Medical Microbiology Books
 | Edited by: Seng-Lai Tan and Yupeng He Published: 2011 ISBN: 978-1-904455-78-3 Price: GB £180 or US $350 In-depth reviews of the most critical areas of HCV research. Includes the HCV life cycle, HCV assays, HCV resources, HCV databases, HCV infection systems, models of hepatitis C infections, overview of the drug pipeline, clinical trial design, clinical virology and drug development, NS3 protease inhibitors, NS3-NS4A complex inhibitors, NS3 helicase inhibitors, NS4B targets and inhibitors, NS5A inhibitors, nucleoside inhibitors, NS5B polymerase inhibitors, glycoprotein-dependent entry, host cell targets and inhibitors, and innate immunity for HCV antiviral therapy. read more ... |
 | Edited by: Sandra K. Weller Published: 2011 ISBN: 978-1-904455-76-9 Price: GB £180 or US $350 This up-to-date and comprehensive volume aims to distill the most important research on alphaherpesvirus molecular virology providing a timely overview of the field. Topics covered include: transcriptional regulation, DNA replication, translational control, virus entry and capsid assembly, the role of microRNAs in infection and oncolytic vectors for cancer therapy. In addition there is coverage of virus-host interactions, including apoptosis, subversion of host protein quality control and DNA damage response pathways, autophagy, establishment and reactivation from latency, interferon responses, immunity and vaccine development. Essential reading for everyone working with alphaherpesviruses and of interest to all virologists working on latent infections. read more ... |
 | Edited by: Rino Rappuoli and Fabio Bagnoli Published: 2011 ISBN: 978-1-904455-74-5 Price: GB £180 or US $350 The book has been divided into two parts. The first part reviews the technologies and approaches used to identify, generate and test new vaccines. Topics include: new strategies to identify protective antigens, generation of improved adjuvants, use of alternative immunization routes, improving vaccine safety, and finding and establishing the correlates of protection. The second part of the book focuses on the development of new vaccines to replace or complement currently available products or for diseases against which prophylactic strategies are missing. Examples include vaccines against nosocomial infections, streptococci, emerging viral diseases, P. aeruginosa, and bovine mastitis. Essential reading for everyone with an interest in vaccine research. read more ... |
 | Edited by: Steffen Porwollik Published: 2011 ISBN: 978-1-904455-73-8 Price: GB £159 or US $310 In this book, internationally acclaimed experts review cutting-edge topics in Salmonella genomics and molecular biology. Topics include latest approaches to sub-species level classification and phage typing of Salmonella, comparative genomics, the search for genetic determinants for survival of the bacterium in different environments and the evolution of niche specialization by Salmonella. The book also explores the latest genomic information and molecular characterizations of sRNAs and complements of fimbriae, flagella and secreted virulence factors. Moreover, S. Typhi pathogenesis, interactions of the host with intracellular Salmonella and the host's anti-Salmonella immune response are reviewed. The current knowledge on Salmonella biofilm formation and a progress report on using Salmonella as an anti-tumour tool conclude this compendium. read more ... |
 | Edited by: Sassan Asgari and Karyn N. Johnson Published: 2010 ISBN: 978-1-904455-71-4 Price: GB £180 or US $350 Written by internationally renowned insect virologists, chapters cover all of the major groups of insect pathogenic viruses and suggest future directions for research. The book is divided into three parts: 1) DNA viruses 2) RNA viruses and 3) current hot-topics in insect virology. Virus groups covered include: Ascoviruses, Baculoviruses, Densoviruses, Entomopoxviruses, Hytrosaviruses, Iridoviruses, Nudiviruses, Polydnaviruses, Dicistroviruses, Iflaviruses, Nodaviruses, Tetraviruses and Cypoviruses. The special topics chapters review exciting recent developments in insect virology including RNAi, insect antiviral responses, structural comparison of insect RNA viruses, and viral ecology. The book is essential reading for every insect virologist in both the academic and private sectors. It is also strongly recommended for other virologists, particularly those interested in virus evolution, virus structure, viral vectors, biological control of insects and insect immunity. read more ... |
 | Edited by: Baltasar Mayo and Douwe van Sinderen Published: 2010 ISBN: 978-1-904455-68-4 Price: GB £159 or US $310 This book brings together the expertise and enthusiasm of the leading bifidobacteria experts from around the world to provide a state-of-the art overview of the molecular biology and genomics of this exciting and important microbial genus. Topics include: ecology, genomics, comparative genomics, metabolism, acid and bile resistance, stress response, probiotic properties, antimicrobial activity, interaction with the intestinal mucosa, safety assessment of bifidobacteria, synthesis and utilization of exopolysaccharides and prebiotics, antibiotic resistance/susceptibility profiles, viability and stability in commercial preparations, mobile genetic elements, cloning vectors and genetic manipulation of bifidobacteria. Essential reading for every bifidobacteria researcher, from the PhD student to the experienced scientist, and recommended reading for everyone with an interest in probiotics. read more ... |
 | Edited by: Grant S. Hansman, Xi Jason Jiang and Kim Y. Green Published: 2010 ISBN: 978-1-904455-63-9 Price: GB £159 or US $310 In this book, a panel of expert calicivirologists have selected the most important up-to-date research findings to produce timely and comprehensive reviews of the respective calicivirus field. Each chapter gives the reader a brief introduction to the topic followed by a descriptive discussion of the past and present research areas. Topics include: norovirus epidemiology; calicivirus contamination of the environment; genome organization and recombination, proteolytic cleavage and viral proteins; viral protein structures; virus-host interactions; calicivirus reverse genetics and replicon systems; feline calicivirus; swine calicivirus; murine norovirus pathogenesis and immunity; murine norovirus translation, replication and reverse genetics; and lagoviruses. read more ... |
