Molecular Biology Books

PCR Troubleshooting and Optimization: The Essential GuideEdited by: Suzanne Kennedy and Nick Oswald
Published: 2011   ISBN: 978-1-904455-72-1
Price: GB £159 or US $310
Strategies for preparing effective controls and standards for PCR, when they should be employed and how to interpret the information they provide. The significance of optimization for efficiency, precision and sensitivity of PCR methodology and essential guidance on how to troubleshoot inefficient reactions. Design and optimization techniques, the use of appropriate controls, the significance of standard curves and the principles and strategies required for effective troubleshooting. The importance of sample preparation and quality, primer design, controlling inhibitors, avoiding amplicon and environmental contamination, optimizing reagent quality and concentration, and modifying the thermal cycling protocol for optimal sensitivity and specificity. read more ...
Molecular Phylogeny of MicroorganismsEdited by: Aharon Oren and R. Thane Papke
Published: 2010   ISBN: 978-1-904455-67-7
Price: GB £159 or US $310
Current concepts in molecular phylogeny and their application with respect to microorganisms. The different approaches applied to elucidate the molecular phylogeny of prokaryotes; reviews of current phylogenetic methods, techniques and software tools. Topics include a historical overview, computational tools, multilocus sequence analysis, 16S rRNA phylogenetic trees, rooting of the universal tree of life, applications of conserved indels, lateral gene transfer, endosymbiosis and the evolution of plastids. read more ...
Nanotechnology in Water Treatment ApplicationsEdited by: T. Eugene Cloete, Michele de Kwaadsteniet, Marelize Botes and J. Manuel López-Romero
Published: 2010   ISBN: 978-1-904455-66-0
Price: GB £159 or US $310
Reviews the current state-of-the-art research and development of different nanomaterials (nanostructured catalytic membranes, nanosorbents, nanocatalysts and bioactive nanoparticles) and their application in water treatment, purification and disinfection. The expert authors have contributed chapters focusing on the cutting-edge research in this emerging technology and its applications in microbiology and water treatment. Topics covered include the detection of microbial pathogens, nanofibers and nanobiocides in water purification, nanozymes for biofilm removal, water and wastewater treatment and reverse osmosis. read more ...
Microbial Population GeneticsEdited by: Jianping Xu
Published: 2010   ISBN: 978-1-904455-59-2
Price: GB £159 or US $310
Major current advances in microbial population genetics and genomics. Fundamental concepts, genetic tools and comprehensive reviews of recent data from SNP surveys, whole-genome DNA sequences and microarray hybridizations. Covers broad groups of microorganisms including viruses, bacteria, archaea, fungi, protozoa and algae. A major focus is the application of molecular tools in the study of genetic variation. Topics include microbial systematics, comparative microbial genomics, horizontal gene transfer, pathogenic bacteria, nitrogen-fixing bacteria, cyanobacteria, microalgae, fungi, malaria parasites, viral pathogens and metagenomics. read more ...
RNA Interference and Viruses: Current Innovations and Future TrendsEdited by: Miguel Angel Martínez
Published: 2010   ISBN: 978-1-904455-56-1
Price: GB £159 or US $310
In this book, expert RNAi specialists from around the world have teamed up to produce a timely and thought-provoking review of the area. The two central themes are the latest findings on RNAi-virus interactions and the current progress in the development of RNAi-based antiviral therapeutics. A number of chapters explain general concepts concerned with the role of RNAi in natural antiviral defense mechanisms, other chapters discuss how to improve the efficacy and safety of RNAi-based antiviral drugs, while others describe how this technology is being developed as a new therapeutic tool for fighting specific viruses, including HIV, HCV and respiratory viruses. Authors also outline potential new avenues for research thus providing a stimulus for further research. read more ...
Metagenomics: Theory, Methods and ApplicationsEdited by: Diana Marco
Published: 2010   ISBN: 978-1-904455-54-7
Price: GB £159 or US $310
The diverse and multiple aspects of metagenomics and the multiplicity of its potential applications. The new theoretical insights, the more recent applications, and the dynamically developing methods of data acquisition and analysis. Essential reading for all researchers wishing to broaden their knowledge of metagenomics and highly recommended for those new to the field. read more ...
Lab-on-a-Chip Technology: Biomolecular Separation and AnalysisEdited by: Keith E. Herold and Avraham Rasooly
Published: 2009   ISBN: 978-1-904455-47-9
Price: GB £150 or US $310
Applications of lab-on-a-chip devices in biotechnology, medicine, clinical diagnostics, chemical engineering, and pharmaceutics. Various electrophoresis and liquid chromatography applications, methods for cell separation, blood cell separation, clinical applications, protein, genetic, PCR, transcriptome analysis, cell manipulation and analysis, cell viability analysis, microorganism capturing. read more ...
Lab-on-a-Chip Technology: Fabrication and MicrofluidicsEdited by: Keith E. Herold and Avraham Rasooly
Published: 2009   ISBN: 978-1-904455-46-2
Price: GB £150 or US $310
Current lab-on-a-chip technologies including theoretical and technical information for the understanding of the technology and the reproduction of experiments. Will help the understanding of current LOC technologies, performance of similar experiments, the design of new LOC systems and development of new methodologies and applications. read more ...
Real-Time PCR: Current Technology and ApplicationsEdited by: Julie Logan, Kirstin Edwards and Nick Saunders
Published: 2009   ISBN: 978-1-904455-39-4
Price: GB £150 or US $310
A comprehensive guide to the most up-to-date real-time PCR technology and applications. The latest PCR platforms, fluorescent chemistries, validation software, data analysis, internal and external controls,clinical diagnostics, biodefense, RNA expression studies, validation of array data, mutation detection, food authenticity and legislation, NASBA, molecular halotyping. read more ...
