clostridia, surface structures, anti tumor potential of clostridia, and antibiotic resistance determinants in C. difficile.
Available now ... ! Full information at Clostridia: Molecular Biology in the Post-genomic Era.
Plant Pathogenic Bacteria: Genomics and Molecular Biology ISBN: 978-1-904455-37-0 Price: £150
Edited by: Robert W. Jackson
Acclaimed experts review the most important developments providing an invaluable, up-to-date summary of the molecular biology and genomics of plant pathogenic bacteria. The book opens with two chapters on bacterial evolution, diversity and taxonomy, topics that have been transformed by molecular biology and genomics analyses. The third chapter delves into the crucially understudied area of pathogen adaptation to the plant apoplast environment. The following seven chapters focus on specific plant pathogens: Agrobacterium, Leifsonia, Pectobacterium, Pseudomonas, Ralstonia, Xanthomonas, and Xylella. The next four chapters review specific, intensively studied areas of research in the plant pathogen field: microbe associated molecular patterns (MAMPs) and innate immunity; use of bacterial virulence factors to suppress plant defence; cyclic di-GMP signalling and the regulation of virulence; and plasmids and the spread of virulence. The final chapter covers the critical area of bioinformatics.
Available now ... ! Full information at Plant Pathogenic Bacteria: Genomics and Molecular Biology.
Microbial Production of Biopolymers and Polymer Precursors: Applications and Perspectives ISBN: 978-1-904455-36-3 Price: £150
Edited by: Bernd H. A. Rehm
Written by expert, internationally renowned scientists, this comprehensive volume describes in detail the use of microorganisms for the production of the most important biopolymers and polymer precursors. The authors describe, in depth, the biosynthetic pathways, physical properties and industrial production processes and discuss in detail the genetic and metabolic engineering of microorganisms for biopolymer production. Also highlighted are the applications and potential applications of the biopolymers and microbial biotechnology.
Available now ... ! Full information at Microbial Production of Biopolymers and Polymer Precursors: Applications and Perspectives.
Plasmids: Current Research and Future Trends ISBN: 978-1-904455-35-6 Price: £150
Edited by: Georg Lipps
Written by acknowledged experts in the field, this volume provides an up to date treatment of the structure, function and application of plasmids with a particular emphasis on current and future trends. The book is aimed primarily at research scientists, graduate students and professional scientists but will also be of great interest to all molecular biologists and microbiologists involved in research or teaching. Chapters include a historical perspective on E. coli plasmids and the scientific background of the plasmids used routinely in laboratories to clone genes and to express proteins; an overview on the plasmids of archaea and eukarya; bioinformatic tools; horizontal gene transfer and the process of DNA transfer. Two entire chapters are devoted to the important medical applications of plasmids, including the correction of gene defects and vaccines to treat cancer or infectious diseases.
Available now ... ! Full information at Plasmids: Current Research and Future Trends.
Pasteurellaceae: Biology, Genomics and Molecular Aspects ISBN: 978-1-904455-34-9 Price: £150
Edited by: Peter Kuhnert and Henrik Christensen
In this timely book, leading international Pasteurellaceae scientists critically review the most important current research providing an up-to-date review of the molecular biology, genomics and virulence of these fascinating organisms. Topics covered include taxonomy and biodiversity, phylogeny, comparative genomics, competence, DNA uptake and transformation, proteomics and protein secretion, RTX toxins, lipopolysaccharides, biofilms, quorum sensing, antimicrobial resistance, diagnosis, and OMP and iron uptake. Each chapter is independent and can be read in isolation and as a whole the book provides an important resource summarising our current knowledge of Pasteurellaceae genomics and molecular biology. Essential reading for everyone working on Pasteurellaceae and related organisms.
Available now ... ! Full information at Pasteurellaceae: Biology, Genomics and Molecular Aspects.
Vibrio cholerae: Genomics and Molecular Biology ISBN: 978-1-904455-33-2 Price: £150
Edited by: Shah M. Faruque and G. Balakrish Nair
Written by leading V. cholerae experts, the chapters review the most important cutting-edge genetic facets of V. cholerae including its genomic organization, population genetics, molecular epidemiology, and synchronized regulation of gene expression. Other topics include the molecular basis for enhanced transmissibility of cholera during epidemics, survival of the pathogen in the environment, and above all the evolution of the species to attain increased fitness both as a pathogen and an environmental organism. Essential reading for everyone with an interest in Vibrio and recommended reading for other scientists working in microbial pathogenesis, microbial genomics and antimicrobial research.