 | Edited by: Erle S. Robertson Published: 2010 ISBN: 978-1-904455-62-2 Price: GB £159 or US $310 Expert EBV virologists comprehensively review this important subject from a genetic, biochemical, immunological, and cell biological perspective. Topics include: latent infections, EBV leader protein, EBNA-1 in viral DNA replication and persistence, EBNA-2 in transcription activation of viral and cellular genes, the nuclear antigen family 3 in regulation of cellular processes, molecular profiles of EBV latently infected cells, latent membrane protein 1 oncoprotein, regulation of latency by LMP2A, role of noncoding RNAs in EBV-induced cell growth and transformation and the regulation of EBV latency by viral lytic proteins. This book is essential reading for all EBV virologists as well as clinical and basic scientists working on oncogenic viruses. read more ... |
 | Edited by: C. Graham Clark, Patricia J. Johnson and Rodney D. Adam Published: 2010 ISBN: 978-1-904455-61-5 Price: GB £159 or US $310 In this book internationally acclaimed researchers critically review the most important aspects of research on anaerobic parasitic protozoa, providing the first coherent picture of their genomics and molecular biology since the publication of the genomes. Chapters are written from a molecular and genomic perspective and contain speculative models upon which future research efforts can be based. read more ... |
 | Edited by: Moira Desport Published: 2010 ISBN: 978-1-904455-60-8 Price: GB £159 or US $310 In this timely book, top lentivirus and macrophage specialists comprehensively review cutting-edge topics in the molecular and cellular biology of the lentivirus-macrophage interaction. Topics include lentivirus tropism and disease, macrophage biology, macrophage in HIV-1 infection and disease progression, post-entry restrictions to lentiviral replication, HIV-2 tropism and disease, SHIV model of disease, the felid immunodeficiency viruses, EIAV, small ruminant lentiviruses, bovine lentiviruses, coinfections and superinfections. read more ... |
 | Edited by: D. Scott Samuels and Justin D. Radolf Published: 2010 ISBN: 978-1-904455-58-5 Price: GB £159 or US $310 A comprehensive guide to Borrelia providing an encyclopedic overview of the molecular biology of this important genus and the pathogenesis of diseases Borellia causes. Leading authorities have contributed chapters on topics such as Borrelia genomics, DNA replication, gene regulation, transcriptomics, proteomics, metabolism and physiology, cellular structure, motility and chemotaxis, genetic manipulation, evolutionary genetics, ecology, tick interactions, Lyme disease and relapsing fever pathogenesis, animal models, host response, detection, and vaccines read more ... |
 | Edited by: Qinghua Wang and Yizhi Jane Tao Published: 2010 ISBN: 978-1-904455-57-8 Price: GB £159 or US $310 H1N1 influenza subtype causes a relatively mild infection in humans, however it is highly transmittable between people and a new influenza pandemic has been declared. If this virus were to acquire some of the lethal capabilities of H5N1, then the ensuing pandemic could be devastating. This book critically reviews the current research and the most important discoveries in this highly topical field. Subjects covered include the NS1 protein of influenza A virus, the structure of influenza NS1, influenza B hemagglutinin, influenza A nucleoprotein, influenza A hemagglutinin glycoproteins, the M2 channel, virulence genes of the 1918 pandemic influenza, influenza virus polymerase, gene diagnostic microarrays, and computer-assisted vaccine design. read more ... |
 | Edited by: Miguel Angel Martínez Published: 2010 ISBN: 978-1-904455-56-1 Price: GB £159 or US $310 In this book, expert RNAi specialists from around the world have teamed up to produce a timely and thought-provoking review of the area. The two central themes are the latest findings on RNAi-virus interactions and the current progress in the development of RNAi-based antiviral therapeutics. A number of chapters explain general concepts concerned with the role of RNAi in natural antiviral defense mechanisms, other chapters discuss how to improve the efficacy and safety of RNAi-based antiviral drugs, while others describe how this technology is being developed as a new therapeutic tool for fighting specific viruses, including HIV, HCV and respiratory viruses. Authors also outline potential new avenues for research thus providing a stimulus for further research. read more ... |
 | Edited by: Reinhard Kurth and Norbert Bannert Published: 2010 ISBN: 978-1-904455-55-4 Price: GB £159 or US $310 Written by the top retroviral specialists, this book reviews the genomics, molecular biology, and pathogenesis of these important viruses, comprehensively covering all the recent advances. Topics include: host and retroelement interactions, endogenous retroviruses, retroviral proteins and genomes, viral entry and uncoating, reverse transcription and integration, transcription, splicing and RNA transport, pathogenesis of oncoviral infections, pathogenesis of immunodeficiency virus infections, retroviral restriction factors molecular vaccines and correlates of protection, gammaretroviral and lentiviral vectors, non-primate mammalian and fish retroviruses, simian exogenous retroviruses, and HTLV and HIV. read more ... |
 | Edited by: Diana Marco Published: 2010 ISBN: 978-1-904455-54-7 Price: GB £159 or US $310 The diverse and multiple aspects of metagenomics and the multiplicity of its potential applications. The new theoretical insights, the more recent applications, and the dynamically developing methods of data acquisition and analysis. Essential reading for all researchers wishing to broaden their knowledge of metagenomics and highly recommended for those new to the field. read more ... |