Plant Pathogenic Bacteria: Genomics and Molecular BiologyEdited by: Robert W. Jackson
Published: 2009   ISBN: 978-1-904455-37-0
Price: GB £150 or US $310
In this book, internationally acclaimed experts review the most important developments providing an invaluable, up-to-date summary of the molecular biology and genomics of plant pathogenic bacteria. The book opens with two chapters on bacterial evolution, diversity and taxonomy, topics that have been transformed by molecular biology and genomics analyses. The third chapter delves into the crucially understudied area of pathogen adaptation to the plant apoplast environment. The following seven chapters focus on specific plant pathogens: Agrobacterium, Leifsonia, Pectobacterium, Pseudomonas, Ralstonia, Xanthomonas, and Xylella. The next four chapters review specific, intensively studied areas of research in the plant pathogen field: microbe associated molecular patterns (MAMPs) and innate immunity; use of bacterial virulence factors to suppress plant defence; cyclic di-GMP signalling and the regulation of virulence; and plasmids and the spread of virulence. The final chapter covers the critical area of bioinformatics. read more ...
Microbial Production of Biopolymers and Polymer Precursors: Applications and PerspectivesEdited by: Bernd H. A. Rehm
Published: 2009   ISBN: 978-1-904455-36-3
Price: GB £150 or US $310
Describes in detail the use of microorganisms for the production of the most important biopolymers and polymer precursors. The authors describe, in depth, the biosynthetic pathways, physical properties and industrial production processes and discuss in detail the genetic and metabolic engineering of microorganisms for biopolymer production. Also highlighted are the applications and potential applications of the biopolymers and microbial biotechnology read more ...
RNA and the Regulation of Gene Expression: A Hidden Layer of ComplexityEdited by: Kevin V. Morris
Published: 2008   ISBN: 978-1-904455-25-7
Price: GB £150 or US $300
Experts in RNA research explore and discuss the methods whereby RNA can regulate gene expression with examples in yeast, Drosophila, mammals, and viral infection, and highlight the application of this knowledge in therapeutics and research. read more ...
EpigeneticsEdited by: Jörg Tost
Published: 2008   ISBN: 978-1-904455-23-3
Price: GB £150 or US $300
The molecular mechanisms and biological processes in which epigenetic modifications play a primordial role are described in detail. read more ...
Real-Time PCR in Microbiology: From Diagnosis to CharacterizationEdited by: Ian M. Mackay
Published: 2007   ISBN: 978-1-904455-18-9
Price: GB £150 or US $300
This invaluable book describes and explains some of the more complex aspects of real-time PCR presenting a background for the novice, a theoretical reference for the experienced user, and useful discussions of future developments. Chapters address the basics of PCR history, oligonucleotide design, target preparation, standardisation, quantification, various applications, and future challenges. The final chapter is presented in the format of a roundtable discussion providing an insightful, topical and interesting discourse with contributions from over 30 authorities and experts on real-time PCR. read more ...
PCR Troubleshooting: The Essential GuideAuthor: Michael L. Altshuler
Published: 2006   ISBN: 978-1-904455-07-3
Price: GB £30 or US $60
A unique PCR troubleshooting guide that is an essential companion for anyone who uses the polymerase chain reaction technique. read more ...
Frontiers in Computational GenomicsEdited by: Michael Y. Galperin and Eugene V. Koonin
Published: 2003   ISBN: 978-0-9542464-4-0
Price: GB £90 or US $180
Computational biology and bioinformatics form a major, integral part of genomics. From sequence fragment assembly, to gene prediction, to prediction of protein functions and structure, to identification of regulatory signals in DNA, to building phylogenetic trees, it would not be an exaggeration to state that genomics is primarily computational. Major new programs, software and internet facilities have evolved recently that facilitate computational analysis and more novel technologies are currently being developed. Written by experts in the field, this volume highlights research on the emerging, perhaps somewhat controversial, topics in genomics and shows the feedback between the new developments and the established methods of computational biology. An essential book for anyone involved in genomic science or bioinformatics. read more ...
Genomics of GC-Rich Gram-Positive BacteriaEdited by: Antoine Danchin
Published: 2002   ISBN: 978-0-9542464-3-3
Price: GB £75 or US $150
Eminent scientists have contributed comprehensive reviews on all aspects of the genomics of Rhodococcus, Mycobacteria, Streptomyces and other organisms. The authors provide an insight into the many facets of large-scale functional investigation in a variety of bacteria with the explicit goal to find common rules in the dynamic and structural organisation of these organisms. This volume is the definitive guide to current research in this increasingly important area. read more ...
Genomic Technologies: Present and FutureEdited by: David J. Galas
Published: 2002   ISBN: 978-0-9542464-2-6
Price: GB £90 or US $180
The chapters in this book reflect the range of technical advances and their applications that are currently transforming biology. Topics covered include the application of computational methods, the robotics of modern automation methodologies, the new chemical and imaging methods that reveal chromosome structure and elucidate gene function, and the emergence of evolutionary and functional information by comparative genomics. Eminent international scientists describe in detail the new technology necessary to study the entire genome in a holistic manner and all the high throughput and large-scale experimental methodologies currently being used in genomic science. In addition the authors describe the progress of the newest technologies that are currently being developed. read more ...