Available now ... ! Full information at Vibrio cholerae: Genomics and Molecular Biology.
Pathogenic Fungi: Insights in Molecular Biology ISBN: 978-1-904455-32-5 Price: £150
Edited by: Gioconda San-Blas and Richard A. Calderone
A panel of expert international mycologists critically review the most important cutting-edge topics. Chapters are written from a molecular and genomic perspective and through the provision of extensive reference sections positively encourage readers to pursue the subject in greater detail. Topics include: gene expression and regulation, heterozygosity in Candida, molecular diagnosis, regulation of the host-fungal interaction, the development of anti-fungals, signal transduction, and mechanisms of multi-drug resistance. Essential reading for everyone with an interest in pathogenic fungi including: mycologists, biotechnologists, molecular biologists, and pharmaceutical and biotechnology companies.
Available now ... ! Full information at Pathogenic Fungi: Insights in Molecular Biology.
Helicobacter pylori: Molecular Genetics and Cellular Biology ISBN: 978-1-904455-31-8 Price: £150
Edited by: Yoshio Yamaoka
Helicobacter pylori is an important human pathogen that infects up to 50% of the human population. As the leading cause of peptic ulcers, gastritis and gastric cancer worldwide, the organism has been the subject of intensive research to unravel the mysteries of its genetics and cellular biology. In fact the number of publications in this field has risen dramatically in recent years making it extremely difficult for even the most diligent reader to stay abreast of progress. This book distills the most important cutting-edge findings in the field to produce a timely and comprehensive review. With contributions from leading international helicobacter researchers, topics include: lipopolysaccharides, outer membrane proteins, motility and chemotaxis, type IV secretions systems, metal metabolism, molecular mechanisms of host adaptation, genomotyping, and proteonomics. A useful introduction to the subject for new researchers and an invaluable reference for the experienced researcher, this book is essential reading for all researchers working with Helicobacter and related organisms.
Available now ... ! Full information at Helicobacter pylori: Molecular Genetics and Cellular Biology.
Corynebacteria: Genomics and Molecular Biology ISBN: 978-1-904455-30-1 Price: £150
Edited by: Andreas Burkovski
This volume brings together the expertise and enthusiasm of today's leading experts to provide a description of the current state-of-the-art molecular biology toolbox available for Corynebacterium research, including global analyses techniques such as comparative genomics, transcriptome, proteome and metabolome analysis as well as the most recent knowledge on Corynebacterium promoter structures and vector systems. Furthermore, topics such as regulatory networks controlling carbon, nitrogen, phosphorus, sulphur and iron metabolism, cell wall structure, proteolysis and environmental stress response are covered. Essential reading for all Corynebacterium scientists and everyone with an interest in global analysis techniques, global regulation and systems biology.
Available now ... ! Full information at Corynebacteria: Genomics and Molecular Biology.
Staphylococcus: Molecular Genetics ISBN: 978-1-904455-29-5 Price: £150
Edited by: Jodi Lindsay
This volume, the first to focus on the stapyhlococcal genetics, brings together the expertise and enthusiasm of an international panel of leading staphylococcal researchers to provide a state-of-the art overview of the field. Topics include the sequencing projects, including spin-off microarray and systems biology tools, epidemiology, evolution, manipulation of the genome, diagnostics, gene expression due to global regulators and environmental triggers, cell-wall synthesis, coagulase-negative species, and animal pathogens. It is designed for two major audiences. Firstly, to introduce the subject to new researchers, including those unfamiliar with genetics. Secondly, for established researchers, for whom it will serve as an invaluable reference and summary of a large field, as well as presenting the latest advances and future trends written by those who are developing them. Essential reading for anyone involved in Staphylococcus research.
Available now ... ! Full information at Staphylococcus: Molecular Genetics.
Leishmania: After The Genome ISBN: 978-1-904455-28-8 Price: £150
Edited by: Peter J. Myler and Nicolas Fasel
In this book, internationally recognised Leishmania experts critically review the most important aspects of current Leishmania research, providing the first coherent picture of the organism's molecular and cellular biology since the publication of the genome sequence. Chapters are written from a molecular and genomic perspective and discuss in depth Leishmania-specific aspects of trypanosomatid biology and pathology. Topics include: diagnosis and epidemiology, genome structure and content, regulation of gene expression, the Leishmania proteome, the Leishmania metabolome, Leishmania differentiation, interaction with the sand fly vector, drug discovery, drug resistance, and much more. Essential reading for all researchers working with Leishmania, trypanosomes and protozoa. A recommended book for all biology and medical libraries.