 | Edited by: Masayuki Machida and Katsuya Gomi Published: 2010 ISBN: 978-1-904455-53-0 Price: GB £159 or US $310 In this book leading Aspergillus researchers review and summarise the most important aspects of Aspergillus molecular biology and genomics. The book opens with a fascinating overview of the genus Aspergillus. This is followed by in-depth reviews of the Aspergillus molecular systematics, comparative genomics, bioinformatics and systems biology of Aspergillus, transcriptional regulation, genetics and genomics of sexual development of A. nidulans, genomics and secondary metabolism, ecology, development and gene regulation in A. flavus, functional systems biology, and novel industrial applications of A. oryzae genomics. Essential reading for everyone with an interest in Aspergillus and related fungi. read more ... |
 | Edited by: Caroline Genco and Lee Wetzler Published: 2010 ISBN: 978-1-904455-51-6 Price: GB £150 or US $310 The latest theory and clinical significance of molecular mechanisms in meningococcal disease. Leading authorities have contributed chapters on topics such as gene expression, genomics, biofilms, denitrification, adhesion strategies, mechanisms of cellular invasion, inate immunity, complement, apoptosis, acquired immunity, vaccine development, epidemiology and antibiotic resistance. read more ... |
 | Edited by: Kathryn A. Hanley and Scott C. Weaver Published: 2010 ISBN: 978-1-904455-50-9 Price: GB £150 or US $310 Topics include: evolutionary history, epidemiology, translation and processing of the viral polyprotein, viral replication, the role of the viral untranslated regions, pathogenesis, host response to DENV, development of animal models, DENV-mosquito interactions, dynamics of dengue virus transmission, emergence of DENV from its ancestral, sylvatic cycle, vaccines, novel anti-dengue drugs, and passive immunotherapy. Essential reading for every dengue virologist and highly recommended for all flavivirus and arbovirus virologists. read more ... |
 | ABC Transporters in Microorganisms: Research, Innovation and Value as Targets against Drug Resistance Buy now! Edited by: Alicia Ponte-Sucre Published: 2009 ISBN: 978-1-904455-49-3 Price: GB £150 or US $310 The topics include the structure, physiology and evolution of ABC transporters, and their special characteristics in bacteria, yeast, trypanosomes and malaria parasites. The book covers the most recent research into the role of ABC transporters in the design of strategies to circumvent drug resistance. Each chapter comprises an exhaustive review of the particular topic from both the scientific and clinical perspective. read more ... |
 | Edited by: Ken Jarrell Published: 2009 ISBN: 978-1-904455-48-6 Price: GB £150 or US $310 The current knowledge and latest research on prokaryotic pili and flagella. The emphasis is on the molecular biology, genetics, structure, assembly and function of these structures. read more ... |
 | Edited by: Keith E. Herold and Avraham Rasooly Published: 2009 ISBN: 978-1-904455-47-9 Price: GB £150 or US $310 Applications of lab-on-a-chip devices in biotechnology, medicine, clinical diagnostics, chemical engineering, and pharmaceutics. Various electrophoresis and liquid chromatography applications, methods for cell separation, blood cell separation, clinical applications, protein, genetic, PCR, transcriptome analysis, cell manipulation and analysis, cell viability analysis, microorganism capturing. read more ... |
 | Edited by: Keith E. Herold and Avraham Rasooly Published: 2009 ISBN: 978-1-904455-46-2 Price: GB £150 or US $310 Current lab-on-a-chip technologies including theoretical and technical information for the understanding of the technology and the reproduction of experiments. Will help the understanding of current LOC technologies, performance of similar experiments, the design of new LOC systems and development of new methodologies and applications. read more ... |
 | Edited by: Matthias Ullrich Published: 2009 ISBN: 978-1-904455-45-5 Price: GB £150 or US $310 In this timely book a cohort of experienced and authoritative experts review the most important innovations in research on and biotechnological applications of bacterial polysaccharides. The book takes an interdisciplinary view that examines this fascinating subject area in detail from molecular biology, genome-, transcriptome- and proteome-wide perspectives, and looks at the ecological aspects and systems biology approaches. Hence the book provides a sound basis for future research directions including high efficiency applications of bacterial polysaccharides in medicine, the food industry, and renewable energy production. read more ... |
 | Edited by: Thomas Proft Published: 2009 ISBN: 978-1-904455-44-8 Price: GB £150 or US $310 This timely volume serves as an update on the most important microbial toxins. Written by internationally respected scientists, topics reviewed include: toxins carried by mobile genetic elements, botulinum neurotoxins, anthrax, subtilase cytotoxin, Pasteurella multocida toxin, RTX toxins of vibrios, vacA toxin, staphylococcal immune evasion toxins and fungal ribotoxins. read more ... |
 | Author: Naveed Khan Published: 2009 ISBN: 978-1-904455-43-1 Price: GB £150 or US $310 Everything that is known about Acanthamoeba is critically reviewed and divided into easy-to-follow sections. The current state of research on genomics, molecular and cellular biology, life cycles, geographical distribution, role in ecosystem, morphology, motility, phylogenetics, genotyping, metabolism, regulation of morphogenesis, host-parasite interactions, the molecular and immunological basis of pathogenesis, methods of transmission, epidemiology, clinical manifestation, diagnosis, treatment, new target development and drug resistance, and much more. read more ... |
