Molecular Microbiology Books

Hepatitis C: Antiviral Drug Discovery and DevelopmentEdited by: Seng-Lai Tan and Yupeng He
Published: 2011   ISBN: 978-1-904455-78-3
Price: GB £180 or US $350
In-depth reviews of the most critical areas of HCV research. Includes the HCV life cycle, HCV assays, HCV resources, HCV databases, HCV infection systems, models of hepatitis C infections, overview of the drug pipeline, clinical trial design, clinical virology and drug development, NS3 protease inhibitors, NS3-NS4A complex inhibitors, NS3 helicase inhibitors, NS4B targets and inhibitors, NS5A inhibitors, nucleoside inhibitors, NS5B polymerase inhibitors, glycoprotein-dependent entry, host cell targets and inhibitors, and innate immunity for HCV antiviral therapy. read more ...
Streptomyces: Molecular Biology and BiotechnologyEdited by: Paul Dyson
Published: 2011   ISBN: 978-1-904455-77-6
Price: GB £159 or US $310
Documents recent research and development in streptomycetes genomics, physiology and metabolism. An excellent source of up-to-date information. Topics include: genome architecture, conjugative genetic elements, differentiation, protein secretion, central carbon metabolic pathways, regulation of nitrogen assimilation, phosphate control of metabolism, gamma-butyrolactones and their role in antibiotic regulation, clavulanic acid and clavams, genome-guided exploration, gene clusters for bioactive natural products, genomics of cytochromes p450. read more ...
Alphaherpesviruses: Molecular VirologyEdited by: Sandra K. Weller
Published: 2011   ISBN: 978-1-904455-76-9
Price: GB £180 or US $350
This up-to-date and comprehensive volume aims to distill the most important research on alphaherpesvirus molecular virology providing a timely overview of the field. Topics covered include: transcriptional regulation, DNA replication, translational control, virus entry and capsid assembly, the role of microRNAs in infection and oncolytic vectors for cancer therapy. In addition there is coverage of virus-host interactions, including apoptosis, subversion of host protein quality control and DNA damage response pathways, autophagy, establishment and reactivation from latency, interferon responses, immunity and vaccine development. Essential reading for everyone working with alphaherpesviruses and of interest to all virologists working on latent infections. read more ...
Recent Advances in Plant VirologyEdited by: Carole Caranta, Miguel A. Aranda, Mark Tepfer and J.J. Lopez-Moya
Published: 2011   ISBN: 978-1-904455-75-2
Price: GB £180 or US $350
This book attests to the huge diversity of research in plant molecular virology. Written by world authorities in the field, the book opens with two chapters on the translation and replication of viral RNA. Following chapters cover topics such as viral movement within and between plants, plant responses to viral infection, antiviral control measures, virus evolution, and newly emerging plant viruses. To close there are two chapters on biotechnological applications of plant viruses. Throughout the book the focus is on the most recent, cutting-edge research, making this book essential reading for everyone, from researchers and scholars to students, working with plant viruses. read more ...
Vaccine Design: Innovative Approaches and Novel StrategiesEdited by: Rino Rappuoli and Fabio Bagnoli
Published: 2011   ISBN: 978-1-904455-74-5
Price: GB £180 or US $350
The book has been divided into two parts. The first part reviews the technologies and approaches used to identify, generate and test new vaccines. Topics include: new strategies to identify protective antigens, generation of improved adjuvants, use of alternative immunization routes, improving vaccine safety, and finding and establishing the correlates of protection. The second part of the book focuses on the development of new vaccines to replace or complement currently available products or for diseases against which prophylactic strategies are missing. Examples include vaccines against nosocomial infections, streptococci, emerging viral diseases, P. aeruginosa, and bovine mastitis. Essential reading for everyone with an interest in vaccine research. read more ...
Salmonella: From Genome to FunctionEdited by: Steffen Porwollik
Published: 2011   ISBN: 978-1-904455-73-8
Price: GB £159 or US $310
In this book, internationally acclaimed experts review cutting-edge topics in Salmonella genomics and molecular biology. Topics include latest approaches to sub-species level classification and phage typing of Salmonella, comparative genomics, the search for genetic determinants for survival of the bacterium in different environments and the evolution of niche specialization by Salmonella. The book also explores the latest genomic information and molecular characterizations of sRNAs and complements of fimbriae, flagella and secreted virulence factors. Moreover, S. Typhi pathogenesis, interactions of the host with intracellular Salmonella and the host's anti-Salmonella immune response are reviewed. The current knowledge on Salmonella biofilm formation and a progress report on using Salmonella as an anti-tumour tool conclude this compendium. read more ...
PCR Troubleshooting and Optimization: The Essential GuideEdited by: Suzanne Kennedy and Nick Oswald
Published: 2011   ISBN: 978-1-904455-72-1
Price: GB £159 or US $310
Strategies for preparing effective controls and standards for PCR, when they should be employed and how to interpret the information they provide. The significance of optimization for efficiency, precision and sensitivity of PCR methodology and essential guidance on how to troubleshoot inefficient reactions. Design and optimization techniques, the use of appropriate controls, the significance of standard curves and the principles and strategies required for effective troubleshooting. The importance of sample preparation and quality, primer design, controlling inhibitors, avoiding amplicon and environmental contamination, optimizing reagent quality and concentration, and modifying the thermal cycling protocol for optimal sensitivity and specificity. read more ...
Insect VirologyEdited by: Sassan Asgari and Karyn N. Johnson
Published: 2010   ISBN: 978-1-904455-71-4
Price: GB £180 or US $350
Written by internationally renowned insect virologists, chapters cover all of the major groups of insect pathogenic viruses and suggest future directions for research. The book is divided into three parts: 1) DNA viruses 2) RNA viruses and 3) current hot-topics in insect virology. Virus groups covered include: Ascoviruses, Baculoviruses, Densoviruses, Entomopoxviruses, Hytrosaviruses, Iridoviruses, Nudiviruses, Polydnaviruses, Dicistroviruses, Iflaviruses, Nodaviruses, Tetraviruses and Cypoviruses. The special topics chapters review exciting recent developments in insect virology including RNAi, insect antiviral responses, structural comparison of insect RNA viruses, and viral ecology. The book is essential reading for every insect virologist in both the academic and private sectors. It is also strongly recommended for other virologists, particularly those interested in virus evolution, virus structure, viral vectors, biological control of insects and insect immunity. read more ...
Environmental Microbiology: Current Technology and Water ApplicationsEdited by: Keya Sen and Nicholas J. Ashbolt
Published: 2010   ISBN: 978-1-904455-70-7
Price: GB £159 or US $310
Current technology and its applications in water microbiology, the topics and techniques are equally applicable to all branches of environmental microbiology. The initial chapters cover the concentration, detection and characterization of microbes in drinking water, other chapters are technology focused and cover topics such as geochips and microarrays and their applications, Raman microspectroscopy and related single cell techniques, the use of amoebae hosts, bacteria and bacteriophage as bioreporters, viability of detected microbes and fecal source tracking. The value of the book emanates from its explanation of principles and the comparison of related techniques. read more ...