Available now ... ! Full information at Leishmania: After The Genome.
Archaea: New Models for Prokaryotic Biology ISBN: 978-1-904455-27-1 Price: £150
Edited by: Paul Blum
The authors present an expanding pattern of new information relevant to both the general and the technical reader. The book focuses on molecular biology and genomics and topics include the biology of metals, redox chemistry, respiration, sugar catabolism, nucleic acid modification, DNA replication, repair and recombination, signal transduction and transcriptomics. Throughout the well referenced text the emphasis is on emerging topics in specific fields providing the reader with a vision of the future in the expanding world of Archaea. Essential reading for all archaea researchers and everyone with an interest in prokaryote molecular and cellular biology. A recommended book for all microbiology libraries.
Available now ... ! Full information at Archaea: New Models for Prokaryotic Biology.
Legionella Molecular Microbiology ISBN: 978-1-904455-26-4 Price: £150
Edited by: Klaus Heuner and Michele Swanson
The main focus of the book is the current state of many of the most critical features of Legionella. Internationally renowned authors have contributed chapters describing and discussing the latest research findings with an emphasis on molecular aspects. The editors and authors have produced an excellent book that will be an extremely useful reference source. This comprehensive publication is aimed at readers with teaching or research interests in microbiology, genetics, genomics, infectious diseases or clinical research. A recommended book for all microbiology and clinical research laboratories.
Available now ... ! Full information at Legionella Molecular Microbiology.
RNA and the Regulation of Gene Expression: A Hidden Layer of Complexity ISBN: 978-1-904455-25-7 Price: £150
Edited by: Kevin V. Morris
The role of RNA in regulating gene expression has become a topic of intense interest. In this book internationally recognized experts in RNA research explore and discuss the methods whereby RNA can regulate gene expression with examples in yeast, Drosophila, mammals, and viral infection, and highlight the application of this knowledge in therapeutics and research. Topics include: gene silencing and gene activation, the hammerhead ribozyme, epigenetic regulation, RNAi, microRNA, and pyknons. This comprehensive publication is intended for readers with teaching or research interests in RNA, the regulation of gene expression, genetics, genomics or molecular biology.
Available now ... ! Full information at RNA and the Regulation of Gene Expression.
Molecular Oral Microbiology ISBN: 978-1-904455-24-0 Price: £150
Edited by: Anthony H. Rogers
The molecular biology of micro-organisms involved in the two major dental diseases: caries and periodontal disease. Chapters deal with the interactions of oral micro-organisms with one another and with the host; the innate defence mechanisms of the host; and the development of vaccines against oral diseases. Topics include oral microbial taxonomy, identification and typing, applied genomics, horizontal gene transfer, cell-cell communication, cariogenic bacteria, Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis, Treponema denticola, host-pathogen interaction, host defense mechanisms, and vaccination against oral infections. Essential reading for students and researchers in the field of oral biology and oral microbiology and a recommended book for all microbiology laboratories.
Available now ... ! Full information at Molecular Oral Microbiology.
Epigenetics ISBN: 978-1-904455-23-3 Price: £150
Edited by: Jörg Tost
In this book the molecular mechanisms and biological processes in which epigenetic modifications play a primordial role are described in detail. The first seven chapters describe the different biological mechanisms of the epigenetic machinery including: DNA methylation, histone tails, chromatin structure, nucleosome occupancy, Polycomb group proteins, siRNAs and miRNAs. The following chapters cover the epigenetic systems of plants, the epigenetic profile of embryonic stem cells, cell differentiation, imprinting marks, and random X chromosome inactivation. Further chapters deal with epigenetics in relation to cancers, premature aging, longevity and the developmental origins of disease. The final chapter, describes the fascinating potential transfer of epigenetic information across generations. This up-to-date volume is a major resource for those working in the field and will stimulate readers of all levels to dive into the fascinating and fast moving field of epigenetics.
Available now ... ! Full information at Epigenetics.
Animal Viruses: Molecular Biology ISBN: 978-1-904455-22-6 Price: £150
Edited by: Thomas C. Mettenleiter and Francisco Sobrino
In this book an international panel of leading virologists provide a state-of-the-art overview of the field, comprehensively detailing the current understanding of viruses, their replication, evolution and interaction with the host. The authors emphasize strategic and methodological aspects of current research, and provide key related references. Topics include foot-and-mouth disease virus, Pestivirus, Arteriviridae, Coronaviruses (including SARS), Herpesviridae, Paramyxoviridae, influenza viruses, Reoviridae, porcine circoviruses, Asfarviridae and much more. An essential text for all virology laboratories.