 | Edited by: Karl Wooldridge Published: 2009 ISBN: 978-1-904455-42-4 Price: GB £150 or US $310 A broad and in-depth description of the current knowledge of bacterial protein secretion and its role in pathogenesis. This publication on bacterial secreted proteins, the secretory systems of bacteria and the vital role of secreted proteins in bacterial pathogenesis is aimed at microbiologists, molecular biologists, public health scientists and researchers engaged in the study of pathogenesis, drug design and vaccine development. read more ... |
 | Edited by: Åsa Ljungh and Torkel Wadström Published: 2009 ISBN: 978-1-904455-41-7 Price: GB £150 or US $310 A major new reference for all medical researchers, dairy technologists, microbiologists and biotechnologists in the academic and industrial sectors. Written by an international team of scientists the volume focuses on recent research on the molecular biology and genomics of Lactobacillus. Topics covered include phylogenetics, taxonomy, comparative genomics, functional genomics, the intestinal microflora, surface proteins, stress responses, interaction with the immune system, probiotics, anti-cancer potential, and much more. Essential reading for all scientists involved with lactic acid bacteria or probiotic research and a recommended book for all microbiology laboratories. read more ... |
 | Edited by: Tanya Parish and Amanda Brown Published: 2009 ISBN: 978-1-904455-40-0 Price: GB £150 or US $310 A critical review of the current and most recent advances in the genomics and molecular biology of mycobacteria. Focuses on the topical and most relevant aspects. Includes strain variation and evolution, hypervirulent strains, electron transport and respiration, lipid biosynthesis, DNA repair, oxygen signaling, sulphur metabolism, protein secretion, the protein kinase family. read more ... |
 | Edited by: Holger Brüggemann and Gerhard Gottschalk Published: 2009 ISBN: 978-1-904455-38-7 Price: GB £150 or US $310 In this book internationally recognised Clostridium experts critically review the most important aspects of clostridial research, providing the first coherent picture of the organism's molecular and cellular biology in this post-genomic era. The first major focus of the book is the genetics and molecular biology of the major clostridial toxins including: botulinum and tetanus neurotoxins, C. difficile large exotoxins, C. perfringens enterotoxin, pore-forming and binary bacterial toxins. Other topics include: molecular epidemiology of C. botulinum and C. difficile, metabolic networks in C. acetobutylicum, development of genetic knock-out systems for clostridia, surface structures, anti tumor potential of clostridia, and antibiotic resistance determinants in C. difficile. read more ... |
 | Edited by: Georg Lipps Published: 2008 ISBN: 978-1-904455-35-6 Price: GB £150 or US $310 Written by acknowledged experts in the field, this volume provides an up to date treatment of the structure, function and application of plasmids with a particular emphasis on current and future trends. The book is aimed primarily at research scientists, graduate students and professional scientists but will also be of great interest to all molecular biologists and microbiologists involved in research or teaching. Chapters include a historical perspective on E. coli plasmids and the scientific background of the plasmids used routinely in laboratories to clone genes and to express proteins; an overview on the plasmids of archaea and eukarya; bioinformatic tools; horizontal gene transfer and the process of DNA transfer. Two entire chapters are devoted to the important medical applications of plasmids, including the correction of gene defects and vaccines to treat cancer or infectious diseases. read more ... |
 | Edited by: Peter Kuhnert and Henrik Christensen Published: 2008 ISBN: 978-1-904455-34-9 Price: GB £150 or US $310 Pasteurella book. In this timely book, leading international Pasteurellaceae scientists critically review the most important current research providing an up-to-date review of the molecular biology, genomics and virulence of these fascinating organisms. Topics covered include taxonomy and biodiversity, phylogeny, comparative genomics, competence, DNA uptake and transformation, proteomics and protein secretion, RTX toxins, lipopolysaccharides, biofilms, quorum sensing, antimicrobial resistance, diagnosis, and OMP and iron uptake. Each chapter is independent and can be read in isolation and as a whole the book provides an important resource summarising our current knowledge of Pasteurellaceae genomics and molecular biology. Essential reading for everyone working on Pasteurellaceae and related organisms. read more ... |
 | Edited by: Shah M. Faruque and G. Balakrish Nair Published: 2008 ISBN: 978-1-904455-33-2 Price: GB £150 or US $310 In this book leading V. cholerae experts, the chapters review the most important cutting-edge genetic facets of V. cholerae including its genomic organization, population genetics, molecular epidemiology, and synchronized regulation of gene expression. Other topics include the molecular basis for enhanced transmissibility of cholera during epidemics, survival of the pathogen in the environment, and above all the evolution of the species to attain increased fitness both as a pathogen and an environmental organism. Essential reading for everyone with an interest in Vibrio and recommended reading for other scientists working in microbial pathogenesis, microbial genomics and antimicrobial research. read more ... |
 | Edited by: Gioconda San-Blas and Richard A. Calderone Published: 2008 ISBN: 978-1-904455-32-5 Price: GB £150 or US $310 In this book a panel of expert international mycologists critically review the most important cutting-edge topics. Chapters are written from a molecular and genomic perspective and through the provision of extensive reference sections positively encourage readers to pursue the subject in greater detail. Topics include: gene expression and regulation, heterozygosity in Candida, molecular diagnosis, regulation of the host-fungal interaction, the development of anti-fungals, signal transduction, and mechanisms of multi-drug resistance. read more ... |