Sensory Mechanisms in Bacteria: Molecular Aspects of Signal RecognitionEdited by: Stephen Spiro and Ray Dixon
Published: 2010   ISBN: 978-1-904455-69-1
Price: GB £159 or US $310
The book opens with an introductory chapter that reviews the diversity of signal recognition mechanisms, illustrating the breadth of the field. Subsequent chapters include descriptions of the sensing of ligands (alpha-ketoglutarate, adenylate energy charge, glutamine and xenobiotic compounds), chemoreceptors, iron-sulfur cluster-based sensors, metal-dependent and metal-responsive sensors, thiol-based sensors, and PDZ domains as sensors of other proteins. This book provides essential reading for everyone with an interest in sensory mechanisms, regulatory networks and responses to environmental stress in bacteria. read more ...
Bifidobacteria: Genomics and Molecular AspectsEdited by: Baltasar Mayo and Douwe van Sinderen
Published: 2010   ISBN: 978-1-904455-68-4
Price: GB £159 or US $310
This book brings together the expertise and enthusiasm of the leading bifidobacteria experts from around the world to provide a state-of-the art overview of the molecular biology and genomics of this exciting and important microbial genus. Topics include: ecology, genomics, comparative genomics, metabolism, acid and bile resistance, stress response, probiotic properties, antimicrobial activity, interaction with the intestinal mucosa, safety assessment of bifidobacteria, synthesis and utilization of exopolysaccharides and prebiotics, antibiotic resistance/susceptibility profiles, viability and stability in commercial preparations, mobile genetic elements, cloning vectors and genetic manipulation of bifidobacteria. Essential reading for every bifidobacteria researcher, from the PhD student to the experienced scientist, and recommended reading for everyone with an interest in probiotics. read more ...
Molecular Phylogeny of MicroorganismsEdited by: Aharon Oren and R. Thane Papke
Published: 2010   ISBN: 978-1-904455-67-7
Price: GB £159 or US $310
Current concepts in molecular phylogeny and their application with respect to microorganisms. The different approaches applied to elucidate the molecular phylogeny of prokaryotes; reviews of current phylogenetic methods, techniques and software tools. Topics include a historical overview, computational tools, multilocus sequence analysis, 16S rRNA phylogenetic trees, rooting of the universal tree of life, applications of conserved indels, lateral gene transfer, endosymbiosis and the evolution of plastids. read more ...
Nanotechnology in Water Treatment ApplicationsEdited by: T. Eugene Cloete, Michele de Kwaadsteniet, Marelize Botes and J. Manuel López-Romero
Published: 2010   ISBN: 978-1-904455-66-0
Price: GB £159 or US $310
Reviews the current state-of-the-art research and development of different nanomaterials (nanostructured catalytic membranes, nanosorbents, nanocatalysts and bioactive nanoparticles) and their application in water treatment, purification and disinfection. The expert authors have contributed chapters focusing on the cutting-edge research in this emerging technology and its applications in microbiology and water treatment. Topics covered include the detection of microbial pathogens, nanofibers and nanobiocides in water purification, nanozymes for biofilm removal, water and wastewater treatment and reverse osmosis. read more ...
Iron Uptake and Homeostasis in MicroorganismsEdited by: Pierre Cornelis and Simon C. Andrews
Published: 2010   ISBN: 978-1-904455-65-3
Price: GB £159 or US $310
An international team of authors presents a comprehensive collection of reviews on iron uptake and metabolism in various microorganisms including Rhizobia, Bordetella, Shigella, E. coli, Erwinia, Vibrio, Aeromonas, Francisella, Bacteroides, Campylobacter, Cyanobacteria, Bacillus, Staphylococci and yeasts. An entire chapter is dedicated to siderophores and another to heme uptake. The volume provides an expert and timely summary of current knowledge, with a focus on molecular and genetic aspects, and highlights some of the most exciting recent developments. Aimed at research scientists, advanced students and other specialists, this book is highly recommended for everyone interested in iron uptake and metabolism, microbial pathogenesis and microbial ecology. read more ...
Caliciviruses: Molecular and Cellular VirologyEdited by: Grant S. Hansman, Xi Jason Jiang and Kim Y. Green
Published: 2010   ISBN: 978-1-904455-63-9
Price: GB £159 or US $310
In this book, a panel of expert calicivirologists have selected the most important up-to-date research findings to produce timely and comprehensive reviews of the respective calicivirus field. Each chapter gives the reader a brief introduction to the topic followed by a descriptive discussion of the past and present research areas. Topics include: norovirus epidemiology; calicivirus contamination of the environment; genome organization and recombination, proteolytic cleavage and viral proteins; viral protein structures; virus-host interactions; calicivirus reverse genetics and replicon systems; feline calicivirus; swine calicivirus; murine norovirus pathogenesis and immunity; murine norovirus translation, replication and reverse genetics; and lagoviruses. read more ...
Anaerobic Parasitic Protozoa: Genomics and Molecular BiologyEdited by: C. Graham Clark, Patricia J. Johnson and Rodney D. Adam
Published: 2010   ISBN: 978-1-904455-61-5
Price: GB £159 or US $310
In this book internationally acclaimed researchers critically review the most important aspects of research on anaerobic parasitic protozoa, providing the first coherent picture of their genomics and molecular biology since the publication of the genomes. Chapters are written from a molecular and genomic perspective and contain speculative models upon which future research efforts can be based. read more ...
Lentiviruses and Macrophages: Molecular and Cellular InteractionsEdited by: Moira Desport
Published: 2010   ISBN: 978-1-904455-60-8
Price: GB £159 or US $310
In this timely book, top lentivirus and macrophage specialists comprehensively review cutting-edge topics in the molecular and cellular biology of the lentivirus-macrophage interaction. Topics include lentivirus tropism and disease, macrophage biology, macrophage in HIV-1 infection and disease progression, post-entry restrictions to lentiviral replication, HIV-2 tropism and disease, SHIV model of disease, the felid immunodeficiency viruses, EIAV, small ruminant lentiviruses, bovine lentiviruses, coinfections and superinfections. read more ...
Microbial Population GeneticsEdited by: Jianping Xu
Published: 2010   ISBN: 978-1-904455-59-2
Price: GB £159 or US $310
Major current advances in microbial population genetics and genomics. Fundamental concepts, genetic tools and comprehensive reviews of recent data from SNP surveys, whole-genome DNA sequences and microarray hybridizations. Covers broad groups of microorganisms including viruses, bacteria, archaea, fungi, protozoa and algae. A major focus is the application of molecular tools in the study of genetic variation. Topics include microbial systematics, comparative microbial genomics, horizontal gene transfer, pathogenic bacteria, nitrogen-fixing bacteria, cyanobacteria, microalgae, fungi, malaria parasites, viral pathogens and metagenomics. read more ...