Available now ... ! Full information at Animal Viruses: Molecular Biology.
Segmented Double-Stranded RNA Viruses: Structure and Molecular Biology ISBN: 978-1-904455-21-9 Price: £150
Edited by: John T. Patton
This timely book brings together all of the key recent research on this disparate group of viruses, providing for the first time a single resource reviewing dsRNA viral structure and molecular biology.Written by well respected and experienced virologists, topics include: the structures of orthoreoviruses, rotavirus, phytoreoviruses, and bluetongue virus, entry into the bacterial cell, crystal structure of reovirus polymerase lambda3, assembly of the reovirus genome, genomic RNA packaging and replication in the Cystoviridae, and much more. Essential reading for all dsRNA virologists and all other virologists with an interest in molecular and sructural biology.
Available now ... ! Full information at Segmented Double-Stranded RNA Viruses.
Acinetobacter Molecular Biology ISBN: 978-1-904455-20-2 Price: £150
Edited by: Ulrike Gerischer
This concise volume reviews the most current and topical aspects of Acinetobacter genetics and molecular biology and is aimed at a readership of research scientists, graduate students and other specialists. Expert international authors have contributed chapters on diverse topics including taxonomy, lipopolysaccharides, catabolism of aromatic compounds, transformation systems, transcriptional regulation, applications in biotechnology, the molecular basis for virulence and pathogenicity, molecular epidemiology, and antibiotic resistance. This book is highly recommended for anyone involved in Acinetobacter research.
Available now ... ! Full information at Acinetobacter Molecular Biology.
Pseudomonas: Genomics and Molecular Biology ISBN: 978-1-904455-19-6 Price: £150
Editor: Pierre Cornelis
The genome sequences of several pseudomonads have become available in recent years and researchers are beginning to use the data to make new discoveries about this bacterium. This concise volume reviews the most current and topical aspects of Pseudomonas molecular biology and genomics and is aimed at a readership of research scientists, graduate students and other specialists. Renowned international authors have contributed chapters on diverse topics including taxonomy, genome diversity, oligonucleotide usage, polysaccharides, pathogenesis, virulence, biofilms, antibiotic resistance and iron uptake. In addition an entire chapter is devoted to the genetic tools being developed to take full advantage of the wealth of information generated by the genome sequencing efforts. This book is essential reading for anyone involved in Pseudomonas research.
Available now ... ! Full information at Pseudomonas: Genomics and Molecular Biology.
Real-Time PCR in Microbiology: From Diagnosis to Characterisation ISBN: 978-1-904455-18-9 Price: £150
Edited by: Ian M. Mackay
Real-time PCR has established itself as a sensitive and specific qualitative and quantitative technique that has become important to all areas of microbiology. This invaluable book describes and explains some of the more complex aspects of real-time PCR presenting a background for the novice, a theoretical reference for the experienced user, and useful discussions of future developments. Chapters address the basics of PCR history, oligonucleotide design, target preparation, standardisation, quantification, various applications, and future challenges. The final chapter is presented in the format of a roundtable discussion providing an insightful, topical and interesting discourse with contributions from over 30 authorities and experts on real-time PCR. The editor and authors have produced an excellent book that will be extremely useful for all microbiologists. A recommended book for all microbiology laboratories.
Available now ... ! Full information at Real-Time PCR in Microbiology: From Diagnosis to Characterisation.
Microbial Biodegradation: Genomics and Molecular Biology ISBN: 978-1-904455-17-2 Price: £150
Editor: Eduardo Díaz
In this timely book expert international authors critically review all of the most important topics in this exciting field. Although other books covering this are currently available, this book is unique in that it is the first to review the area from a molecular biology and genomics perspective. Topics covered include: aerobic and anaerobic biodegradation of aromatic compounds, molecular detection methods (e.g. microautoradiography, mRNA analyses, etc.), genome-based predictive modelling, elucidation of regulatory networks, bioavailability, chemotaxis and transport issues, functional genomic analyses, natural attenuation, community fingerprinting and metagenomics, biotreatment, and biocatalysts engineering. Essential reading for microbial degradation and bioremediation scientists and of general interest for microbiologists working in field of environmental microbiology.
Available now ... ! Full information at Microbial Biodegradation: Genomics and Molecular Biology.