 | Edited by: Yoshio Yamaoka Published: 2008 ISBN: 978-1-904455-31-8 Price: GB £150 or US $310 Helicobacter is leading cause of peptic ulcers, gastritis and gastric cancer worldwide, therefore has been the subject of intensive research. As the number of publications in this field has risen dramatically in recent years, it is extremely difficult for even the most diligent reader to stay abreast of progress. This book distills the most important cutting-edge findings in the field to produce a timely and comprehensive review. With contributions from leading international helicobacter researchers, topics include: lipopolysaccharides, outer membrane proteins, motility and chemotaxis, type IV secretions systems, metal metabolism, molecular mechanisms of host adaptation, genomotyping, and proteonomics. read more ... |
 | Edited by: Andreas Burkovski Published: 2008 ISBN: 978-1-904455-30-1 Price: GB £150 or US $310 Leading Corynebacteria experts provide a description of the current state-of-the-art molecular biology toolbox available for Corynebacterium research, including global analyses techniques such as comparative genomics, transcriptome, proteome and metabolome analysis as well as the most recent knowledge on Corynebacterium promoter structures and vector systems. Furthermore, topics such as regulatory networks controlling carbon, nitrogen, phosphorus, sulphur and iron metabolism, cell wall structure, proteolysis and environmental stress response are covered. Essential reading for all Corynebacterium scientists and everyone with an interest in global analysis techniques, global regulation and systems biology. read more ... |
 | Edited by: Jodi Lindsay Published: 2008 ISBN: 978-1-904455-29-5 Price: GB £150 or US $300 This volume, the first to focus on the stapyhlococcal genetics provides a state-of-the art overview of the field. Topics include the sequencing projects, including spin-off microarray and systems biology tools, epidemiology, evolution, manipulation of the genome, diagnostics, gene expression due to global regulators and environmental triggers, cell-wall synthesis, coagulase-negative species, and animal pathogens. It is designed for two major audiences. Firstly, to introduce the subject to new researchers, including those unfamiliar with genetics. Secondly, for established researchers, for whom it will serve as an invaluable reference and summary of a large field, as well as presenting the latest advances and future trends written by those who are developing them. read more ... |
 | Edited by: Peter J. Myler and Nicolas Fasel Published: 2008 ISBN: 978-1-904455-28-8 Price: GB £150 or US $300 In this book, internationally recognised Leishmania experts critically review the most important aspects of current Leishmania research, providing the first coherent picture of the organism's molecular and cellular biology since the publication of the genome sequence. Chapters are written from a molecular and genomic perspective and discuss in depth Leishmania-specific aspects of trypanosomatid biology and pathology. Topics include: diagnosis and epidemiology, genome structure and content, regulation of gene expression, the Leishmania proteome, the Leishmania metabolome, Leishmania differentiation, interaction with the sand fly vector, drug discovery, drug resistance, and much more. Essential reading for all researchers working with Leishmania, trypanosomes and protozoa. A recommended book for all biology and medical libraries. read more ... |
 | Edited by: Klaus Heuner and Michele Swanson Published: 2008 ISBN: 978-1-904455-26-4 Price: GB £150 or US $300 The current state of many of the most critical features of Legionella. Authors have contributed papers describing and discussing the latest research findings with an emphasis on molecular aspects. Recommended for all microbiology and clinical research laboratories. read more ... |
 | Edited by: Anthony H. Rogers Published: 2008 ISBN: 978-1-904455-24-0 Price: GB £150 or US $300 The molecular biology of micro-organisms involved in the two major dental diseases: caries and periodontal disease. Research has focused on factors which might modulate the interaction between the resident oral bacteria and the host. read more ... |
 | Edited by: Jörg Tost Published: 2008 ISBN: 978-1-904455-23-3 Price: GB £150 or US $300 The molecular mechanisms and biological processes in which epigenetic modifications play a primordial role are described in detail. read more ... |
 | Edited by: Thomas C. Mettenleiter and Francisco Sobrino Published: 2008 ISBN: 978-1-904455-22-6 Price: GB £150 or US $300 An international panel of leading virologists provide a state-of-the-art overview of the field, comprehensively detailing the current understanding of viruses, their replication, evolution and interaction with the host. read more ... |
 | Edited by: John T. Patton Published: 2008 ISBN: 978-1-904455-21-9 Price: GB £150 or US $300 This timely book brings together all of the key recent research on this disparate group of viruses, providing for the first time a single resource reviewing dsRNA viral structure and molecular biology. Written by well respected and experienced virologists, topics include: the structures of orthoreoviruses, rotavirus, phytoreoviruses, and bluetongue virus, entry into the bacterial cell, crystal structure of reovirus polymerase λ3, assembly of the reovirus genome, genomic RNA packaging and replication in the Cystoviridae, and much more. Essential reading for all dsRNA virologists and all other virologists with an interest in molecular and structural biology. read more ... |
 | Edited by: Ulrike Gerischer Published: 2008 ISBN: 978-1-904455-20-2 Price: GB £150 or US $300 Expert international authors have contributed chapters on diverse topics including taxonomy, lipopolysaccharides, catabolism of aromatic compounds, transformation systems, transcriptional regulation, applications in biotechnology, the molecular basis for virulence and pathogenicity, molecular epidemiology, and antibiotic resistance. This book is highly recommended for anyone involved in Acinetobacter research. read more ... |