Borrelia: Molecular Biology, Host Interaction and PathogenesisEdited by: D. Scott Samuels and Justin D. Radolf
Published: 2010   ISBN: 978-1-904455-58-5
Price: GB £159 or US $310
A comprehensive guide to Borrelia providing an encyclopedic overview of the molecular biology of this important genus and the pathogenesis of diseases Borellia causes. Leading authorities have contributed chapters on topics such as Borrelia genomics, DNA replication, gene regulation, transcriptomics, proteomics, metabolism and physiology, cellular structure, motility and chemotaxis, genetic manipulation, evolutionary genetics, ecology, tick interactions, Lyme disease and relapsing fever pathogenesis, animal models, host response, detection, and vaccines read more ...
Influenza: Molecular VirologyEdited by: Qinghua Wang and Yizhi Jane Tao
Published: 2010   ISBN: 978-1-904455-57-8
Price: GB £159 or US $310
H1N1 influenza subtype causes a relatively mild infection in humans, however it is highly transmittable between people and a new influenza pandemic has been declared. If this virus were to acquire some of the lethal capabilities of H5N1, then the ensuing pandemic could be devastating. This book critically reviews the current research and the most important discoveries in this highly topical field. Subjects covered include the NS1 protein of influenza A virus, the structure of influenza NS1, influenza B hemagglutinin, influenza A nucleoprotein, influenza A hemagglutinin glycoproteins, the M2 channel, virulence genes of the 1918 pandemic influenza, influenza virus polymerase, gene diagnostic microarrays, and computer-assisted vaccine design. read more ...
RNA Interference and Viruses: Current Innovations and Future TrendsEdited by: Miguel Angel Martínez
Published: 2010   ISBN: 978-1-904455-56-1
Price: GB £159 or US $310
In this book, expert RNAi specialists from around the world have teamed up to produce a timely and thought-provoking review of the area. The two central themes are the latest findings on RNAi-virus interactions and the current progress in the development of RNAi-based antiviral therapeutics. A number of chapters explain general concepts concerned with the role of RNAi in natural antiviral defense mechanisms, other chapters discuss how to improve the efficacy and safety of RNAi-based antiviral drugs, while others describe how this technology is being developed as a new therapeutic tool for fighting specific viruses, including HIV, HCV and respiratory viruses. Authors also outline potential new avenues for research thus providing a stimulus for further research. read more ...
Retroviruses: Molecular Biology, Genomics and PathogenesisEdited by: Reinhard Kurth and Norbert Bannert
Published: 2010   ISBN: 978-1-904455-55-4
Price: GB £159 or US $310
Written by the top retroviral specialists, this book reviews the genomics, molecular biology, and pathogenesis of these important viruses, comprehensively covering all the recent advances. Topics include: host and retroelement interactions, endogenous retroviruses, retroviral proteins and genomes, viral entry and uncoating, reverse transcription and integration, transcription, splicing and RNA transport, pathogenesis of oncoviral infections, pathogenesis of immunodeficiency virus infections, retroviral restriction factors molecular vaccines and correlates of protection, gammaretroviral and lentiviral vectors, non-primate mammalian and fish retroviruses, simian exogenous retroviruses, and HTLV and HIV. read more ...
Metagenomics: Theory, Methods and ApplicationsEdited by: Diana Marco
Published: 2010   ISBN: 978-1-904455-54-7
Price: GB £159 or US $310
The diverse and multiple aspects of metagenomics and the multiplicity of its potential applications. The new theoretical insights, the more recent applications, and the dynamically developing methods of data acquisition and analysis. Essential reading for all researchers wishing to broaden their knowledge of metagenomics and highly recommended for those new to the field. read more ...
Aspergillus: Molecular Biology and GenomicsEdited by: Masayuki Machida and Katsuya Gomi
Published: 2010   ISBN: 978-1-904455-53-0
Price: GB £159 or US $310
In this book leading Aspergillus researchers review and summarise the most important aspects of Aspergillus molecular biology and genomics. The book opens with a fascinating overview of the genus Aspergillus. This is followed by in-depth reviews of the Aspergillus molecular systematics, comparative genomics, bioinformatics and systems biology of Aspergillus, transcriptional regulation, genetics and genomics of sexual development of A. nidulans, genomics and secondary metabolism, ecology, development and gene regulation in A. flavus, functional systems biology, and novel industrial applications of A. oryzae genomics. Essential reading for everyone with an interest in Aspergillus and related fungi. read more ...
Environmental Molecular MicrobiologyEdited by: Wen-Tso Liu and Janet K. Jansson
Published: 2010   ISBN: 978-1-904455-52-3
Price: GB £159 or US $310
The current state-of-the-art of environmental microbiology with an emphasis on molecular biology and genomics. A range of technologies and their applications in environmental microbiology. The book focuses on the microbial diversity and phylogeny of microorganisms in the environment and describes the molecular toolbox currently available for the study of the composition and diversity of microbial communities and their functions. Also covers the application of these approaches in various environments including soil, marine water, plants, humans and wastewater treatment. read more ...
Neisseria: Molecular Mechanisms of PathogenesisEdited by: Caroline Genco and Lee Wetzler
Published: 2010   ISBN: 978-1-904455-51-6
Price: GB £150 or US $310
The latest theory and clinical significance of molecular mechanisms in meningococcal disease. Leading authorities have contributed chapters on topics such as gene expression, genomics, biofilms, denitrification, adhesion strategies, mechanisms of cellular invasion, inate immunity, complement, apoptosis, acquired immunity, vaccine development, epidemiology and antibiotic resistance. read more ...
ABC Transporters in Microorganisms: Research, Innovation and Value as Targets against Drug ResistanceEdited by: Alicia Ponte-Sucre
Published: 2009   ISBN: 978-1-904455-49-3
Price: GB £150 or US $310
The topics include the structure, physiology and evolution of ABC transporters, and their special characteristics in bacteria, yeast, trypanosomes and malaria parasites. The book covers the most recent research into the role of ABC transporters in the design of strategies to circumvent drug resistance. Each chapter comprises an exhaustive review of the particular topic from both the scientific and clinical perspective. read more ...
Pili and Flagella: Current Research and Future TrendsEdited by: Ken Jarrell
Published: 2009   ISBN: 978-1-904455-48-6
Price: GB £150 or US $310
The current knowledge and latest research on prokaryotic pili and flagella. The emphasis is on the molecular biology, genetics, structure, assembly and function of these structures. read more ...