Coronaviruses: Molecular and Cellular Biology ISBN: 978-1-904455-16-5 Price: £150
Editor: Volker Thiel
In this timely book, internationally renowned experts review literally every aspect of cutting edge coronavirus research providing the first coherent picture of the molecular and cellular biology since the outbreak of SARS in 2003. The book is divided into two sections: Part I focuses on the molecular biology of the virus itself and includes topics such as coronavirus binding and entry, replicase gene function, cis-acting RNA elements, coronavirus discontinuous transcription, reverse genetics, genome packaging and molecular evolution. In Part II of the book, the focus is on molecular and cellular pathogenesis and infection control. This section includes reviews of the three prototype viruses, namely avian infectious bronchitis virus, feline coronavirus and mouse hepatitis virus. Other topics include SARS-CoV virus pathogenesis, SARS-CoV interaction with the host INF and antiviral cytokines, the newly recognized bat coronaviruses and human coronavirus NL63, and strategies for coronavirus vaccine development and the development of novel antiviral coronavirus agents.
Available now ... ! Full information at Coronaviruses: Molecular and Cellular Biology.
The Cyanobacteria: Molecular Biology, Genomics and Evolution ISBN: 978-1-904455-15-8 Price: £150
Editors: Antonia Herrero and Enrique Flore
This volume brings together the expertise and enthusiasm of an international panel of leading cyanobacterial researchers to provide a state-of-the art overview of the field. Topics covered include: evolution, comparative genomics, gene transfer, molecular ecology and environmental genomics, stress responses, bioactive compounds, circadian clock, structure of the photosynthetic apparatus, membrane systems, carbon acquisition, nitrogen assimilation and C/N balance sensing and much more. Essential for anyone with an interest in cyanobacteria, bacterial photosynthesis, bacterial nitrogen fixation, and symbosis.
Available now ... ! Full information at The Cyanobacteria: Molecular Biology, Genomics and Evolution.
Bacteriophage: Genetics and Molecular Biology ISBN: 978-1-904455-14-1 Price: £150
Edited by: Stephen McGrath and Douwe van Sinderen
Written by eminent international researchers actively involved in the disparate areas of bacteriophage research this book focuses on the current rapid developments in this exciting field. The book opens with an excellent chapter that provides a broad overview of the topics and also highlights the multifaceted nature of bacteriophage research. This is followed by a series of reviews that focus on the current most cutting-edge topics including bioinformatics and genomics, phage in the environment, bacteriophage in medicine, transfer of phage DNA to the host, contribution to host phenotype and much more.
Available now ... ! Full information at Bacteriophage: Genetics and Molecular Biology.
Candida: Comparative and Functional Genomics ISBN: 978-1-904455-13-4 Price: £150
Edited by: Christophe d'Enfert and Bernhard Hube
In this timely book international experts provide comprehensive and authoritative reviews of these important organisms. Topics covered include: genome dynamics of C. albicans; molecular epidemiological and population studies of C. albicans; the parasexual cycle in C. albicans; comparative genomics of the hemiascomycetes group and of different Candida species; databases and the challenges that their curators are facing; transcriptome analysis; proteomics; molecular evolution of the genetic code; stress responses; regulation of morphogenesis; cell wall biology; interaction with host cells; analysis of gene function; antifungal resistance mechanisms and much more.
Available now ... ! Full information at Candida: Comparative and Functional Genomics.
Bacillus: Cellular and Molecular Biology ISBN: 978-1-904455-12-7 Price: £150
Edited by: Peter Graumann
This book presents an overview of the most recent exciting new research fields and provides a picture of the major cytological aspects of a model bacterium. The authors present the most recent knowledge on topics such as the replication and segregation of the chromosome, cell division, replication and growth, the cell cycle, transcription, translation, regulation, the actin cyctoskeleton, the cell membrane and cell wall, biofilm formation and sporulation. Also covered are DNA repair, the regulation of transcription through RNA molecules, and the regulation of protein activity through proteolysis. The authors seamlessly merge the fields of bacterial cell biology and molecular biology to provide an integral view of the bacterial cell, providing an understanding of the way a bacterial cell functions as a whole entity and in 3D, i.e. how it is spatially organized, and even how bacterial cells communicate with each other, or give their life for the sake of the whole community.
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AIDS Vaccine Development: Challenges and Opportunities> ISBN: 978-1-904455-11-0 Price: £49
Edited by: Wayne Koff, Patricia Kahn and Ian D. Gust
This book reviews the scientific challenges that have impeded the search for an effective AIDS vaccine and discusses current novel research that is accelerating progress. In a series of mini-reviews by the world's leading experts in AIDS vaccine research the book is essential reading for everyone interested in the current progress and future direction of AIDS vaccine development.