 | Edited by: Pierre Cornelis Published: 2008 ISBN: 978-1-904455-19-6 Price: GB £150 or US $300 This concise volume reviews the most current and topical aspects of Pseudomonas molecular biology and genomics and is aimed at a readership of research scientists, graduate students and other specialists. Renowned international authors have contributed chapters on diverse topics including taxonomy, genome diversity, oligonucleotide usage, polysaccharides, pathogenesis, virulence, biofilms, antibiotic resistance and iron uptake. In addition an entire chapter is devoted to the genetic tools being developed to take full advantage of the wealth of information generated by the genome sequencing efforts. read more ... |
 | Edited by: Ian M. Mackay Published: 2007 ISBN: 978-1-904455-18-9 Price: GB £150 or US $300 This invaluable book describes and explains some of the more complex aspects of real-time PCR presenting a background for the novice, a theoretical reference for the experienced user, and useful discussions of future developments. Chapters address the basics of PCR history, oligonucleotide design, target preparation, standardisation, quantification, various applications, and future challenges. The final chapter is presented in the format of a roundtable discussion providing an insightful, topical and interesting discourse with contributions from over 30 authorities and experts on real-time PCR. read more ... |
 | Edited by: Volker Thiel Published: 2007 ISBN: 978-1-904455-16-5 Price: GB £75 or US $149 In this timely book, internationally renowned experts review literally every aspect of cutting edge coronavirus research providing the first coherent picture of the molecular and cellular biology since the outbreak of SARS in 2003. The book is divided into two sections: Part I focuses on the molecular biology of the virus itself and includes topics such as coronavirus binding and entry, replicase gene function, cis-acting RNA elements, coronavirus discontinuous transcription, reverse genetics, genome packaging and molecular evolution. In Part II of the book, the focus is on molecular and cellular pathogenesis and infection control. read more ... |
 | Edited by: Antonia Herrero and Enrique Flores Published: 2008 ISBN: 978-1-904455-15-8 Price: GB £150 or US $300 This volume brings together the expertise and enthusiasm of an international panel of leading cyanobacterial researchers to provide a state-of-the art overview of the field. Topics covered include: evolution, comparative genomics, gene transfer, molecular ecology and environmental genomics, stress responses, bioactive compounds, circadian clock, structure of the photosynthetic apparatus, membrane systems, carbon acquisition, nitrogen assimilation and C/N balance sensing and much more. Essential for anyone with an interest in cyanobacteria, bacterial photosynthesis, bacterial nitrogen fixation, and symbosis. read more ... |
 | Edited by: Christophe d'Enfert and Bernhard Hube Published: 2007 ISBN: 978-1-904455-13-4 Price: GB £150 or US $300 International experts provide comprehensive and authoritative reviews of current research on Candida. Essential reading for all Candida genome and molecular biology researchers and a recommended text for scientists working on fungal genomics and molecular biology. read more ... |
 | Edited by: Wayne Koff, Patricia Kahn and Ian D. Gust Published: 2007 ISBN: 978-1-904455-11-0 Price: GB £49 or US $99 Reviews the scientific challenges that have impeded the search for an effective AIDS vaccine and discusses current novel research that is accelerating progress. In a series of mini-reviews by the worlds leading experts in AIDS vaccine research the book is essential reading for everyone interested in the current progress and future direction of AIDS vaccine development. read more ... |
 | Edited by: Justin D. Radolf and Sheila A. Lukehart Published: 2006 ISBN: 978-1-904455-10-3 Price: GB £69 or US $139 The focus of the book is on recent advances and new developments in Treponema research, in particular those resulting from modern molecular and genetic methodologies. Topics covered include the phylogenic diversity, comparative genomics, metabolism and cultivation, motility, antigenic variation, immunology of syphilis, the use cultivatable treponemes as surrogates for T. pallidum, oral treponemes, and much much more. read more ... |
 | Edited by: R. M. Sandri-Goldin Published: 2006 ISBN: 978-1-904455-09-7 Price: GB £140 or US $280 The alpha herpesviruses are an important group of viruses. In this timely book internationally recognized experts, highlight the more provocative and exciting findings in herpesvirus research. Each chapter is a review of a specific area with an emphasis on recent advances and the latest developments. Topics include: multifunctional proteins, advances in DNA replication, new information on the regulation of gene expression, the emergence of new technologies, recent technological advances in fluorescent probes, the induction of apoptosis, the disruption of interferon, vaccine development and drug design. read more ... |
 | Author: Michael L. Altshuler Published: 2006 ISBN: 978-1-904455-07-3 Price: GB £30 or US $60 A unique PCR troubleshooting guide that is an essential companion for anyone who uses the polymerase chain reaction technique. read more ... |
 | Edited by: Yoshihiro Kawaoka Published: 2006 ISBN: 978-1-904455-06-6 Price: GB £130 or US $260 Influenza Virology: Current Topics. Topics covered include analysis of influenza RNP, viral entry and intracellular transport, epidemiology, host range and pathogenicity, antivirals, vaccines, H5 viruses. read more ... |
 | Edited by: Peter J. Lachmann Published: 2006 ISBN: 978-1-904455-05-9 Price: GB £115 or US $230 Microbial Subversion of Immunity: Current Topics. Topics covered include the subversion of complement, NK cell function, mucosal innate immune response, antigenic variation, masking of epitopes, the use of decoys, molecular mimicry, evasion/subversion mechanisms used by bacteria, helminths, viruses, and the measles model system. read more ... |