Lab-on-a-Chip Technology: Biomolecular Separation and AnalysisEdited by: Keith E. Herold and Avraham Rasooly
Published: 2009   ISBN: 978-1-904455-47-9
Price: GB £150 or US $310
Applications of lab-on-a-chip devices in biotechnology, medicine, clinical diagnostics, chemical engineering, and pharmaceutics. Various electrophoresis and liquid chromatography applications, methods for cell separation, blood cell separation, clinical applications, protein, genetic, PCR, transcriptome analysis, cell manipulation and analysis, cell viability analysis, microorganism capturing. read more ...
Lab-on-a-Chip Technology: Fabrication and MicrofluidicsEdited by: Keith E. Herold and Avraham Rasooly
Published: 2009   ISBN: 978-1-904455-46-2
Price: GB £150 or US $310
Current lab-on-a-chip technologies including theoretical and technical information for the understanding of the technology and the reproduction of experiments. Will help the understanding of current LOC technologies, performance of similar experiments, the design of new LOC systems and development of new methodologies and applications. read more ...
Bacterial Polysaccharides: Current Innovations and Future TrendsEdited by: Matthias Ullrich
Published: 2009   ISBN: 978-1-904455-45-5
Price: GB £150 or US $310
In this timely book a cohort of experienced and authoritative experts review the most important innovations in research on and biotechnological applications of bacterial polysaccharides. The book takes an interdisciplinary view that examines this fascinating subject area in detail from molecular biology, genome-, transcriptome- and proteome-wide perspectives, and looks at the ecological aspects and systems biology approaches. Hence the book provides a sound basis for future research directions including high efficiency applications of bacterial polysaccharides in medicine, the food industry, and renewable energy production. read more ...
Microbial Toxins: Current Research and Future TrendsEdited by: Thomas Proft
Published: 2009   ISBN: 978-1-904455-44-8
Price: GB £150 or US $310
This timely volume serves as an update on the most important microbial toxins. Written by internationally respected scientists, topics reviewed include: toxins carried by mobile genetic elements, botulinum neurotoxins, anthrax, subtilase cytotoxin, Pasteurella multocida toxin, RTX toxins of vibrios, vacA toxin, staphylococcal immune evasion toxins and fungal ribotoxins. read more ...
Acanthamoeba: Biology and PathogenesisAuthor: Naveed Khan
Published: 2009   ISBN: 978-1-904455-43-1
Price: GB £150 or US $310
Everything that is known about Acanthamoeba is critically reviewed and divided into easy-to-follow sections. The current state of research on genomics, molecular and cellular biology, life cycles, geographical distribution, role in ecosystem, morphology, motility, phylogenetics, genotyping, metabolism, regulation of morphogenesis, host-parasite interactions, the molecular and immunological basis of pathogenesis, methods of transmission, epidemiology, clinical manifestation, diagnosis, treatment, new target development and drug resistance, and much more. read more ...
Bacterial Secreted Proteins: Secretory Mechanisms and Role in PathogenesisEdited by: Karl Wooldridge
Published: 2009   ISBN: 978-1-904455-42-4
Price: GB £150 or US $310
A broad and in-depth description of the current knowledge of bacterial protein secretion and its role in pathogenesis. This publication on bacterial secreted proteins, the secretory systems of bacteria and the vital role of secreted proteins in bacterial pathogenesis is aimed at microbiologists, molecular biologists, public health scientists and researchers engaged in the study of pathogenesis, drug design and vaccine development. read more ...
Lactobacillus Molecular Biology: From Genomics to ProbioticsEdited by: Åsa Ljungh and Torkel Wadström
Published: 2009   ISBN: 978-1-904455-41-7
Price: GB £150 or US $310
A major new reference for all medical researchers, dairy technologists, microbiologists and biotechnologists in the academic and industrial sectors. Written by an international team of scientists the volume focuses on recent research on the molecular biology and genomics of Lactobacillus. Topics covered include phylogenetics, taxonomy, comparative genomics, functional genomics, the intestinal microflora, surface proteins, stress responses, interaction with the immune system, probiotics, anti-cancer potential, and much more. Essential reading for all scientists involved with lactic acid bacteria or probiotic research and a recommended book for all microbiology laboratories. read more ...
Mycobacterium: Genomics and Molecular BiologyEdited by: Tanya Parish and Amanda Brown
Published: 2009   ISBN: 978-1-904455-40-0
Price: GB £150 or US $310
A critical review of the current and most recent advances in the genomics and molecular biology of mycobacteria. Focuses on the topical and most relevant aspects. Includes strain variation and evolution, hypervirulent strains, electron transport and respiration, lipid biosynthesis, DNA repair, oxygen signaling, sulphur metabolism, protein secretion, the protein kinase family. read more ...
Clostridia: Molecular Biology in the Post-genomic EraEdited by: Holger Brüggemann and Gerhard Gottschalk
Published: 2009   ISBN: 978-1-904455-38-7
Price: GB £150 or US $310
In this book internationally recognised Clostridium experts critically review the most important aspects of clostridial research, providing the first coherent picture of the organism's molecular and cellular biology in this post-genomic era. The first major focus of the book is the genetics and molecular biology of the major clostridial toxins including: botulinum and tetanus neurotoxins, C. difficile large exotoxins, C. perfringens enterotoxin, pore-forming and binary bacterial toxins. Other topics include: molecular epidemiology of C. botulinum and C. difficile, metabolic networks in C. acetobutylicum, development of genetic knock-out systems for clostridia, surface structures, anti tumor potential of clostridia, and antibiotic resistance determinants in C. difficile. read more ...
Plant Pathogenic Bacteria: Genomics and Molecular BiologyEdited by: Robert W. Jackson
Published: 2009   ISBN: 978-1-904455-37-0
Price: GB £150 or US $310
In this book, internationally acclaimed experts review the most important developments providing an invaluable, up-to-date summary of the molecular biology and genomics of plant pathogenic bacteria. The book opens with two chapters on bacterial evolution, diversity and taxonomy, topics that have been transformed by molecular biology and genomics analyses. The third chapter delves into the crucially understudied area of pathogen adaptation to the plant apoplast environment. The following seven chapters focus on specific plant pathogens: Agrobacterium, Leifsonia, Pectobacterium, Pseudomonas, Ralstonia, Xanthomonas, and Xylella. The next four chapters review specific, intensively studied areas of research in the plant pathogen field: microbe associated molecular patterns (MAMPs) and innate immunity; use of bacterial virulence factors to suppress plant defence; cyclic di-GMP signalling and the regulation of virulence; and plasmids and the spread of virulence. The final chapter covers the critical area of bioinformatics. read more ...