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Pathogenic Treponema: Molecular and Cellular Biology ISBN: 978-1-904455-10-3 Price: £140
Edited by: Justin D. Radolf and Sheila A. Lukehart
In recent years there has been an explosion of new information that is summarised in the current volume. Expert international authors critically review every aspect of the molecular and cellular biology of these fascinating organisms. The focus of the book is on recent advances and new developments in Treponema research, in particular those resulting from modern molecular and genetic methodologies. Topics covered include the phylogenic diversity, comparative genomics, metabolism and cultivation, motility, antigenic variation, immunology of syphilis, the use cultivatable treponemes as surrogates for T. pallidum, oral treponemes, and much much more. Essential reading for all scientists and researchers working on trepenomes and other spirochetes and a recommended reference book for all microbiology laboratories.
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Alpha Herpesviruses: Molecular and Cellular Biology ISBN: 978-1-904455-09-7 Price: £140
Edited by: R. M. Sandri-Goldin
Written by internationally recognized experts, this book highlights the more provocative and exciting findings in herpesvirus research. Each chapter is a review of a specific area with an emphasis on recent advances and the latest developments. Topics include: multifunctional proteins, advances in DNA replication, new information on the regulation of gene expression, the emergence of new technologies, recent technological advances in fluorescent probes, the induction of apoptosis, the disruption of interferon, vaccine development and drug design. With a specific focus on new and topical herpesvirus research, this book is essential reading for everyone with an interest in herpesviruses and recommended reading for other scientists working in viral pathogenesis, viral genomics and antiviral research.
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PCR Troubleshooting: The Essential Guide ISBN: 78-1-904455-07-3 Price: £30
Author: Michael L. Altshuler
This book is an essential companion for anyone who uses the polymerase chain reaction technique. The author presents a PCR troubleshooting guide accompanied by a consideration of ways to obviate rather than overcome PCR problems. If you ever fail at PCR, consult this book! Oriented to a reader with some experience in PCR the concise guide will be invaluable to both expert and novice users alike.
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Influenza Virology: Current Topics ISBN: 978-1-904455-06-6 Price: £130
Edited by: Yoshihiro Kawaoka of the School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI 53706, USA
In this timely book world renown scientists (including the 1996 Nobel Prize Winner, Peter Doherty) critically review the most important issues in this rapidly expanding field. Topics covered include analysis of influenza RNP, viral entry and intracellular transport, epidemiology, host range and pathogenicity, antivirals, vaccines, H5 viruses, and much more. Essential reading for all influenza virologists, molecular biologists, public health scientists and research scientists in pharmaceutical companies.
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Microbial Subversion of Immunity: Current Topics ISBN: 978-1-904455-05-9 Price: £115
Edited by: Peter J. Lachmann of the Centre for Veterinary Science, Madingley Road, Cambridge CB3 0ES M.B.A. Oldstone of the The Scripps Research Institute, La Jolla, CA 92037, USA
In this book internationally renown scientists critically review the current cutting-edge research in this area. Topics covered include the subversion of complement, NK cell function, mucosal innate immune response, evasion/subversion mechanisms used by bacteria, helminths, viruses, and the measles model system. Containing over 1,700 references, this book is an essential resource book for researchers in the fields of microbiology, immunology, pharmacology and molecular medicine.
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Papillomavirus Research: From Natural History To Vaccines and Beyond ISBN: 978-1-904455-04-2 Price: £150
Edited by: M. Saveria Campo, Institute of Comparative Medicine, University of Glasgow, UK
In this timely book leading scientists review current aspects of papillomavirus research providing a fascinating insight into papillomavirus molecular biology, interactions with the host, immunology and vaccine development. Topics covered include epidemiology and taxonomy, phylogenetic analyses, gene expression, regulation of DNA replication, transcription factor proteins, organotypic raft cultures, virus-like particles, and much more. Essential reading for scientists and researchers working on papillomavirus and a recommended text for anyone involved with antiviral drug and vaccine development.
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Epstein Barr Virus ISBN: 978-1-904455-03-5 Price: £150
Edited by: Erle S. Robertson, University of Pennsylvania Medical School, USA
World renowned EBV experts provide a critical and comprehensive review of every aspect of this important virus. By integrating genetic, immunologic, and cell biologic approaches to elucidate pathogenesis, penetrating new insights into the molecular and cellular interaction between EBV and its human host have emerged. Topics covered include: Discovery, history and seroepidemiology, EBV and the immune response, EBV genetics, EBV infection and persistence, latency, lytic proteins and reactivation control, vaccine approaches, animal models, and the future of EBV studies. This is essential reading for all EBV virologists as well as clinical and research scientists working on oncogenic viruses.