 | Edited by: M. Saveria Campo Published: 2006 ISBN: 978-1-904455-04-2 Price: GB £150 or US $300 In this timely book leading scientists review current aspect of papillomavirus research providing a fascinating insight into papillomavirus molecular biology, interactions with the host, immunology and vaccine development. Topics covered include epidemiology and taxonomy, phylogenetic analyses, gene expression, regulation of DNA replication, transcription factor proteins, organotypic raft cultures, virus-like particles, and much more. Essential reading for scientists and researchers working on papillomavirus and a recommended text for anyone involved with antiviral drug and vaccine development. read more ... |
 | Edited by: Caister Academic Press Editor: Erle S. Robertson Published: 2005 ISBN: 978-1-904455-03-5 Price: GB £150 or US $300 World renowned EBV experts provide a critical and comprehensive review of every aspect of this important virus. By integrating genetic, immunologic, and cell biologic approaches to elucidate pathogenesis, penetrating new insights into the molecular and cellular interaction between EBV and its human host have emerged. Topics covered include: Discovery, history and seroepidemiology, EBV and the immune response, EBV genetics, EBV infection and persistence, latency, lytic proteins and reactivation control, vaccine approaches, animal models, and the future of EBV studies. This is essential reading for all EBV virologists as well as clinical and research scientists working on oncogenic viruses. read more ... |
 | Edited by: Matthias J. Reddehase Published: 2006 ISBN: 978-1-904455-02-8 Price: GB £140 or US $280 Leading international experts provide comprehensive and authoritative reviews on every aspect of current research. By integrating viral genomics, proteomics, immunology and molecular biology with the emerging knowledge of the genomics of the host organism, penetrating new insights into the virus-host interaction are provided. The focus of the book is on the molecular and genomic aspects and the authors provide an insight into the current understanding of the subject and the future direction of research. Topics covered include disease mechanisms, genomics, proteomics, BAC mutagenesis, virus entry and activation of innate immunity, regulation of viral gene expression, regulation of viral mRNA export, animal models of infection, novel therapeutics, vaccine development, antivirals, and much more. read more ... |
 | Edited by: Gerald W. Tannock Published: 2005 ISBN: 978-1-904455-01-1 Price: GB £99 or US $199 Food scientists and nutritionists have accepted, relatively uncritically, the concepts underlying the use of probiotics and prebiotics in the promotion of health. Microbiologists and medical practitioners have viewed these products more sceptically. Much more scientific and medical validation of probiotic or prebiotic use is required. This will entail the use of sophisticated analytical methodologies. Knowledge of the gut microbiota has increased dramatically during the past decade thanks largely to the results obtained from the application of nucleic acid-based methodologies. Because of the availability of improved technologies, detailed studies of the two principal kinds of probiotic or prebiotic bacteria, Lactobacillus and Bifidobacterium, can be made. Emerging leaders have contributed chapters to this book that therefore represents a state of the art compendium of fundamental science related to early 21st century probiotic or prebiotic research. read more ... |
 | Edited by: Pina M. Fratamico, Arun K. Bhunia, and James L. Smith Published: 2005 ISBN: 978-1-904455-00-4 Price: GB £149 or US $299 Written by leaders in the field, this book represents a cutting edge summary of all the latest advances, providing the first coherent picture of the current status. Opening chapters tackle topics such as pathogen detection (molecular, biosensor), molecular typing, viable but non-culturable organisms, predictive modeling, and stress responses. The next section covers groups of organisms: enteric viruses, protozoan parasites, and mycotoxins. This is followed by chapters on specific bacteria: Yersinia enterocolitica, Vibrio spp., Staphylococcus aureus, Campylobacter Infections, Listeria monocytogenes, Salmonella spp., Shigella spp., Escherichia coli, Clostridium botulinum, Clostridium perfringens and Bacillus cereus. The final chapters provide a fascinating review of the ability of pathogens to contaminate a food supply and provide an overview of emerging foodborne pathogens. read more ... |
 | Edited by: Pina M. Fratamico, Arun K. Bhunia, and James L. Smith Published: 2008 ISBN: 978-1-898486-52-7 Price: GB £99 or US $199 Written by leaders in the field, this book represents a cutting edge summary of all the latest advances, providing the first coherent picture of the current status. Opening chapters tackle topics such as pathogen detection (molecular, biosensor), molecular typing, viable but non-culturable organisms, predictive modeling, and stress responses. The next section covers groups of organisms: enteric viruses, protozoan parasites, and mycotoxins. This is followed by chapters on specific bacteria: Yersinia enterocolitica, Vibrio spp., Staphylococcus aureus, Campylobacter Infections, Listeria monocytogenes, Salmonella spp., Shigella spp., Escherichia coli, Clostridium botulinum, Clostridium perfringens and Bacillus cereus. The final chapters provide a fascinating review of the ability of pathogens to contaminate a food supply and provide an overview of emerging foodborne pathogens. read more ... |