Microbial Production of Biopolymers and Polymer Precursors: Applications and PerspectivesEdited by: Bernd H. A. Rehm
Published: 2009   ISBN: 978-1-904455-36-3
Price: GB £150 or US $310
Describes in detail the use of microorganisms for the production of the most important biopolymers and polymer precursors. The authors describe, in depth, the biosynthetic pathways, physical properties and industrial production processes and discuss in detail the genetic and metabolic engineering of microorganisms for biopolymer production. Also highlighted are the applications and potential applications of the biopolymers and microbial biotechnology read more ...
Plasmids: Current Research and Future TrendsEdited by: Georg Lipps
Published: 2008   ISBN: 978-1-904455-35-6
Price: GB £150 or US $310
Written by acknowledged experts in the field, this volume provides an up to date treatment of the structure, function and application of plasmids with a particular emphasis on current and future trends. The book is aimed primarily at research scientists, graduate students and professional scientists but will also be of great interest to all molecular biologists and microbiologists involved in research or teaching. Chapters include a historical perspective on E. coli plasmids and the scientific background of the plasmids used routinely in laboratories to clone genes and to express proteins; an overview on the plasmids of archaea and eukarya; bioinformatic tools; horizontal gene transfer and the process of DNA transfer. Two entire chapters are devoted to the important medical applications of plasmids, including the correction of gene defects and vaccines to treat cancer or infectious diseases. read more ...
Pasteurellaceae: Biology, Genomics and Molecular AspectsEdited by: Peter Kuhnert and Henrik Christensen
Published: 2008   ISBN: 978-1-904455-34-9
Price: GB £150 or US $310
Pasteurella book. In this timely book, leading international Pasteurellaceae scientists critically review the most important current research providing an up-to-date review of the molecular biology, genomics and virulence of these fascinating organisms. Topics covered include taxonomy and biodiversity, phylogeny, comparative genomics, competence, DNA uptake and transformation, proteomics and protein secretion, RTX toxins, lipopolysaccharides, biofilms, quorum sensing, antimicrobial resistance, diagnosis, and OMP and iron uptake. Each chapter is independent and can be read in isolation and as a whole the book provides an important resource summarising our current knowledge of Pasteurellaceae genomics and molecular biology. Essential reading for everyone working on Pasteurellaceae and related organisms. read more ...
Vibrio cholerae: Genomics and Molecular BiologyEdited by: Shah M. Faruque and G. Balakrish Nair
Published: 2008   ISBN: 978-1-904455-33-2
Price: GB £150 or US $310
In this book leading V. cholerae experts, the chapters review the most important cutting-edge genetic facets of V. cholerae including its genomic organization, population genetics, molecular epidemiology, and synchronized regulation of gene expression. Other topics include the molecular basis for enhanced transmissibility of cholera during epidemics, survival of the pathogen in the environment, and above all the evolution of the species to attain increased fitness both as a pathogen and an environmental organism. Essential reading for everyone with an interest in Vibrio and recommended reading for other scientists working in microbial pathogenesis, microbial genomics and antimicrobial research. read more ...
Pathogenic Fungi: Insights in Molecular BiologyEdited by: Gioconda San-Blas and Richard A. Calderone
Published: 2008   ISBN: 978-1-904455-32-5
Price: GB £150 or US $310
In this book a panel of expert international mycologists critically review the most important cutting-edge topics. Chapters are written from a molecular and genomic perspective and through the provision of extensive reference sections positively encourage readers to pursue the subject in greater detail. Topics include: gene expression and regulation, heterozygosity in Candida, molecular diagnosis, regulation of the host-fungal interaction, the development of anti-fungals, signal transduction, and mechanisms of multi-drug resistance. read more ...
Helicobacter pylori: Molecular Genetics and Cellular BiologyEdited by: Yoshio Yamaoka
Published: 2008   ISBN: 978-1-904455-31-8
Price: GB £150 or US $310
Helicobacter is leading cause of peptic ulcers, gastritis and gastric cancer worldwide, therefore has been the subject of intensive research. As the number of publications in this field has risen dramatically in recent years, it is extremely difficult for even the most diligent reader to stay abreast of progress. This book distills the most important cutting-edge findings in the field to produce a timely and comprehensive review. With contributions from leading international helicobacter researchers, topics include: lipopolysaccharides, outer membrane proteins, motility and chemotaxis, type IV secretions systems, metal metabolism, molecular mechanisms of host adaptation, genomotyping, and proteonomics. read more ...
Corynebacteria: Genomics and Molecular BiologyEdited by: Andreas Burkovski
Published: 2008   ISBN: 978-1-904455-30-1
Price: GB £150 or US $310
Leading Corynebacteria experts provide a description of the current state-of-the-art molecular biology toolbox available for Corynebacterium research, including global analyses techniques such as comparative genomics, transcriptome, proteome and metabolome analysis as well as the most recent knowledge on Corynebacterium promoter structures and vector systems. Furthermore, topics such as regulatory networks controlling carbon, nitrogen, phosphorus, sulphur and iron metabolism, cell wall structure, proteolysis and environmental stress response are covered. Essential reading for all Corynebacterium scientists and everyone with an interest in global analysis techniques, global regulation and systems biology. read more ...
Staphylococcus: Molecular GeneticsEdited by: Jodi Lindsay
Published: 2008   ISBN: 978-1-904455-29-5
Price: GB £150 or US $300
This volume, the first to focus on the stapyhlococcal genetics provides a state-of-the art overview of the field. Topics include the sequencing projects, including spin-off microarray and systems biology tools, epidemiology, evolution, manipulation of the genome, diagnostics, gene expression due to global regulators and environmental triggers, cell-wall synthesis, coagulase-negative species, and animal pathogens. It is designed for two major audiences. Firstly, to introduce the subject to new researchers, including those unfamiliar with genetics. Secondly, for established researchers, for whom it will serve as an invaluable reference and summary of a large field, as well as presenting the latest advances and future trends written by those who are developing them. read more ...
Leishmania: After The GenomeEdited by: Peter J. Myler and Nicolas Fasel
Published: 2008   ISBN: 978-1-904455-28-8
Price: GB £150 or US $300
In this book, internationally recognised Leishmania experts critically review the most important aspects of current Leishmania research, providing the first coherent picture of the organism's molecular and cellular biology since the publication of the genome sequence. Chapters are written from a molecular and genomic perspective and discuss in depth Leishmania-specific aspects of trypanosomatid biology and pathology. Topics include: diagnosis and epidemiology, genome structure and content, regulation of gene expression, the Leishmania proteome, the Leishmania metabolome, Leishmania differentiation, interaction with the sand fly vector, drug discovery, drug resistance, and much more. Essential reading for all researchers working with Leishmania, trypanosomes and protozoa. A recommended book for all biology and medical libraries. read more ...