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Cytomegaloviruses: Molecular Biology and Immunology ISBN: 978-1-904455-02-8 Price: £140
Edited by: Matthias J. Reddehase, Johannes Gutenberg University, Mainz, Germany
The focus of the book is on the molecular and genomic aspects and the authors provide an insight into the current understanding of the subject and the future direction of research. Topics covered include disease mechanisms, genomics, proteomics, BAC mutagenesis, virus entry and activation of innate immunity, regulation of viral gene expression, regulation of viral mRNA export, animal models of infection, novel therapeutics, vaccine development, antivirals, and much more. Essential reading for all virologists with an interest in cytomegaloviruses and a recommended text for scientists working on antiviral drug and vaccine development.
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Foodborne Pathogens: Microbiology and Molecular Biology ISBN: 978-1-904455-00-4 Price: £149
Edited by: Pina M. Fratamico, Arun K. Bhunia and James L. Smith, USDA, Wyndmoor, USA and Purdue University, West Lafayette, USA
Written by leaders in the field, this book represents a cutting edge summary of all the latest advances, providing the first coherent picture of the current status. Opening chapters tackle topics such as pathogen detection (molecular, biosensor), molecular typing, viable but non-culturable organisms, predictive modeling, and stress responses. The next section covers groups of organisms: enteric viruses, protozoan parasites, and mycotoxins. This is followed by chapters on specific bacteria: Yersinia enterocolitica, Vibrio spp., Staphylococcus aureus, Campylobacter spp., Listeria monocytogenes, Salmonella spp., Shigella spp., Escherichia coli, Clostridium botulinum, Clostridium perfringens and Bacillus cereus. The final chapters provide a fascinating review of the ability of pathogens to contaminate a food supply and provide an overview of emerging foodborne pathogens.
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HIV Chemotherapy: A Critical Review ISBN: 978-0-9542464-9-5 Price: £110
Edited by: Salvatore T. Butera, Centers for Disease Control and Prevention, Atlanta, USA
Expert AIDS researchers critically review every aspect of this highly topical subject. The opening chapters deal with the management of HIV infections and include a fascinating review of current molecular strategies to protect and strengthen the host immune system at the cellular level. Further chapters summarise the strategies required for the implementation of effective anti-HIV therapies in developing countries and comprehensively review the genetics of viral drug resistance, and current drug-resistance testing technologies. The remaining chapters provide cutting-edge reviews of the latest viral and cellular targets for anti-HIV chemotherapy, the development of iRNA based therapeutics and molecular based strategies that target latent virus reservoirs in infected individuals. Essential reading for scientists and clinicians working on AIDS, HIV, and other retroviruses as well as all health care professionals interested in expanding their current understanding of the subject.
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Pathogenic Fungi: Host Interactions and Emerging Strategies for Control ISBN: 978-0-9542464-8-8 Price: £99
Edited by: Gioconda San-Blas and Richard A. Calderone, Caracas, Venezuela and Washington DC, USA
The book is divided into two sections: "Fungal Interactions with the Host" and "Antifungal Antibiotics". The emphasis of the first section is focused on the two-way recognition systems that exist between the host and the fungus. Experts in fungal-host interactions discuss new initiatives for alternatives to drug therapy through the development of vaccines and passive antibody therapy. In the "Antifungal Antibiotics" section, new target development, molecular modelling, and drug resistance, both at the individual organism level, and in a biofilm, are featured. Essential reading for everyone with an interest in medical mycology including: mycologists, biotechnologists, molecular biologists, and pharmaceutical and biotechnology companies.
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Pathogenic Fungi: Structural Biology and Taxonomy ISBN: 978-0-9542464-7-1 Price: £99
Edited by: Gioconda San-Blas and Richard A. Calderone, Caracas, Venezuela and Washington DC, USA
The book is divided into two sections: "Fungal Dimorphism and Pathogenicity" and "New Taxonomic Tools". The first section focuses on morphogenesis, the cell cycle, and the cell wall of human pathogens. These play a major role in elucidating fungal relationships, both with the environment and with the host. Experts in fungal structural biology contribute in-depth reviews on a variety of topics with a focus on molecular and biochemical analysis. The final chapter in this section presents a fascinating review of how mathematical modelling can be used to understand the building of three-dimensional cell structures in the morphogenetic process. The second section, entitled "New Taxonomic Tools", presents novel approaches to aid the understanding of strain variability, the significance of environmental and patient strains, and the relatedness of "uncultured" fungi. In addition the use of molecular tools for the taxonomic classification of previously unclassifiable fungi is featured. Essential reading for everyone with an interest in medical mycology including: mycologists, biotechnologists, molecular biologists, and pharmaceutical and biotechnology companies.