 | Edited by: Salvatore T. Butera Published: 2005 ISBN: 978-0-9542464-9-5 Price: GB £110 or US $220 Expert AIDS researchers critically review every aspect of this highly topical subject. Chapters deal with the management of HIV infections, strategies to protect and strengthen the host immune system at the cellular level, strategies required for the implementation of effective anti-HIV therapies in developing countries, the genetics of viral drug resistance, current drug-resistance testing technologies, the latest viral and cellular targets for anti-HIV chemotherapy, the development of iRNA based therapeutics and molecular based strategies that target latent virus reservoirs in infected individuals. Essential reading for scientists and clinicians working on AIDS, HIV, and other retroviruses as well as all health care professionals interested in expanding their current understanding of the subject. read more ... |
 | Edited by: Gioconda San-Blas and Richard A. Calderone Published: 2004 ISBN: 978-0-9542464-8-8 Price: GB £99 or US $199 This book, together with its companion volume "Pathogenic Fungi: Structural Biology and Taxonomy", brings together expert international authors who critically review current topics, and through the provision of extensive reference sections positively encourage readers to pursue the subject in greater detail. The book is divided into two sections: "Fungal Interactions with the Host" and "Antifungal Antibiotics". The emphasis of the first section is focused on the two-way recognition systems that exist between the host and the fungus. Experts in fungal-host interactions discuss new initiatives for alternatives to drug therapy through the development of vaccines and passive antibody therapy. In the "Antifungal Antibiotics" section, new target development, molecular modelling, and drug resistance, both at the individual organism level, and in a biofilm, are featured. read more ... |
 | Edited by: Gioconda San-Blas and Richard A. Calderone Published: 2004 ISBN: 978-0-9542464-7-1 Price: GB £99 or US $199 Expert international authors critically review current topics and positively encourage readers to pursue the subject in greater detail.The book is divided into two sections: "Fungal Dimorphism and Pathogenicity" and "New Taxonomic Tools". The first section focuses on morphogenesis, the cell cycle, and the cell wall of human pathogens. These play a major role in elucidating fungal relationships, both with the environment and with the host. Experts in fungal structural biology contribute in-depth reviews on a variety of topics with a focus on molecular and biochemical analysis. The final chapter presents a review of how mathematical modelling is used to understand the building of three-dimensional cell structures in the morphogenetic process. The second section presents novel approaches to aid the understanding of strain variability, the significance of environmental and patient strains, and the relatedness of "uncultured" fungi. In addition the use of molecular tools forthe taxonomic classification of previously unclassifiable fungi is featured. read more ... |
 | Edited by: A.P. Waters and C.J. Janse Published: 2004 ISBN: 978-0-9542464-6-4 Price: GB £115 or US $230 The completion of the Plasmodium falciparum genome sequence in late 2002 hearlded a new era in malaria research. The search could begin in earnest for new drugs and vaccines to combat malaria, a disease which afflicts up to 500 million people worldwide and is responsible for the deaths of more than one million people each year. More importantly, it should enable a greater understanding of the living parasite and it's interaction with the insect vector and human host. In this book internationally renown experts provide up to date reviews of the most important aspects of post-genomic malaria research. Topics covered include: the P. falciparum genome and model parasites, bioinformatics and genome databases, microsatellite analysis, analysis of chromosome structure, cell cycle to RNA polymerase I and II mediated gene expression, role of the nuclear genome, the parasite surface and cell biology, and much much more. read more ... |
 | Edited by: Ad C. Fluit and Franz-Josef Schmitz Published: 2003 ISBN: 978-0-9542464-5-7 Price: GB £90 or US $180 Methicillin-resistant S. aureus (MRSA) strains continue to present unique challenges to clinicians, microbiologists, and the molecular biologists around the world. These organisms are typically resistant to several other antimicrobial agents, including aminoglycosides, chloramphenicol, clindamycin, fluoroquinolones and macrolides and are susceptible only to vancomycin. Internationally renown authors comprehensively review all aspects of MRSA research. Topics covered include strategies for the detection and typing of MRSA strains, epidemiological characterisation, molecular evolution of MRSA, vancomycin resistant S. aureus, mechanisms of methicillin resistance, virulence mechanisms in MRSA pathogenesis, recommended treatment of MRSA infections and options for the prevention and control of MRSA infections. read more ... |
 | Edited by: Antoine Danchin Published: 2002 ISBN: 978-0-9542464-3-3 Price: GB £75 or US $150 Eminent scientists have contributed comprehensive reviews on all aspects of the genomics of Rhodococcus, Mycobacteria, Streptomyces and other organisms. The authors provide an insight into the many facets of large-scale functional investigation in a variety of bacteria with the explicit goal to find common rules in the dynamic and structural organisation of these organisms. This volume is the definitive guide to current research in this increasingly important area. read more ... |
 | Edited by: Gerald W. Tannock Published: 2002 ISBN: 978-0-9542464-1-9 Price: GB £90 or US $180 Contains state-of-the-art commentaries on all aspects of the intestinal microflora and probiotics and provides an authoritative review of important aspects of probiotic and prebiotic research. Written by leading experts in the field, each chapter affords a critical insight to a particular topic, reviews current research, discusses future direction and aims to stimulate discussion. Topics covered include the genomics of probiotic microorganisms, the developing technologies for analysis of gut microorganisms, evaluation and future potential of prebiotic substances, and the potential for disease prevention in the host by probiotic organisms. read more ... |