Archaea: New Models for Prokaryotic BiologyEdited by: Paul Blum
Published: 2008   ISBN: 978-1-904455-27-1
Price: GB £150 or US $300
In our Archaea: New Models for Prokaryotic Biology book, the authors present an expanding pattern of new information relevant to both the general and the technical reader. The book focuses on molecular biology and genomics and topics include the biology of metals, redox chemistry, respiration, sugar catabolism, nucleic acid modification, DNA replication, repair and recombination, transcriptomics, signal transduction and peptide antibiotics. Throughout the well referenced text the emphasis is on emerging topics in specific fields providing the reader with a vision of the future in the expanding world of Archaea. read more ...
Legionella: Molecular MicrobiologyEdited by: Klaus Heuner and Michele Swanson
Published: 2008   ISBN: 978-1-904455-26-4
Price: GB £150 or US $300
The current state of many of the most critical features of Legionella. Authors have contributed papers describing and discussing the latest research findings with an emphasis on molecular aspects. Recommended for all microbiology and clinical research laboratories. read more ...
Molecular Oral MicrobiologyEdited by: Anthony H. Rogers
Published: 2008   ISBN: 978-1-904455-24-0
Price: GB £150 or US $300
The molecular biology of micro-organisms involved in the two major dental diseases: caries and periodontal disease. Research has focused on factors which might modulate the interaction between the resident oral bacteria and the host. read more ...
Animal Viruses: Molecular BiologyEdited by: Thomas C. Mettenleiter and Francisco Sobrino
Published: 2008   ISBN: 978-1-904455-22-6
Price: GB £150 or US $300
An international panel of leading virologists provide a state-of-the-art overview of the field, comprehensively detailing the current understanding of viruses, their replication, evolution and interaction with the host. read more ...
Segmented Double-stranded RNA Viruses: Structure and Molecular BiologyEdited by: John T. Patton
Published: 2008   ISBN: 978-1-904455-21-9
Price: GB £150 or US $300
This timely book brings together all of the key recent research on this disparate group of viruses, providing for the first time a single resource reviewing dsRNA viral structure and molecular biology. Written by well respected and experienced virologists, topics include: the structures of orthoreoviruses, rotavirus, phytoreoviruses, and bluetongue virus, entry into the bacterial cell, crystal structure of reovirus polymerase λ3, assembly of the reovirus genome, genomic RNA packaging and replication in the Cystoviridae, and much more. Essential reading for all dsRNA virologists and all other virologists with an interest in molecular and structural biology. read more ...
Acinetobacter Molecular BiologyEdited by: Ulrike Gerischer
Published: 2008   ISBN: 978-1-904455-20-2
Price: GB £150 or US $300
Expert international authors have contributed chapters on diverse topics including taxonomy, lipopolysaccharides, catabolism of aromatic compounds, transformation systems, transcriptional regulation, applications in biotechnology, the molecular basis for virulence and pathogenicity, molecular epidemiology, and antibiotic resistance. This book is highly recommended for anyone involved in Acinetobacter research. read more ...
Pseudomonas: Genomics and Molecular BiologyEdited by: Pierre Cornelis
Published: 2008   ISBN: 978-1-904455-19-6
Price: GB £150 or US $300
This concise volume reviews the most current and topical aspects of Pseudomonas molecular biology and genomics and is aimed at a readership of research scientists, graduate students and other specialists. Renowned international authors have contributed chapters on diverse topics including taxonomy, genome diversity, oligonucleotide usage, polysaccharides, pathogenesis, virulence, biofilms, antibiotic resistance and iron uptake. In addition an entire chapter is devoted to the genetic tools being developed to take full advantage of the wealth of information generated by the genome sequencing efforts. read more ...
Real-Time PCR in Microbiology: From Diagnosis to CharacterizationEdited by: Ian M. Mackay
Published: 2007   ISBN: 978-1-904455-18-9
Price: GB £150 or US $300
This invaluable book describes and explains some of the more complex aspects of real-time PCR presenting a background for the novice, a theoretical reference for the experienced user, and useful discussions of future developments. Chapters address the basics of PCR history, oligonucleotide design, target preparation, standardisation, quantification, various applications, and future challenges. The final chapter is presented in the format of a roundtable discussion providing an insightful, topical and interesting discourse with contributions from over 30 authorities and experts on real-time PCR. read more ...
Microbial Biodegradation: Genomics and Molecular BiologyEdited by: Eduardo Díaz
Published: 2008   ISBN: 978-1-904455-17-2
Price: GB £150 or US $300
Expert international authors critically review all of the most important topics in this exciting field. Although other books covering this are currently available, this book is unique in that it is the first to review the area from a molecular biology and genomics perspective. Topics covered include: aerobic and anaerobic biodegradation of aromatic compounds, molecular detection methods e.g. microautoradiography, mRNA analyses, etc., genome-based predictive modelling, elucidation of regulatory networks, bioavailability, chemotaxis and transport issues, functional genomic analyses, natural attenuation, community fingerprinting and metagenomics, biotreatment, and biocatalysts engineering. Essential reading for microbial degradation and bioremediation scientists and of general interest for microbiologists working in field of environmental microbiology. read more ...
Coronaviruses: Molecular and Cellular BiologyEdited by: Volker Thiel
Published: 2007   ISBN: 978-1-904455-16-5
Price: GB £75 or US $149
In this timely book, internationally renowned experts review literally every aspect of cutting edge coronavirus research providing the first coherent picture of the molecular and cellular biology since the outbreak of SARS in 2003. The book is divided into two sections: Part I focuses on the molecular biology of the virus itself and includes topics such as coronavirus binding and entry, replicase gene function, cis-acting RNA elements, coronavirus discontinuous transcription, reverse genetics, genome packaging and molecular evolution. In Part II of the book, the focus is on molecular and cellular pathogenesis and infection control. read more ...
The Cyanobacteria: Molecular Biology, Genomics and EvolutionEdited by: Antonia Herrero and Enrique Flores
Published: 2008   ISBN: 978-1-904455-15-8
Price: GB £150 or US $300
This volume brings together the expertise and enthusiasm of an international panel of leading cyanobacterial researchers to provide a state-of-the art overview of the field. Topics covered include: evolution, comparative genomics, gene transfer, molecular ecology and environmental genomics, stress responses, bioactive compounds, circadian clock, structure of the photosynthetic apparatus, membrane systems, carbon acquisition, nitrogen assimilation and C/N balance sensing and much more. Essential for anyone with an interest in cyanobacteria, bacterial photosynthesis, bacterial nitrogen fixation, and symbosis. read more ...
Bacteriophage: Genetics and Molecular BiologyEdited by: Stephen Mc Grath and Douwe van Sinderen
Published: 2007   ISBN: 978-1-904455-14-1
Price: GB £150 or US $300
Written by eminent international researchers actively involved in the disparate areas of bacteriophage research this book focuses on the current rapid developments in this exciting field. The book opens with an excellent chapter that provides a broad overview of the topics and also highlights the multifaceted nature of bacteriophage research. This is followed by a series of reviews that focus on the current most cutting-edge topics including bioinformatics and genomics, phage in the environment, bacteriophage in medicine, transfer of phage DNA to the host, contribution to host phenotype and much more. read more ...