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Malaria Parasites: Genomes and Molecular Biology ISBN: 978-0-9542464-6-4 Price: £115
Edited by: Andrew P. Water and Chris J. Janse, Leiden University Medical Centre, Leiden, The Netherlands
In this book internationally renown experts provide up-to-date reviews of the most important aspects of post-genomic malaria research. Topics covered include: the P. falciparum genome and model parasites, bioinformatics and genome databases, microsatellite analysis, analysis of chromosome structure, cell cycle to RNA polymerase I and II mediated gene expression, role of the nuclear genome, the parasite surface and cell biology, and much more. The book is essential reading for all parasitologists and scientists with an interest in malaria.
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MRSA: Current Perspectives ISBN: 978-0-9542464-5-7 Price: £90
Edited by: Ad C. Fluit and Franz-Josef Schmitz, Utrecht, The Netherlands
In this book, internationally renown authors comprehensively review all aspects of MRSA research. Topics covered include strategies for the detection and typing of MRSA strains, epidemiological characterisation, molecular evolution of MRSA, vancomycin resistant S. aureus, mechanisms of methicillin resistance, virulence mechanisms in MRSA pathogenesis, recommended treatment of MRSA infections and options for the prevention and control of MRSA infections. An essential text for all scientists and clinicians with an interest in Staphylococcus aureus or antibiotic resistance.
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Frontiers in Computational Genomics ISBN: 978-0-9542464-4-0 Price: £90
Edited by: Michael Y. Galperin and Eugene V. Koonin, National Center for Biotechnology Information, Bethesda
Computational biology and bioinformatics form a major, integral part of genomics. From sequence fragment assembly, to gene prediction, to prediction of protein functions and structure, to identification of regulatory signals in DNA, to building phylogenetic trees, it would not be an exaggeration to state that genomics is primarily computational. Major new programs, software and internet facilities have evolved recently that facilitate computational analysis and more novel technologies are currently being developed. Written by experts in the field, this volume highlights research on the emerging, perhaps somewhat controversial, topics in genomics and shows the feedback between the new developments and the established methods of computational biology. An essential book for anyone involved in genomic science or bioinformatics.
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Genomics of GC Rich Gram-Positive Bacteria ISBN: 978-0-9542464-3-3 Price: £75
Edited by: Antoine Danchin, HKU-Pasteur Research Centre, Hong Kong
Eminent scientists have contributed comprehensive reviews on all aspects of the genomics of Rhodococcus, Mycobacteria, Streptomyces and other organisms. The authors provide an insight into the many facets of large-scale functional investigation in a variety of bacteria with the explicit goal to find common rules in the dynamic and structural organisation of these organisms. This volume is the definitive guide to current research in this increasingly important area.
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Genomic Technologies: Present and Future ISBN: 978-0-9542464-2-6 Price: £90
Edited by: David Galas and Stephen McCormack, Keck Graduate Institute, Claremont and AlleCure, Valencia, California
The chapters in this book reflect the range of technical advances and their applications that are currently transforming biology. Topics covered include the application of computational methods, the robotics of modern automation methodologies, the new chemical and imaging methods that reveal chromosome structure and elucidate gene function, and the emergence of evolutionary and functional information by comparative genomics. Eminent international scientists describe in detail the new technology necessary to study the entire genome in a holistic manner and all the high throughput and large-scale experimental methodologies currently being used in genomic science. In addition the authors describe the progress of the newest technologies that are currently being developed. Written by experts in the field, this concise yet informative volume covers all aspects of technology pertaining to genomic studies. An essential book for anyone involved in genomic science. An essential book for anyone involved in genomic science.
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Probiotics and Prebiotics: Where are We Going? ISBN: 978-0-9542464-1-9 Price: £90
Edited by: Gerald W. Tannock, University of Otago, Dunedin, New Zealand
State-of-the-art commentaries on all aspects of the intestinal microflora and probiotics and provides an authoritative review of important aspects of probiotic and prebiotic research. Written by leading experts in the field, each chapter affords a critical insight to a particular topic, reviews current research, discusses future direction and aims to stimulate discussion. Topics covered include the genomics of probiotic microorganisms, the developing technologies for analysis of gut microorganisms, evaluation and future potential of prebiotic substances, and the potential for disease prevention in the host by probiotic organisms. An essential text for all microbiologists, health professionals, biotechnologists, pharmaceutial companies, dairy and food scientists.
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