Microbiology news and views
J. Mol. Micro. Biotechnol. 3: 457-459
Prokaryotic Calmodulins: Recent Developments and Evolutionary Implications
Keqian Yang
Ca2+ is a common intracellular second-messenger molecule in eukaryotic cells and regulates a myriad of cellular processes. Many effects of Ca2+ are mediated by calcium-binding regulatory proteins of the calmodulin superfamily. We propose the idea that calcium-binding proteins originated in high G+C Gram-positive bacteria and were later acquired by eukaryotes.
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