Candida: Comparative and Functional GenomicsEdited by: Christophe d'Enfert and Bernhard Hube
Published: 2007   ISBN: 978-1-904455-13-4
Price: GB £150 or US $300
International experts provide comprehensive and authoritative reviews of current research on Candida. Essential reading for all Candida genome and molecular biology researchers and a recommended text for scientists working on fungal genomics and molecular biology. read more ...
Bacillus: Cellular and Molecular BiologyEdited by: Peter Graumann
Published: 2007   ISBN: 978-1-904455-12-7
Price: GB £150 or US $300
An overview of the most recent and most exciting research providing a picture of the major cytological aspects of this model bacterium. Includes replication and segregation of the chromosome, cell division, replication and growth, the cell cycle, transcription, translation, regulation, the actin cyctoskeleton, the cell membrane and cell wall, biofilm formation and sporulation, DNA repair, the regulation of transcription through RNA molecules, and the regulation of protein activity through proteolysis. read more ...
Pathogenic Treponema: Molecular and Cellular BiologyEdited by: Justin D. Radolf and Sheila A. Lukehart
Published: 2006   ISBN: 978-1-904455-10-3
Price: GB £69 or US $139
The focus of the book is on recent advances and new developments in Treponema research, in particular those resulting from modern molecular and genetic methodologies. Topics covered include the phylogenic diversity, comparative genomics, metabolism and cultivation, motility, antigenic variation, immunology of syphilis, the use cultivatable treponemes as surrogates for T. pallidum, oral treponemes, and much much more. read more ...
Alpha Herpesviruses: Molecular and Cellular BiologyEdited by: R. M. Sandri-Goldin
Published: 2006   ISBN: 978-1-904455-09-7
Price: GB £140 or US $280
The alpha herpesviruses are an important group of viruses. In this timely book internationally recognized experts, highlight the more provocative and exciting findings in herpesvirus research. Each chapter is a review of a specific area with an emphasis on recent advances and the latest developments. Topics include: multifunctional proteins, advances in DNA replication, new information on the regulation of gene expression, the emergence of new technologies, recent technological advances in fluorescent probes, the induction of apoptosis, the disruption of interferon, vaccine development and drug design. read more ...
PCR Troubleshooting: The Essential GuideAuthor: Michael L. Altshuler
Published: 2006   ISBN: 978-1-904455-07-3
Price: GB £30 or US $60
A unique PCR troubleshooting guide that is an essential companion for anyone who uses the polymerase chain reaction technique. read more ...
Papillomavirus Research: From Natural History To Vaccines and BeyondEdited by: M. Saveria Campo
Published: 2006   ISBN: 978-1-904455-04-2
Price: GB £150 or US $300
In this timely book leading scientists review current aspect of papillomavirus research providing a fascinating insight into papillomavirus molecular biology, interactions with the host, immunology and vaccine development. Topics covered include epidemiology and taxonomy, phylogenetic analyses, gene expression, regulation of DNA replication, transcription factor proteins, organotypic raft cultures, virus-like particles, and much more. Essential reading for scientists and researchers working on papillomavirus and a recommended text for anyone involved with antiviral drug and vaccine development. read more ...
Epstein-Barr VirusEdited by: Caister Academic Press Editor: Erle S. Robertson
Published: 2005   ISBN: 978-1-904455-03-5
Price: GB £150 or US $300
World renowned EBV experts provide a critical and comprehensive review of every aspect of this important virus. By integrating genetic, immunologic, and cell biologic approaches to elucidate pathogenesis, penetrating new insights into the molecular and cellular interaction between EBV and its human host have emerged. Topics covered include: Discovery, history and seroepidemiology, EBV and the immune response, EBV genetics, EBV infection and persistence, latency, lytic proteins and reactivation control, vaccine approaches, animal models, and the future of EBV studies. This is essential reading for all EBV virologists as well as clinical and research scientists working on oncogenic viruses. read more ...
Cytomegaloviruses: Molecular Biology and ImmunologyEdited by: Matthias J. Reddehase
Published: 2006   ISBN: 978-1-904455-02-8
Price: GB £140 or US $280
Leading international experts provide comprehensive and authoritative reviews on every aspect of current research. By integrating viral genomics, proteomics, immunology and molecular biology with the emerging knowledge of the genomics of the host organism, penetrating new insights into the virus-host interaction are provided. The focus of the book is on the molecular and genomic aspects and the authors provide an insight into the current understanding of the subject and the future direction of research. Topics covered include disease mechanisms, genomics, proteomics, BAC mutagenesis, virus entry and activation of innate immunity, regulation of viral gene expression, regulation of viral mRNA export, animal models of infection, novel therapeutics, vaccine development, antivirals, and much more. read more ...
Probiotics and Prebiotics: Scientific AspectsEdited by: Gerald W. Tannock
Published: 2005   ISBN: 978-1-904455-01-1
Price: GB £99 or US $199
Food scientists and nutritionists have accepted, relatively uncritically, the concepts underlying the use of probiotics and prebiotics in the promotion of health. Microbiologists and medical practitioners have viewed these products more sceptically. Much more scientific and medical validation of probiotic or prebiotic use is required. This will entail the use of sophisticated analytical methodologies. Knowledge of the gut microbiota has increased dramatically during the past decade thanks largely to the results obtained from the application of nucleic acid-based methodologies. Because of the availability of improved technologies, detailed studies of the two principal kinds of probiotic or prebiotic bacteria, Lactobacillus and Bifidobacterium, can be made. Emerging leaders have contributed chapters to this book that therefore represents a state of the art compendium of fundamental science related to early 21st century probiotic or prebiotic research. read more ...
Foodborne Pathogens: Microbiology and Molecular BiologyEdited by: Pina M. Fratamico, Arun K. Bhunia, and James L. Smith
Published: 2005   ISBN: 978-1-904455-00-4
Price: GB £149 or US $299
Written by leaders in the field, this book represents a cutting edge summary of all the latest advances, providing the first coherent picture of the current status. Opening chapters tackle topics such as pathogen detection (molecular, biosensor), molecular typing, viable but non-culturable organisms, predictive modeling, and stress responses. The next section covers groups of organisms: enteric viruses, protozoan parasites, and mycotoxins. This is followed by chapters on specific bacteria: Yersinia enterocolitica, Vibrio spp., Staphylococcus aureus, Campylobacter Infections, Listeria monocytogenes, Salmonella spp., Shigella spp., Escherichia coli, Clostridium botulinum, Clostridium perfringens and Bacillus cereus. The final chapters provide a fascinating review of the ability of pathogens to contaminate a food supply and provide an overview of emerging foodborne pathogens. read more ...
