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J. Mol. Micro. Biotechnol. 4: 269-276
The Molecular Biology of Formate Metabolism in Enterobacteria
Susanne Leonhartsberger, Ingrid Korsa, and August Böck
Formate is the signature compound in the anaerobic metabolism of Escherichia coli and other enterobacteria. Its synthesis and degradation is integrated in a net-work of metabolic routes which are elegantly regulated to adjust the carbon flux to the metabolic needs. This review summarises the information on the biochemistry of synthesis and degradation of formate, on the genetics of the members of the regulon and on the mechanism underlying the regulation.
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