Foodborne Pathogens: Microbiology and Molecular Biology | Paperback BookEdited by: Pina M. Fratamico, Arun K. Bhunia, and James L. Smith
Published: 2008   ISBN: 978-1-898486-52-7
Price: GB £99 or US $199
Written by leaders in the field, this book represents a cutting edge summary of all the latest advances, providing the first coherent picture of the current status. Opening chapters tackle topics such as pathogen detection (molecular, biosensor), molecular typing, viable but non-culturable organisms, predictive modeling, and stress responses. The next section covers groups of organisms: enteric viruses, protozoan parasites, and mycotoxins. This is followed by chapters on specific bacteria: Yersinia enterocolitica, Vibrio spp., Staphylococcus aureus, Campylobacter Infections, Listeria monocytogenes, Salmonella spp., Shigella spp., Escherichia coli, Clostridium botulinum, Clostridium perfringens and Bacillus cereus. The final chapters provide a fascinating review of the ability of pathogens to contaminate a food supply and provide an overview of emerging foodborne pathogens. read more ...
HIV Chemotherapy: A Critical ReviewEdited by: Salvatore T. Butera
Published: 2005   ISBN: 978-0-9542464-9-5
Price: GB £110 or US $220
Expert AIDS researchers critically review every aspect of this highly topical subject. Chapters deal with the management of HIV infections, strategies to protect and strengthen the host immune system at the cellular level, strategies required for the implementation of effective anti-HIV therapies in developing countries, the genetics of viral drug resistance, current drug-resistance testing technologies, the latest viral and cellular targets for anti-HIV chemotherapy, the development of iRNA based therapeutics and molecular based strategies that target latent virus reservoirs in infected individuals. Essential reading for scientists and clinicians working on AIDS, HIV, and other retroviruses as well as all health care professionals interested in expanding their current understanding of the subject. read more ...
Pathogenic Fungi: Host Interactions and Emerging Strategies for ControlEdited by: Gioconda San-Blas and Richard A. Calderone
Published: 2004   ISBN: 978-0-9542464-8-8
Price: GB £99 or US $199
This book, together with its companion volume "Pathogenic Fungi: Structural Biology and Taxonomy", brings together expert international authors who critically review current topics, and through the provision of extensive reference sections positively encourage readers to pursue the subject in greater detail. The book is divided into two sections: "Fungal Interactions with the Host" and "Antifungal Antibiotics". The emphasis of the first section is focused on the two-way recognition systems that exist between the host and the fungus. Experts in fungal-host interactions discuss new initiatives for alternatives to drug therapy through the development of vaccines and passive antibody therapy. In the "Antifungal Antibiotics" section, new target development, molecular modelling, and drug resistance, both at the individual organism level, and in a biofilm, are featured. read more ...
Pathogenic Fungi: Structural Biology and Taxonomy | BookEdited by: Gioconda San-Blas and Richard A. Calderone
Published: 2004   ISBN: 978-0-9542464-7-1
Price: GB £99 or US $199
Expert international authors critically review current topics and positively encourage readers to pursue the subject in greater detail.The book is divided into two sections: "Fungal Dimorphism and Pathogenicity" and "New Taxonomic Tools". The first section focuses on morphogenesis, the cell cycle, and the cell wall of human pathogens. These play a major role in elucidating fungal relationships, both with the environment and with the host. Experts in fungal structural biology contribute in-depth reviews on a variety of topics with a focus on molecular and biochemical analysis. The final chapter presents a review of how mathematical modelling is used to understand the building of three-dimensional cell structures in the morphogenetic process. The second section presents novel approaches to aid the understanding of strain variability, the significance of environmental and patient strains, and the relatedness of "uncultured" fungi. In addition the use of molecular tools forthe taxonomic classification of previously unclassifiable fungi is featured. read more ...
Malaria Parasites: Genomes and Molecular BiologyEdited by: A.P. Waters and C.J. Janse
Published: 2004   ISBN: 978-0-9542464-6-4
Price: GB £115 or US $230
The completion of the Plasmodium falciparum genome sequence in late 2002 hearlded a new era in malaria research. The search could begin in earnest for new drugs and vaccines to combat malaria, a disease which afflicts up to 500 million people worldwide and is responsible for the deaths of more than one million people each year. More importantly, it should enable a greater understanding of the living parasite and it's interaction with the insect vector and human host. In this book internationally renown experts provide up to date reviews of the most important aspects of post-genomic malaria research. Topics covered include: the P. falciparum genome and model parasites, bioinformatics and genome databases, microsatellite analysis, analysis of chromosome structure, cell cycle to RNA polymerase I and II mediated gene expression, role of the nuclear genome, the parasite surface and cell biology, and much much more. read more ...
MRSA: Current PerspectivesEdited by: Ad C. Fluit and Franz-Josef Schmitz
Published: 2003   ISBN: 978-0-9542464-5-7
Price: GB £90 or US $180
Methicillin-resistant S. aureus (MRSA) strains continue to present unique challenges to clinicians, microbiologists, and the molecular biologists around the world. These organisms are typically resistant to several other antimicrobial agents, including aminoglycosides, chloramphenicol, clindamycin, fluoroquinolones and macrolides and are susceptible only to vancomycin. Internationally renown authors comprehensively review all aspects of MRSA research. Topics covered include strategies for the detection and typing of MRSA strains, epidemiological characterisation, molecular evolution of MRSA, vancomycin resistant S. aureus, mechanisms of methicillin resistance, virulence mechanisms in MRSA pathogenesis, recommended treatment of MRSA infections and options for the prevention and control of MRSA infections. read more ...
Genomics of GC-Rich Gram-Positive BacteriaEdited by: Antoine Danchin
Published: 2002   ISBN: 978-0-9542464-3-3
Price: GB £75 or US $150
Eminent scientists have contributed comprehensive reviews on all aspects of the genomics of Rhodococcus, Mycobacteria, Streptomyces and other organisms. The authors provide an insight into the many facets of large-scale functional investigation in a variety of bacteria with the explicit goal to find common rules in the dynamic and structural organisation of these organisms. This volume is the definitive guide to current research in this increasingly important area. read more ...
Probiotics and Prebiotics: Where are We Going?Edited by: Gerald W. Tannock
Published: 2002   ISBN: 978-0-9542464-1-9
Price: GB £90 or US $180
Contains state-of-the-art commentaries on all aspects of the intestinal microflora and probiotics and provides an authoritative review of important aspects of probiotic and prebiotic research. Written by leading experts in the field, each chapter affords a critical insight to a particular topic, reviews current research, discusses future direction and aims to stimulate discussion. Topics covered include the genomics of probiotic microorganisms, the developing technologies for analysis of gut microorganisms, evaluation and future potential of prebiotic substances, and the potential for disease prevention in the host by probiotic organisms. read more ...